Výsledky vyhledávání - "Floor A.A. Ruiter"

Optimization of Media Change Intervals through Hydrogels Using Mathematical Models

Autor: Floor A.A. Ruiter, Jasia King, Sangita Swapnasrita, Stefan Giselbrecht, Roman Truckenmüller, Vanessa L.S. LaPointe, Matthew B. Baker, Aurélie Carlier

Publikováno v: Biomacromolecules. American Chemical Society

Three-dimensional cell culture in engineered hydro gels is increasingly used in tissue engineering and regenerative medicine. The transfer of nutrients, gases, and waste materials through these hydrogels is of utmost importance for cell viability and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508cae773f2fa62f27fa46c21f98bf82
https://doi.org/10.1021/acs.biomac.2c00961

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Soft, Dynamic Hydrogel Confinement Improves Kidney Organoid Lumen Morphology and Reduces Epithelial-Mesenchymal Transition in Culture

Autor: Vanessa L.S. LaPointe, Anika Schumacher, Matthew B. Baker, Gisela G. Slaats, Nadia J. T. Roumans, Floor A.A. Ruiter, Francis L. C. Morgan, Lorenzo Moroni

Publikováno v: Advanced Science, 9(20):2200543. Wiley-VCH Verlag

Pluripotent stem cell-derived kidney organoids offer a promising solution to renal failure, yet current organoid protocols often lead to off-target cells and phenotypic alterations, preventing maturity. Here, various dynamic hydrogel architectures ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf21a8524ab361db14f63b3833be4f5
https://doi.org/10.1002/advs.202200543

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Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition

Autor: Thomas Geuens, Matthew B. Baker, Ton J. Rabelink, Timo Rademakers, Vanessa L.S. LaPointe, Cathelijne W. van den Berg, Francis L. C. Morgan, Loes E. Wiersma, Anika Schumacher, Floor A.A. Ruiter

Publikováno v: Biomaterials, 275:120976. ELSEVIER SCI LTD
Biomaterials, 275. ELSEVIER SCI LTD

Differentiated kidney organoids from induced pluripotent stem cells hold promise as a treatment for patients with kidney diseases. Before these organoids can be translated to the clinic, shortcomings regarding their cellular, extracellular compositio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd6ce49da5ba8189a539e296d77b552
https://doi.org/10.1016/j.biomaterials.2021.120976

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