Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Fleischman RW"'
Publikováno v:
Toxicology. 13:263-273
Summary The toxic effects of Adriamycin were studied following i.v. administration of from 10.0 mg/kg to 0.039 mg/kg (200—0.780 mg/m 2 ) to beagle dogs, and from 5.83 mg/kg to 0.625 mg/kg (49.9—7.5 mg/m 2 ) in rhesus monkeys by a variety of short
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4b098fe176be9a03fe1e84e2be678c2
https://doi.org/10.1016/s0300-483x(79)80030-x
https://doi.org/10.1016/s0300-483x(79)80030-x
Autor:
Fleischman Rw, Phelan R, George R. Thompson, Ruth D. Davis, Ulrich Schaeppi, V. Jliewski, Stanley W. Stadnicki, Cooney Da
Publikováno v:
Toxicology and Applied Pharmacology. 18:841-850
Phenester [acetic acid, (p-(bis (2 chlorethyl)-amino)-phenyl) ethyl ester] is known to produce marked oncolytic activity against the mammary adenocarcinoma 13,762 in rats. For evaluation of toxicity, 17 dogs were treated with single doses of 120, 80,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9804fa11707d27e0d1bf310c30ca2e3e
https://doi.org/10.1016/0041-008x(71)90232-8
https://doi.org/10.1016/0041-008x(71)90232-8
Autor:
Ruth D. Davis, Harris Rosenkrantz, Ulrich Schaeppi, George R. Thompson, Cooney Da, Fleischman Rw, John R. Baker
Publikováno v:
Toxicology and Applied Pharmacology. 22:544-555
Bleomycin, a potent antitumor antibiotic obtained from Streptomyces verticillus , was administered to 14 dogs at doses from 0.312 to 5.0 mg/kg iv every 4 days for 6 to 28 wk. The resultant toxicity was atypical for most antitumor agents. Nondose-rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e108dd510271f85141618b3632e6df49
https://doi.org/10.1016/0041-008x(72)90283-9
https://doi.org/10.1016/0041-008x(72)90283-9
Publikováno v:
Toxicology. 12(1)
Chlorozotocin was studied for toxic effects in beagle dogs and rhesus monkeys. The results are the subject of this report. The compound was administered i.v. as single and 5 daily doses in dogs and monkeys; and, in dogs, as 10 consecutive daily doses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f1cbe5c52a92ffc94084684224e513
https://pubmed.ncbi.nlm.nih.gov/157561
https://pubmed.ncbi.nlm.nih.gov/157561
Publikováno v:
Toxicology. 4(1)
Subcutaneous (s.c.) administration of delta-9-tetrahydrocannabinol (delta-9-THC) to rabbits produced dose-related cumulative toxicity. Five groups of three New Zealand albino rabbits each received 28 daily treatments with isotonic saline, sesame oil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7871c2ed900ab2c6aab96b4ac609db3
https://pubmed.ncbi.nlm.nih.gov/1129806
https://pubmed.ncbi.nlm.nih.gov/1129806
Autor:
Fleischman Rw, Henry J. Esber, Y.K. Luthra, Miasnig Hagopian, E.J. Gralla, J.R. Baker, W. Marcus
Publikováno v:
Toxicology and applied pharmacology. 40(2)
Hexachlorobenzene (HCB) was administered daily in gelatin capsules to male and female beagles at 1000, 100, 10, and 1 mg/dog for 12 months. Mortality, anorexia, and weight loss occurred at the highest and, to a lesser degree, at the next lower dose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2942caf1e9b3f502f1970b08f4b3073
https://pubmed.ncbi.nlm.nih.gov/877958
https://pubmed.ncbi.nlm.nih.gov/877958
Autor:
Fleischman RW
Publikováno v:
Veterinary medicine, small animal clinician : VM, SAC [Vet Med Small Anim Clin] 1981 Jul; Vol. 76 (7), pp. 1006-7.
Autor:
Fleischman RW, McCracken D
Publikováno v:
Veterinary pathology [Vet Pathol] 1977 Jul; Vol. 14 (4), pp. 387-91.
Publikováno v:
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1975 May; Vol. 32 (2), pp. 399-417.
Publikováno v:
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1977 May; Vol. 40 (2), pp. 227-39.