Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Flora, Nguyen Van Long"'
Autor:
Michèle Rouleau, Lyne Villeneuve, Eric P. Allain, Jules McCabe-Leroux, Sophie Tremblay, Flora Nguyen Van Long, Ashwini Uchil, Charles Joly-Beauparlant, Arnaud Droit, Chantal Guillemette
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background High expression of the glycosyltransferase UGT2B17 represents an independent adverse prognostic marker in chronic lymphocytic leukemia (CLL). It also constitutes a predictive marker for therapeutic response and a drug resistance m
Externí odkaz:
https://doaj.org/article/c4dc21f5f3f949f4aa203b9c9e894dcd
Autor:
Flora Nguyen Van Long, Délya Valcourt‐Gendron, Patrick Caron, Michèle Rouleau, Lyne Villeneuve, David Simonyan, Trang Le, Roxanne Sergerie, Isabelle Laverdière, Katrina Vanura, Chantal Guillemette
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Background Metabolic dependencies of chronic lymphocytic leukaemia (CLL) cells may represent new personalized treatment approaches in patients harbouring unfavourable features. Methods Here, we used untargeted metabolomics and lipidomics ana
Externí odkaz:
https://doaj.org/article/66f26e0615f245ccb4677cb8f9903257
Autor:
Flora Nguyen Van Long, Audrey Lardy-Cleaud, Dimitri Carène, Caroline Rossoni, Frédéric Catez, Paul Rollet, Nathalie Pion, Déborah Monchiet, Agathe Dolbeau, Marjorie Martin, Valentin Simioni, Susan Bray, Doris Le Beherec, Fernanda Mosele, Ibrahim Bouakka, Amélie Colombe-Vermorel, Laetitia Odeyer, Alexandra Diot, Lee B. Jordan, Alastair M. Thompson, Françoise Jamen, Thierry Dubois, Sylvie Chabaud, Stefan Michiels, Isabelle Treilleux, Jean-Christophe Bourdon, David Pérol, Alain Puisieux, Fabrice André, Jean-Jacques Diaz, Virginie Marcel
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background A current critical need remains in the identification of prognostic and predictive markers in early breast cancer. It appears that a distinctive trait of cancer cells is their addiction to hyperactivation of ribosome biogenesis. T
Externí odkaz:
https://doaj.org/article/fb1de5e1e47048e5883db9d402d40dd4
Autor:
Antoine Wagner, Michèle Rouleau, Lyne Villeneuve, Trang Le, Cheryl Peltier, Éric P. Allain, Caroline Beaudoin, Sophie Tremblay, Fréderic Courtier, Flora Nguyen Van Long, Isabelle Laverdière, Éric Lévesque, Versha Banerji, Katrina Vanura, Chantal Guillemette
Publikováno v:
Cells, Vol 12, Iss 9, p 1295 (2023)
In chronic lymphocytic leukemia (CLL), an elevated glycosyltransferase UGT2B17 expression (UGT2B17HI) identifies a subgroup of patients with shorter survival and poor drug response. We uncovered a mechanism, possibly independent of its enzymatic func
Externí odkaz:
https://doaj.org/article/85e34fb2de6d4a829f62b96745bfae7d
Autor:
Michèle Rouleau, Flora Nguyen Van Long, Véronique Turcotte, Patrick Caron, Louis Lacombe, Armen Aprikian, Fred Saad, Michel Carmel, Simone Chevalier, Eric Lévesque, Chantal Guillemette
Publikováno v:
British Journal of Cancer. 128:285-296
Background Naturally occurring germline gene deletions (KO) represent a unique setting to interrogate gene functions. Complete deletions and differential expression of the human glycosyltransferase UGT2B17 and UGT2B28 genes are linked to prostate can
Autor:
Patrick Caron, Flora Nguyen Van Long, Michèle Rouleau, Emmanuel Bujold, Paul Fortin, Siamak Mohammadi, Éric Lévesque, Sylvie Breton, Chantal Guillemette
Publikováno v:
Journal of chromatography. A. 1677
Nucleotide sugars and more specifically UDP-sugars, represent a major source of energy, key components of extracellular matrix, glycosylation and glucuronidation reactions, and emerge as important signaling molecules through P2Y14 purinergic receptor
Autor:
Flora Nguyen Van Long, Audrey Lardy-Cleaud, Dimitri Carène, Caroline Rossoni, Frédéric Catez, Paul Rollet, Nathalie Pion, Déborah Monchiet, Agathe Dolbeau, Marjorie Martin, Valentin Simioni, Susan Bray, Doris Le Beherec, Fernanda Mosele, Ibrahim Bouakka, Amélie Colombe-Vermorel, Laetitia Odeyer, Alexandra Diot, Lee B. Jordan, Alastair M. Thompson, Françoise Jamen, Thierry Dubois, Sylvie Chabaud, Stefan Michiels, Isabelle Treilleux, Jean-Christophe Bourdon, David Pérol, Alain Puisieux, Fabrice André, Jean-Jacques Diaz, Virginie Marcel
Publikováno v:
BMC Cancer
BMC Cancer, 2022, 22 (1), pp.526. ⟨10.1186/s12885-022-09552-x⟩
BMC Cancer, 2022, 22 (1), pp.526. ⟨10.1186/s12885-022-09552-x⟩
Background A current critical need remains in the identification of prognostic and predictive markers in early breast cancer. It appears that a distinctive trait of cancer cells is their addiction to hyperactivation of ribosome biogenesis. Thus, ribo
Autor:
Bernarda Kazanowska, Flora Nguyen Van Long, Dariusz Wołowiec, Virginie Marcel, Marek Ussowicz, Jean-Jacques Diaz
Publikováno v:
Advances in clinical and experimental medicine : official organ Wroclaw Medical University. 29(1)
Background Dysregulation of ribosome biogenesis and alteration of ribosome composition, including alteration in ribosomal RNA (rRNA) 2'-O-ribose methylation, can play a role in malignant transformation and cancer progression. Several studies recently
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Autor:
Arnaud Pasquer, Jean-Jacques Diaz, Hichem C. Mertani, Jean-Christophe Saurin, Wannapa Sornjai, Flora Nguyen Van Long, Duncan R. Smith, Virginie Marcel, Nathalie Pion
Publikováno v:
Chemico-Biological Interactions. 319:109021
High dietary iron intake is a risk factor for the development of colorectal cancer. However, how iron subsequently impacts the proliferation of colorectal cancer cells remains unclear. This study determined the expression of six iron regulatory genes