The DnaA Tale

Autor: Flemming G. Hansen, Tove Atlung

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)

More than 50 years have passed since the presentation of the Replicon Model which states that a positively acting initiator interacts with a specific site on a circular chromosome molecule to initiate DNA replication. Since then, the origin of chromo

Externí odkaz: https://doaj.org/article/9f662c8468ea452794abc91fee12b2a5

DnaC inactivation in Escherichia coli K-12 induces the SOS response and expression of nucleotide biosynthesis genes.

Autor: Anders Løbner-Olesen, Monika Slominska-Wojewodzka, Flemming G Hansen, Martin G Marinus

Publikováno v: PLoS ONE, Vol 3, Iss 8, p e2984 (2008)

Initiation of chromosome replication in E. coli requires the DnaA and DnaC proteins and conditionally-lethal dnaA and dnaC mutants are often used to synchronize cell populations.DNA microarrays were used to measure mRNA steady-state levels in initiat

Externí odkaz: https://doaj.org/article/3900730b3888448099533e06f8bc1d8f

The MG1363 and IL1403 Laboratory Strains of Lactococcus lactis and Several Dairy Strains Are Diploid

Autor: Ole Michelsen, Flemming G. Hansen, Peter Ruhdal Jensen, Bjarne Albrechtsen

Publikováno v: Journal of Bacteriology. 192:1058-1065

Bacteria are normally haploid, maintaining one copy of their genome in one circular chromosome. We have examined the cell cycle of laboratory strains of Lactococcus lactis , and, to our surprise, we found that some of these strains were born with two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c333269174c5311acec32c4f69ae7e
https://doi.org/10.1128/jb.00900-09

Segregation of chromosome arms in growing and non-growing Escherichia coli cells

Autor: Flemming G. Hansen, Norbert O. E. Vischer, Tove Atlung, Conrad L. Woldringh

Publikováno v: Woldringh, C L, Hansen, F G, Vischer, N O E & Atlung, T 2015, ' Segregation of chromosome arms in growing and non-growing Escherichia coli cells ', Frontiers in Microbiology, vol. 6, 448 . https://doi.org/10.3389/fmicb.2015.00448
Frontiers in Microbiology, Vol 6 (2015)
Frontiers in Microbiology

In slow-growing Escherichia coli cells the chromosome is organized with its left (L) and right (R) arms lying separated in opposite halves of the nucleoid and with the origin (0) in-between, giving the pattern L-O-R. During replication one of the arm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff9c06b31db5eff3f69ea3b3c710c6e
https://orbit.dtu.dk/en/publications/43eca367-d55e-49de-9447-d50efdbaa6b8

Progressive segregation of the Escherichia coli chromosome

Autor: Yongfang Li, Brenda Youngren, Henrik Jørck Nielsen, Flemming G. Hansen, Stuart Austin

Publikováno v: Molecular Microbiology. 61:383-393

We have followed the fate of 14 different loci around the Escherichia coli chromosome in living cells at slow growth rate using a highly efficient labelling system and automated measurements. Loci are segregated as they are replicated, but with a mar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2194680567b977fd18c8080896f47344
https://doi.org/10.1111/j.1365-2958.2006.05245.x