Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Fletcher F, Hahn"'
Autor:
Lance Price, Candice C. Clay, Kevin S. Harrod, Jesse Van Westrienen, Fletcher F. Hahn, Jennifer Knight, Nathan Donart, Ndingsa Fomukong, Wanli Lei
Publikováno v:
Journal of Virology
Our knowledge regarding immune-protective and immunopathogenic events in severe acute respiratory syndrome coronavirus (SARS-CoV) infection is limited, and little is known about the dynamics of the immune response at the primary site of disease. Here
Publikováno v:
Health Physics. 99:363-366
The stochastic effects in the lung of inhaled, insoluble particles of alpha- and beta-emitting particles and low-linear energy transfer (LET) thoracic irradiation were compared in rats using data from previously conducted studies. Male and female F34
Autor:
Joe L. Mauderly, Fletcher F. Hahn, Steven K. Seilkop, Raymond A. Guilmette, Bruce A. Muggenburg, Bruce B. Boecker, J. H. Diel
Publikováno v:
Radiation Research. 170:736-757
Beagle dogs inhaled graded exposure levels of insoluble plutonium dioxide ((239)PuO(2)) aerosols in one of three monodisperse particle sizes at the Lovelace Respiratory Research Institute (LRRI) to study the life-span health effects of different degr
Publikováno v:
International Journal of Toxicology. 26:307-313
In the past several years an increased number of lung tumors has been reported in laboratory studies of rats and mice after lifetime exposure to mainstream cigarette smoke. Proliferative epithelial lesions are present in the lungs of both species and
Publikováno v:
Toxicologic Pathology. 35:136-147
Environmental factors play a major role in a majority of lung diseases. Asthma, chronic obstructive pulmonary disease (COPD), lung cancer, and many interstitial lung diseases are influenced or caused by environmental factors. Animals and humans may r
Autor:
Amie K. Lund, Kunio Nagashima, Matthew J. Campen, Patsy Y. Cossey, Vernon E. Walker, Fletcher F. Hahn, Rao L. Divi, Miriam C. Poirier, Dale M. Walker, Dennis L. Cook
Publikováno v:
Cardiovascular Toxicology. 4:133-154
Cardiac toxicity has been associated with HIV infection and exposure to nucleoside reverse transcriptase inhibitors (NRTIs), but the role of the latter in the development of cardiac disease of HIV-infected patients is uncertain. To investigate the ca
Publikováno v:
Environmental Health Perspectives
In this study, we determined the carcinogenicity of depleted uranium (DU) metal fragments containing 0.75% titanium in muscle tissues of rats. The results have important implications for the medical management of Gulf War veterans who were wounded wi
Autor:
Jesse Van Westrienen, Jennifer L. Tipper, Fletcher F. Hahn, Katie Overheim, Candice C. Clay, Ndingsa Fomukong, Jennifer Knight, Kevin S. Harrod, Nathan Donart
Publikováno v:
Immunity & Ageing
Immunity & ageing, 11(1):4
Immunity & Ageing : I & A
Immunity & ageing, 11(1):4
Immunity & Ageing : I & A
Background Many respiratory viruses disproportionately impact the elderly. Likewise, advanced age correlated with more adverse disease outcomes following severe acute respiratory syndrome coronavirus (SARS-CoV) infection in humans. We used an aged Af
Publikováno v:
Environmental Health Perspectives
Differences among species in the anatomic sites of particle retention could influence responses to inhaled particles. In this study, we used morphometric techniques to examine the influence of exposure concentration on particle retention in histologi
Autor:
Thomas H. March, C. H. Hobbs, Fletcher F. Hahn, Gregory L. Finch, Edward B. Barr, Margaret G Ménache, Kristen J. Nikula
Publikováno v:
Toxicological Sciences. 51:289-299
Cigarette smoke (CS) causes pulmonary emphysema in humans, but results of previous studies on CS-exposed laboratory animals have been equivocal and have not clearly demonstrated progression of the disease. In this study, morphometry and histopatholog