Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Fletcher, HA"'
Autor:
Müller, J, Tanner, R, Matsumiya, M, Snowden, MA, Landry, B, Satti, I, Harris, SA, O'Shea, MK, Stockdale, L, Marsay, L, Chomka, A, Harrington-Kandt, R, Manjaly Thomas, Z-R, Stylianou, E, Naranbhai, V, Mbandi, SK, Hatherill, M, Hussey, G, Mahomed, H, Tameris, M, McClain, JB, Hanekom, WA, Evans, TG, Scriba, TJ, McShane, H, Fletcher, HA
Publikováno v:
JCI Insight. 4(23)
Immune activation is associated with increased risk of tuberculosis (TB) disease in infants. We performed a case control analysis to identify drivers of immune activation and disease risk. Among 49 infants who developed TB disease over the first two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::fc56f3edada05d1152ddc04e20c984f7
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Fletcher, HA, Filali-Mouhim, A, Nemes, E, Hawkridge, A, Keyser, A, Njikan, S, Hatherill, M, Scriba, TJ, Abel, B, Kagina, BM, Veldsman, A, Agudelo, NM, Kaplan, G, Hussey, GD, Sekaly, R-P, Hanekom, WA, BCG study team, McShane, H
Publikováno v:
BMC Medicine
Background An incomplete understanding of the immunological mechanisms underlying protection against tuberculosis (TB) hampers the development of new vaccines against TB. We aimed to define host correlates of prospective risk of TB disease following
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a7c55ad23fcf920e6605e348b0776a
https://ora.ox.ac.uk/objects/uuid:ca024b02-1d1b-4e0b-a9d7-f935669fe3a7
https://ora.ox.ac.uk/objects/uuid:ca024b02-1d1b-4e0b-a9d7-f935669fe3a7
Autor:
Matsumiya, M, Satti, I, Chomka, A, Harris, SA, Stockdale, L, Meyer, J, Fletcher, HA, Mcshane, H
Publikováno v:
The Journal of Infectious Diseases
Background: Bacillus Calmette-Guerin (BCG) vaccine is the most widely administered vaccine in the world, yet its mechanism of action remains unclear. We hypothesize that certain immune pathways are associated with reduced mycobacterial growth followi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::274a9efb0667beecff576a9b82420cf6
http://europepmc.org/articles/PMC4392868
http://europepmc.org/articles/PMC4392868
Autor:
Vainieri, ML, Blagborough, AM, MacLean, AL, Haltalli, ML, Ruivo, N, Fletcher, HA, Stumpf, MP, Sinden, R, Celso, CL
Publikováno v:
Open Biology, Vol 6, Iss 6 (2016)
Open Biology
Open Biology
Haematopoiesis is the complex developmental process that maintains the turnover of all blood cell lineages. It critically depends on the correct functioning of rare, quiescent haematopoietic stem cells (HSCs) and more numerous, HSC-derived, highly pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5ffd2198521e49b0fb27cd21e81778bd
http://hdl.handle.net/10044/1/33612
http://hdl.handle.net/10044/1/33612
Autor:
Harris, SA, Satti, I, Matsumiya, M, Stockdale, L, Chomka, A, Tanner, R, O'Shea, MK, Thomas, Z-R, Tameris, M, Mahomed, H, Scriba, TJ, Hanekom, WA, Fletcher, HA, McShane, H
Publikováno v:
Clinical and Vaccine Immunology : CVI
The first phase IIb safety and efficacy trial of a new tuberculosis vaccine since that for BCG was completed in October 2012. BCG-vaccinated South African infants were randomized to receive modified vaccinia virus Ankara, expressing the Mycobacterium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e7a8756c8bc481dfaf28941f7c11a0d9
http://ora.ox.ac.uk/objects/uuid:325a4ed8-622c-436f-bd16-2d5260cc8c92
http://ora.ox.ac.uk/objects/uuid:325a4ed8-622c-436f-bd16-2d5260cc8c92
Autor:
Harris, SA, Meyer, J, Satti, I, Marsay, L, Poulton, ID, Tanner, R, Minassian, AM, Fletcher, HA, Mcshane, H
Publikováno v:
The Journal of Infectious Diseases
Background. A new vaccine is urgently needed to combat tuberculosis. However, without a correlate of protection, selection of the vaccines to take forward into large-scale efficacy trials is difficult. Use of bacille Calmette-Guérin (BCG) as a surro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::259cdbf2e8b299e48e19e159124daddc
https://researchonline.lshtm.ac.uk/id/eprint/1367749/1/jit647.pdf
https://researchonline.lshtm.ac.uk/id/eprint/1367749/1/jit647.pdf
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