Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Flora Doffe"'
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 6, Pp 853-865 (2022)
Aim: Functional screening of new pharmaceutical compounds requires clinically relevant models to monitor essential cellular and immune responses during cancer progression, with or without treatment. Beyond survival, the emergence of resistant tumor c
Externí odkaz:
https://doaj.org/article/5b0ee704d43c4b349ddd2ffa9c075f11
Autor:
Hellen Daghero, Flora Doffe, Belén Varela, Victoria Yozzi, José Manuel Verdes, Martina Crispo, Mariela Bollati-Fogolín, Romina Pagotto
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Inflammation is an important process for epithelial barrier protection but when uncontrolled, it can also lead to tissue damage. The nuclear factor-kappa light chain enhancer of activated B cells (NF-κB) signaling pathway is particularly re
Externí odkaz:
https://doaj.org/article/ab485c6d7b7045eebd1f67f198ed64de
Publikováno v:
Briefings in Bioinformatics. 23
Correctly identifying the true driver mutations in a patient’s tumor is a major challenge in precision oncology. Most efforts address frequent mutations, leaving medium- and low-frequency variants mostly unaddressed. For TP53, this identification i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a669e74879a52044eb6872de545ba5
https://doi.org/10.1093/bib/bbab524
https://doi.org/10.1093/bib/bbab524
Publikováno v:
Cancers; Volume 14; Issue 15; Pages: 3559
The recent trend in 3D cell modeling has fostered the emergence of a wide range of models, addressing very distinct goals ranging from the fundamental exploration of cell–cell interactions to preclinical assays for personalized medicine. It is clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7855714bd6f28da34a5df8d2203cff
https://doi.org/10.3390/cancers14153559
https://doi.org/10.3390/cancers14153559
Autor:
Vincent Carbonnier, Flora Doffe, Andreas C. Joerger, Manon Tissier, Šárka Pavlová, Johanna Sofia Margareta Mattsson, Guido Kroemer, Isabelle Martins, Šárka Pospíšilová, B. Leroy, Patrick Micke, Thierry Soussi, Klas G. Wiman, Jana Šmardová
Publikováno v:
Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, 2020, ⟨10.1038/s41418-020-00672-0⟩
Cell Death and Differentiation, 2020, ⟨10.1038/s41418-020-00672-0⟩
Cell Death and Differentiation, Nature Publishing Group, 2020, ⟨10.1038/s41418-020-00672-0⟩
Cell Death and Differentiation, 2020, ⟨10.1038/s41418-020-00672-0⟩
Infrequent and rare genetic variants in the human population vastly outnumber common ones. Although they may contribute significantly to the genetic basis of a disease, these seldom-encountered variants may also be miss-identified as pathogenic if no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60a27c48344e9c52f54370b392c7bea
https://pubmed.ncbi.nlm.nih.gov/33257846
https://pubmed.ncbi.nlm.nih.gov/33257846