The OREGANO knowledge graph for computational drug repurposing

Autor: Marina Boudin, Gayo Diallo, Martin Drancé, Fleur Mougin

Publikováno v: Scientific Data, Vol 10, Iss 1, Pp 1-13 (2023)

Abstract Drug repositioning is a faster and more affordable solution than traditional drug discovery approaches. From this perspective, computational drug repositioning using knowledge graphs is a very promising direction. Knowledge graphs constructe

Externí odkaz: https://doaj.org/article/4dd43d8f15f7409e9cfd95f711ddc111

Inclusive Digital Health

Autor: Fleur Mougin, Kate Fultz Hollis, Lina F. Soualmia

Publikováno v: Yearbook of Medical Informatics. 31:002-006

Objectives: To introduce the 2022 International Medical Informatics Association (IMIA) Yearbook by the editors. Methods: The editorial provides an introduction and overview to the 2022 IMIA Yearbook whose special topic is “Inclusive Digital Health:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae33067d264ceaa2159510293e89304
https://doi.org/10.1055/s-0042-1742540

Evaluating the Relevance of Virtual Drugs

Autor: Yvon K. Awuklu, Vianney Jouhet, Sébastien Cossin, Frantz Thiessard, Romain Griffier, Fleur Mougin

Publikováno v: Studies in Health Technology and Informatics
Studies in Health Technology and Informatics, IOS Press, 2022, 294, pp.322-326. ⟨10.3233/shti220467⟩
Studies in Health Technology and Informatics, IOS Press, 2022, Challenges of Trustable AI and Added-Value on Health, 294, pp.322-326. ⟨10.3233/shti220467⟩

International audience; Information about drugs is numerous and varied, and many drugs can share the same information. Grouping drugs that have common characteristics can be useful to avoid redundancy and facilitate interoperability. Our work focused

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f98c62caf450f28e920a490d047632a
https://pubmed.ncbi.nlm.nih.gov/35612085

Data Element Mapping in the Data Privacy Era

Autor: Romain, Griffier, Sébastien, Cossin, François, Konschelle, Fleur, Mougin, Vianney, Jouhet

Publikováno v: Studies in health technology and informatics. 294

Secondary use of health data is made difficult in part because of large semantic heterogeneity. Many efforts are being made to align local terminologies with international standards. With increasing concerns about data privacy, we focused here on the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::15cd734ef1d97a227426545399a38d2b
https://pubmed.ncbi.nlm.nih.gov/35612087

Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data

Autor: Chloe I Bloom, Jacques Banchereau, Mohamed Alfaki, J. Theodore Phillips, Asuncion Mejias, Octavio Ramilo, Karolina Palucka, Laurent Chiche, Farrah Kheradmand, Noémie Jourde-Chiche, Matthew C. Altman, Fleur Mougin, Davide Bedognetti, Marc Lipman, Christine M. Graham, Nicole Baldwin, Mathieu Garand, Patricia Thebault, Scott R. Presnell, Basirudeen Syed Ahamed Kabeer, Darawan Rinchai, Goran B. Klintmalm, Matthew Berry, Ganjana Lertmemongkolchai, Prasong Khaenam, Robert J. Wilkinson, Rodolphe Thiébaut, Damien Chaussabel, Virginia Pascual, Aaron Ayllon-Benitez, Anne O'Garra, Mohammed Toufiq, Elizabeth Whalen

Publikováno v: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-24584-w⟩
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-24584-w⟩

As the capacity for generating large-scale molecular profiling data continues to grow, the ability to extract meaningful biological knowledge from it remains a limitation. Here, we describe the development of a new fixed repertoire of transcriptional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a19e909858b6ecfe874dd28657fdb8
http://europepmc.org/articles/PMC8289976