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FGF1 induces resistance to chemotherapy in ovarian granulosa tumor cells through regulation of p53 mitochondrial localization

Autor: Manousakidi, Sevasti, Guillaume, Arnaud, Pirou, Caroline, Bouleau, Sylvina, Mignotte, Bernard, Renaud, Flore, Floch, Nathalie

Publikováno v: Oncogenesis, Vol 7, Iss 2, Pp 1-13 (2018)
Oncogenesis
Oncogenesis, Nature Publishing Group: Open Access Journals-Option C, 2018, ⟨10.1038/s41389-018-0033-y⟩

International audience; Ovarian cancer remains associated with a high mortality rate and relapse is too frequently seen after chemotherapeutic treatment of granulosa cell tumors (GCTs) or epithelial ovarian cancers (EOCs). It is thus of major importa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::12098fcaf2f2c5cfce6597c500a17e3a
http://link.springer.com/article/10.1038/s41389-018-0033-y

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Evidence for a mitochondrial localization of the retinoblastoma protein

Autor: Oliver Lisa, Rincheval Vincent, Rodríguez-Enfedaque Aida, Bergeaud Marie, Le Floch Nathalie, Ferecatu Ioana, Vallette François M, Mignotte Bernard, Vayssière Jean-Luc

Publikováno v: BMC Cell Biology, Vol 10, Iss 1, p 50 (2009)

Abstract Background The retinoblastoma protein (Rb) plays a central role in the regulation of cell cycle, differentiation and apoptosis. In cancer cells, ablation of Rb function or its pathway is a consequence of genetic inactivation, viral oncoprote

Externí odkaz: https://doaj.org/article/4892b095e5ce4762b97459e40062f3c0

Mitochondrial p53 mediates a transcription-independent regulation of cell respiration and interacts with the mitochondrial F₁F₀-ATP synthase

Autor: Bergeaud, Marie, Mathieu, Lise, Guillaume, Arnaud, Moll, Ute, Mignotte, Bernard, Le Floc'h, Nathalie, Vayssière, Jean-Luc, Rincheval, Vincent, Le Floch, Nathalie

Publikováno v: Cell Cycle
Cell Cycle, Taylor & Francis, 2014, 12 (17), pp.2781-2793. ⟨10.4161/cc.25870⟩

International audience; We and others previously reported that endogenous p53 can be located at mitochondria in the absence of stress, suggesting that p53 has a role in the normal physiology of this organelle. The aim of this study was to characteriz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8152a2596cd4667293157bbd4beb873
https://hal.archives-ouvertes.fr/hal-01871462