The Pseudo‐Natural Product Rhonin Targets RHOGDI.

Autor: Akbarzadeh, Mohammad^1,2 (AUTHOR), Flegel, Jana¹ (AUTHOR), Patil, Sumersing¹ (AUTHOR), Shang, Erchang¹ (AUTHOR), Narayan, Rishikesh^1,3 (AUTHOR), Buchholzer, Marcel² (AUTHOR), Kazemein Jasemi, Neda S.² (AUTHOR), Grigalunas, Michael¹ (AUTHOR), Krzyzanowski, Adrian^1,4 (AUTHOR), Abegg, Daniel⁵ (AUTHOR), Shuster, Anton⁵ (AUTHOR), Potowski, Marco¹ (AUTHOR), Karatas, Hacer¹ (AUTHOR), Karageorgis, George¹ (AUTHOR), Mosaddeghzadeh, Niloufar² (AUTHOR), Zischinsky, Mia‐Lisa⁶ (AUTHOR), Merten, Christian⁷ (AUTHOR), Golz, Christopher⁴ (AUTHOR), Brieger, Lucas⁴ (AUTHOR), Strohmann, Carsten⁴ (AUTHOR)

Publikováno v: Angewandte Chemie. 4/25/2022, Vol. 134 Issue 18, p1-12. 12p.

Combination of Pseudo‐Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo‐Sesquiterpenoid Alkaloids.

Autor: Liu, Jie^1,2 (AUTHOR), Flegel, Jana^1,2 (AUTHOR), Otte, Felix³ (AUTHOR), Pahl, Axel^1,4 (AUTHOR), Sievers, Sonja^1,4 (AUTHOR), Strohmann, Carsten³ (AUTHOR), Waldmann, Herbert^1,2 (AUTHOR) Herbert.waldmann@mpi-dortmund.mpg.de

Publikováno v: Angewandte Chemie. 9/20/2021, Vol. 133 Issue 39, p21554-21565. 12p.

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Identification and characterization of inhibitors of hedgehog-induced osteoblast differentiation

Autor: Flegel, Jana Erika

Hedgehog (Hh) signaling is one of the major pathways that is essentially required during embryonic development in vertebrates. Dysregulation during embryogenesis has been linked to severe developmental malformations including cyclopia and holoprosenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64eccc6c6af38f7b823cedbc7078389a

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