Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fleur Chapus"'
Autor:
Maria Guadalupe Martinez, Emmanuel Combe, Aurore Inchauspe, Philippe Emmanuel Mangeot, Elodie Delberghe, Fleur Chapus, Gregory Neveu, Antoine Alam, Kara Carter, Barbara Testoni, Fabien Zoulim
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Chronic hepatitis B virus (HBV) infection persists due to the lack of therapies that effectively target the HBV covalently closed circular DNA (cccDNA). We used HBV-specific guide RNAs (gRNAs) and CRISPR-Cas9 and determined the fate of cccDN
Externí odkaz:
https://doaj.org/article/4c4d851f838140d9933019390e95ad34
Publikováno v:
Hepatitis B Virus and Liver Disease ISBN: 9789811636141
Hepatitis B virus (HBV) is the prototypic member of Orthohepadnaviridae, hepadnaviruses that can lead to transient or persistent infection. When left untreated, chronic HBV infection leads to severe liver damage culminating in hepatocellular carcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43f7de793d0d17745c5ea250d2847f1c
https://doi.org/10.1007/978-981-16-3615-8_1
https://doi.org/10.1007/978-981-16-3615-8_1
Autor:
Peter A C Wing, Jack Ferguson, Xiaodong Zhuang, Sophia Begum, Barbara Testoni, Fleur Chapus, Jane A. McKeating, Guillaume Giraud, James M. Harris, Peter Balfe, Valentina D'Arienzo, Joanna L Parish, Adam Claydon
Publikováno v:
Cellular microbiology
Hepatitis B virus (HBV) infection is of global importance with over 2 billion people exposed to the virus during their lifetime and at risk of progressive liver disease, cirrhosis and hepatocellular carcinoma. HBV is a member of the hepadnaviridae fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e528a1c8b0af3c0f883f73f02fc81e8
https://pubmed.ncbi.nlm.nih.gov/33006186
https://pubmed.ncbi.nlm.nih.gov/33006186
Autor:
Michel Rivoire, Fleur Chapus, Audrey Diederichs, Antoine Alam, Laurent Fraisse, Kara Carter, Barbara Testoni, Bernd Stadelmayer, Fabien Zoulim, Gregory Neveu
Publikováno v:
Journal of Hepatology
Journal of Hepatology, Elsevier, 2020, 73, pp.40-51. ⟨10.1016/j.jhep.2020.01.028⟩
Journal of Hepatology, Elsevier, 2020, 73, pp.40-51. ⟨10.1016/j.jhep.2020.01.028⟩
Background & Aims Covalently closed circular DNA (cccDNA) is the episomal form of the HBV genome that stably resides in the nucleus of infected hepatocytes. cccDNA is the template for the transcription of 6 major viral RNAs, i.e. preC, pg, preS1/2, S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40503f626b927b465b61404951e3619
https://hal.archives-ouvertes.fr/hal-03490308
https://hal.archives-ouvertes.fr/hal-03490308
Publikováno v:
Molecular Biology of the Cell
High-throughput Histone Mapping (HiHiMap) is an automated high-throughput imaging technique to determine histone and histone PTMs across the cell cycle at the single-cell level in a highly parallel format. The method is widely applicable to the syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de650b29cf91b4261f5e91a28f05ba4c
http://europepmc.org/articles/PMC5555657
http://europepmc.org/articles/PMC5555657
Autor:
Maria Guadalupe Martinez, Aurore Inchauspe, Elodie Delberghe, Fleur Chapus, Gregory Neveu, Antoine Alam, Kara Carter, Barbara Testoni, Fabien Zoulim
Publikováno v:
Journal of Hepatology. 73:S841-S842
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0738023b87f6886a6dfd9916e3152402
https://doi.org/10.1016/s0168-8278(20)32126-7
https://doi.org/10.1016/s0168-8278(20)32126-7
Post-translational modifications (PTM) of histone proteins are critical determinants of genome function. Analysis of histone PTM levels has traditionally been performed using biochemical bulk methods to measure individual modifications. These approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e30a5d05c0a1855551d88b3a69f5f27
Publikováno v:
Journal of Hepatology. 68:S762
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ab08a6e938c528d12f8f222f20d7e58
https://doi.org/10.1016/s0168-8278(18)31788-4
https://doi.org/10.1016/s0168-8278(18)31788-4
Autor:
Audrey Diederichs, Sarah Maadadi, J. Walther, Fleur Chapus, H. Meistermann, Souphalone Luangsay, A.J. Muelle-Breckenridge, Jitao David Zhang, D. Avila, Fabien Zoulim, C. Bieniossek, Judith Fresquet, Barbara Testoni, John A. T. Young, M. Locatelli
Publikováno v:
Journal of Hepatology. 68:S776
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d0bd8de02ab9f94d2ba8aa3698b1381
https://doi.org/10.1016/s0168-8278(18)31819-1
https://doi.org/10.1016/s0168-8278(18)31819-1