Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Fleischmann Wr"'
Autor:
Georgiades Ja, Fleischmann Wr
Publikováno v:
Biotherapy (Dordrecht, Netherlands)
Summary A number of different laboratories reported on studies with orally administered interferons and cytokines. Their observations extend previous observations which showed that orally administered interferons and cytokines can exert both local an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fb27c15ce8ba47cbeb6627d88acdeb
https://doi.org/10.1007/bf01877206
https://doi.org/10.1007/bf01877206
Autor:
Fleischmann Wr, Srecko Koren
Publikováno v:
Journal of Interferon Research. 14:343-347
Interferons alpha, beta, and gamma have been shown to exert systemic effects following their oral administration to mice. It was of importance to determine whether oral administration of another biologic response modifier, interleukin-2 (IL-2), could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70306fb159d3f9fbc33f4bc2267a8761
https://doi.org/10.1089/jir.1994.14.343
https://doi.org/10.1089/jir.1994.14.343
Publikováno v:
Anti-Cancer Drugs. 5:53-56
In this study, we tried to define in vitro interactions of two antitumor agents that have different sites and different mechanisms of action. Vinblastine (VLB) in combination with human recombinant interferon-alpha A/D (rHuIFN-alpha A/D) and in combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7de1832acb03f1db17282a7d9cb4b09
https://doi.org/10.1097/00001813-199402000-00008
https://doi.org/10.1097/00001813-199402000-00008
Autor:
Gary R. Klimpel, Dorian H. Coppenhaver, G J Stanton, Stephen K. Tyring, Thomas K. Hughes, Fleischmann Wr, Samuel Baron, David W. Niesel
Publikováno v:
JAMA: The Journal of the American Medical Association. 266:1375-1383
The interferons (IFN) are one of the body's natural defensive responses to such foreign components as microbes, tumors, and antigens. The IFN response begins with the production of the IFN proteins (α, β, and γ), which then induce the antiviral, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f489d3a91e852ec3346809afc11c9f85
https://doi.org/10.1001/jama.266.10.1375
https://doi.org/10.1001/jama.266.10.1375
Publikováno v:
Experimental Biology and Medicine. 197:424-430
The ability of interferons (IFN) to exert a systemic effect following their oral administration was evaluated. One systemic effect of parenteral interferon administration has been shown to be a suppression of the number of peripheral white blood cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b0801ce4691902fdd2ce29cd9d8dd1
https://doi.org/10.3181/00379727-197-43277
https://doi.org/10.3181/00379727-197-43277
Publikováno v:
Cancer immunology, immunotherapy : CII. 39(3)
Mouse B16 melanoma cells rapidly develop resistance to the antiproliferative effects of interferon alpha (IFN alpha) and interferon beta (IFN beta) when they are exposed to the interferons in vitro. This resistance was characterized to be non-genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069a7dc32dd2705f2055b19294a46d87
https://pubmed.ncbi.nlm.nih.gov/7923244
https://pubmed.ncbi.nlm.nih.gov/7923244
Autor:
Fleischmann Wr, Koren S
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 204(2)
The accepted routes of interferon (IFN) administration in clinical applications are intramuscular, subcutaneous, intraperitoneal, intratumor, and intravenous. Recently, oral administration of interferons has been shown to cause a suppression of perip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e98369d59a10bf61d75de32a68ca1f
https://pubmed.ncbi.nlm.nih.gov/8415770
https://pubmed.ncbi.nlm.nih.gov/8415770
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 201(2)
Interferons (IFN) have been approved for a number of clinical uses. The accepted routes of administration are intramuscular, subcutaneous, and intravenous. Recently, interferons administered by the oral route have been shown to exert a systemic effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8271fdf898fe6696b8771d2f4b336ce3
https://pubmed.ncbi.nlm.nih.gov/1384066
https://pubmed.ncbi.nlm.nih.gov/1384066
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