Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Floor A Harms"'
Autor:
Floor A Harms, Lucia W J M Streng, Mark A Wefers Bettink, Calvin J de Wijs, Luuk H Römers, Rineke Janse, Robert J Stolker, Egbert G Mik
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0278561 (2023)
IntroductionThe newly introduced Cellular Oxygen METabolism (COMET®) monitor enables the measurement of mitochondrial oxygen tension (mitoPO2) using the protoporphyrin IX triplet state lifetime technique (PpIX-TSLT). This study aims to investigate t
Externí odkaz:
https://doaj.org/article/4681521c87c34f02a0b8cf94a2983612
Autor:
Floor A. Harms, Rinse Ubbink, Calvin J. de Wijs, Max P. Ligtenberg, Maarten ter Horst, Egbert G. Mik
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
ObjectiveAdequate oxygenation is essential for the preservation of organ function during cardiac surgery and cardiopulmonary bypass (CPB). Both hypoxia and hyperoxia result in undesired outcomes, and a narrow window for optimal oxygenation exists. Cu
Externí odkaz:
https://doaj.org/article/b4d7a888c56947ba825deb5f071e3d28
Autor:
Lucia W. J. M. Streng, Calvin J. de Wijs, Nicolaas J. H. Raat, Patricia A. C. Specht, Dimitri Sneiders, Mariëlle van der Kaaij, Henrik Endeman, Egbert G. Mik, Floor A. Harms
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1746 (2022)
Mitochondrial dysfunction has been linked to disease progression in COVID-19 patients. This observational pilot study aimed to assess mitochondrial function in COVID-19 patients at intensive care unit (ICU) admission (T1), seven days thereafter (T2),
Externí odkaz:
https://doaj.org/article/07faa7a82c2a48b897ae3563c48de6cc
Autor:
Mik, Rinse Ubbink, Lucia W. J. M. Streng, Nicolaas J. H. Raat, Floor A. Harms, Peter A. W. te Boekhorst, Robert J. Stolker, Egbert G.
Publikováno v:
Biomedicines; Volume 11; Issue 7; Pages: 1873
In light of the associated risks, the question has been raised whether the decision to give a blood transfusion should solely be based on the hemoglobin level. As mitochondria are the final destination of oxygen transport, mitochondrial parameters ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::905d8b061ed913b4305faa3ab8061a25
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163399 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0159544.].
Externí odkaz:
https://doaj.org/article/94096be8ab894a729badfdcab6c4b874
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159544 (2016)
The protoporphyrin IX-triplet state lifetime technique (PpIX-TSLT) is proposed as a potential clinical non-invasive tool to monitor mitochondrial function. This technique has been evaluated in several animal studies. Mitochondrial respirometry allows
Externí odkaz:
https://doaj.org/article/344ddeff01144a48a30f1ebb2c7e4b0d
Publikováno v:
Current Opinion in Critical Care, 26(3), 289-295. Lippincott Williams & Wilkins
Purpose of review To fully exploit the concept of hemodynamic coherence in resuscitating critically ill one should preferably take into account information about the state of parenchymal cells. Monitoring of mitochondrial oxygen tension (mitoPO2) has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be31a41b419b10fc2963a280dadf1b0
https://hdl.handle.net/1765/130527
https://hdl.handle.net/1765/130527
Autor:
Egbert G. Mik, Nathalie Dollee, G.C. Schoonderwoerd, Nicolaas J. H. Raat, Mark A. Wefers Bettink, Floor A. Harms, Patricia A.C. Specht
Publikováno v:
Mitochondrion, 50, 149-157. Elsevier
Mitochondrial function has been predominantly measured ex vivo. Due to isolation and preservation procedures ex vivo measurements might misrepresent in vivo mitochondrial conditions. Direct measurement of in vivo mitochondrial oxygen tension (mitoPO2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803ad3fc1b17b1347173613516fcfc25
https://doi.org/10.1016/j.mito.2019.11.003
https://doi.org/10.1016/j.mito.2019.11.003
Autor:
Floor A, Harms, Egbert G, Mik
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2277
The protoporphyrin IX-triplet state lifetime technique (PpIX-TSLT) has been proposed by us as a potential clinical noninvasive tool for monitoring mitochondrial function. We have been working on the development of mitochondrial respirometry for monit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8f92ab6df537a294b9bd77ff4e3bafc2
https://pubmed.ncbi.nlm.nih.gov/34080152
https://pubmed.ncbi.nlm.nih.gov/34080152
Autor:
Rinse Ubbink, Egbert G. Mik, Calvin De Wijs, Max Ligtenberg, Maarten ter Horst, Floor A. Harms
Publikováno v:
Frontiers in Medicine, 9:785734. Frontiers Media S.A.
ObjectiveAdequate oxygenation is essential for the preservation of organ function during cardiac surgery and cardiopulmonary bypass (CPB). Both hypoxia and hyperoxia result in undesired outcomes, and a narrow window for optimal oxygenation exists. Cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345793655912ed2101eaa0e9e98923a8
https://doi.org/10.1053/j.jvca.2021.08.067
https://doi.org/10.1053/j.jvca.2021.08.067