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pro vyhledávání: '"Flegg Jennifer A"'
In the infectious disease literature, significant effort has been devoted to studying dynamics at a single scale. For example, compartmental models describing population-level dynamics are often formulated using differential equations. In cases where
Externí odkaz:
http://arxiv.org/abs/2406.05058
Autor:
Anwar, Md Nurul, McCaw, James M., Zarebski, Alexander E., Hickson, Roslyn I., Flegg, Jennifer A.
Publikováno v:
Epidemics Volume 48 , September 2024, 100789
Plasmodium vivax is the most geographically widespread malaria parasite due to its ability to remain dormant (as a hypnozoite) in the human liver and subsequently reactivate. Given the majority of P. vivax infections are due to hypnozoite reactivatio
Externí odkaz:
http://arxiv.org/abs/2405.20619
Autor:
Germano, Domenic P. J., Zarebski, Alexander E., Hautphenne, Sophie, Moss, Robert, Flegg, Jennifer A., Flegg, Mark B.
Multi-scale systems often exhibit stochastic and deterministic dynamics. Capturing these aspects in a compartmental model is challenging. Notably, low occupancy compartments exhibit stochastic dynamics and high occupancy compartments exhibit determin
Externí odkaz:
http://arxiv.org/abs/2405.13239
The epidemiological behavior of Plasmodium vivax malaria occurs across spatial scales including within-host, population, and metapopulation levels. On the within-host scale, P. vivax sporozoites inoculated in a host may form latent hypnozoites, the a
Externí odkaz:
http://arxiv.org/abs/2312.05722
Autor:
Anwar, Md Nurul, Smith, Lauren, Devine, Angela, Mehra, Somya, Walker, Camelia R., Ivory, Elizabeth, Conway, Eamon, Mueller, Ivo, McCaw, James M., Flegg, Jennifer A., Hickson, Roslyn I.
Publikováno v:
Plos Computational Biology 20(3), 2024
Plasmodium vivax is one of the most geographically widespread malaria parasites in the world due to its ability to remain dormant in the human liver as hypnozoites and subsequently reactivate after the initial infection (i.e. relapse infections). Mor
Externí odkaz:
http://arxiv.org/abs/2309.00274
Autor:
Foo, Yong See, Flegg, Jennifer A.
In genetic studies, haplotype data provide more refined information than data about separate genetic markers. However, large-scale studies that genotype hundreds to thousands of individuals may only provide results of pooled data, where only the tota
Externí odkaz:
http://arxiv.org/abs/2308.16465
Geostatistical analysis of health data is increasingly used to model spatial variation in malaria prevalence, burden, and other metrics. Traditional inference methods for geostatistical modelling are notoriously computationally intensive, motivating
Externí odkaz:
http://arxiv.org/abs/2305.01907
Autor:
Anwar, Md Nurul, Hickson, Roslyn I., Mehra, Somya, Price, David J., McCaw, James M., Flegg, Mark B., Flegg, Jennifer A.
\textit{Plasmodium vivax} is the most geographically widespread malaria-causing parasite resulting in significant associated global morbidity and mortality. One of the factors driving this widespread phenomenon is the ability of the parasites to rema
Externí odkaz:
http://arxiv.org/abs/2302.12381
Autor:
Brown, Owen1 (AUTHOR), Flegg, Jennifer A.1 (AUTHOR) jennifer.flegg@unimelb.edu.au, Weiss, Daniel J.2,3 (AUTHOR), Golding, Nick2,3,4 (AUTHOR)
Publikováno v:
Malaria Journal. 10/10/2024, Vol. 23 Issue 1, p1-10. 10p.
Malaria is a vector-borne disease that exacts a grave toll in the Global South. The epidemiology of Plasmodium vivax, the most geographically expansive agent of human malaria, is characterised by the accrual of a reservoir of dormant parasites known
Externí odkaz:
http://arxiv.org/abs/2208.10403