Discovery and clinical translation of ceperognastat, an O‐GlcNAcase (OGA) inhibitor, for the treatment of Alzheimer's disease.

Autor: Kielbasa, William, Goldsmith, Paul, Donnelly, Kevin B., Nuthall, Hugh N., Shcherbinin, Sergey, Fleisher, Adam S., Hendle, Jörg, DuBois, Susan L., Lowe, Stephen L., Zhang, Feiyu Fred, Woerly, Eric M., Dreyfus, Nicolas J.‐F., Evans, David, Gilmore, Jeremy, Mancini, Michele, Constantinescu, Cristian C., Gunn, Roger N., Russell, David S., Collins, Emily C., Brys, Miroslaw

Publikováno v: Alzheimer's & Dementia: Translational Research & Clinical Interventions; Oct2024, Vol. 10 Issue 4, p1-10, 10p

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Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

Autor: Mattsson, Niklas ^{a, ∗}, Groot, Colin ^b, Jansen, Willemijn J. ^c, Landau, Susan M. ^d, Villemagne, Victor L. ^e, Engelborghs, Sebastiaan ^f, Mintun, Mark M. ^g, Lleo, Alberto ^h, Molinuevo, José Luis ⁱ, Jagust, William J. ^d, Frisoni, Giovanni B. ^{j, k}, Ivanoiu, Adrian ^l, Chételat, Gaël ^m, Resende de Oliveira, Catarina ⁿ, Rodrigue, Karen M. ^o, Kornhuber, Johannes ^p, Wallin, Anders ^q, Klimkowicz-Mrowiec, Aleksandra ^r, Kandimalla, Ramesh ^s, Popp, Julius ^t, Aalten, Pauline P. ^c, Aarsland, Dag ^u, Alcolea, Daniel ^h, Almdahl, Ina S. ^v, Baldeiras, Inês ⁿ, van Buchem, Mark A. ^w, Cavedo, Enrica ^{k, x}, Chen, Kewei ^y, Cohen, Ann D. ^z, Förster, Stefan ^aa, Fortea, Juan ^h, Frederiksen, Kristian S. ^bb, Freund-Levi, Yvonne ^cc, Gill, Kiran Dip ^s, Gkatzima, Olymbia ^dd, Grimmer, Timo ^ee, Hampel, Harald ^{x, ff}, Herukka, Sanna-Kaisa ^gg, Johannsen, Peter ^hh, van Laere, Koen ⁱⁱ, de Leon, Mony J. ^jj, Maier, Wolfgang ^kk, Marcusson, Jan ^ll, Meulenbroek, Olga ^mm, Møllergård, Hanne M. ^v, Morris, John C. ⁿⁿ, Mroczko, Barbara ^oo, Nordlund, Arto ^q, Prabhakar, Sudesh ^pp, Peters, Oliver ^qq, Rami, Lorena ⁱ, Rodríguez-Rodríguez, Eloy ^rr, Roe, Catherine M. ⁿⁿ, Rüther, Eckart ^ss, Santana, Isabel ⁿ, Schröder, Johannes ^tt, Seo, Sang W. ^uu, Soininen, Hilkka ^gg, Spiru, Luiza ^vv, Stomrud, Erik ^a, Struyfs, Hanne ^f, Teunissen, Charlotte E. ^ww, Verhey, Frans R.J. ^c, Vos, Stephanie J.B. ^c, van Waalwijk van Doorn, Linda J.C. ^{xx, yy}, Waldemar, Gunhild ^bb, Wallin, Åsa K. ^a, Wiltfang, Jens ^{ss, zz}, Vandenberghe, Rik ^aaa, Brooks, David J. ^bbb, Fladby, Tormod ^v, Rowe, Christopher C. ^e, Drzezga, Alexander ^ccc, Verbeek, Marcel M. ^{xx, yy}, Sarazin, Marie ^ddd, Wolk, David A. ^eee, Fleisher, Adam S. ^{y, fff, ggg}, Klunk, William E. ^z, Na, Duk L. ^uu, Sánchez-Juan, Pascual ^rr, Lee, Dong Young ^hhh, Nordberg, Agneta ⁱⁱⁱ, Tsolaki, Magda ^dd, Camus, Vincent ^jjj, Rinne, Juha O. ^kkk, Fagan, Anne M. ⁿⁿ, Zetterberg, Henrik ^{lll, mmm, nnn, ooo}, Blennow, Kaj ^{nnn, ooo}, Rabinovici, Gil D. ^ppp, Hansson, Oskar ^a, van Berckel, Bart N.M. ^qqq, van der Flier, Wiesje M. ^{b, rrr}, Scheltens, Philip ^b, Visser, Pieter Jelle ^{b, c}, Ossenkoppele, Rik ^{a, b, qqq, ∗∗}

Publikováno v: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association July 2018 14(7):913-924

Topographic staging of tau positron emission tomography images

Autor: Schwarz, Adam J. ^{a, b, c, ∗}, Shcherbinin, Sergey ^a, Slieker, Lawrence J. ^a, Risacher, Shannon L. ^{b, d}, Charil, Arnaud ^a, Irizarry, Michael C. ^a, Fleisher, Adam S. ^a, Southekal, Sudeepti ^e, Joshi, Abhinay D. ^e, Devous, Michael D., Sr. ^e, Miller, Bradley B. ^a, Saykin, Andrew J. ^{b, d}

Publikováno v: In Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 2018 10:221-231

The Role of Neuroimaging in the Assessment of the Cognitively Impaired Elderly

Autor: Kollack-Walker, Sara ^{a, ∗}, Liu, Collin Y. ^b, Fleisher, Adam S. ^c

Publikováno v: In Neurologic Clinics May 2017 35(2):231-262