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Patient and provider perspectives on polygenic risk scores: implications for clinical reporting and utilization.

Autor: Lewis ACF; E.J. Safra Center for Ethics, Harvard University, Cambridge, USA. annalewis@fas.harvard.edu.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. annalewis@fas.harvard.edu., Perez EF; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Mass General Brigham Personalized Medicine, Boston, MA, USA., Prince AER; College of Law, University of Iowa, Iowa City, IA, USA., Flaxman HR; Weill Cornell Medical College, New York City, NY, USA., Gomez L; Mass General Brigham Personalized Medicine, Boston, MA, USA., Brockman DG; Color Health, Burlingame, CA, USA., Chandler PD; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Kerman BJ; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Lebo MS; Mass General Brigham Personalized Medicine, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Smoller JW; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Precision Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Weiss ST; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Channing Division of Network Medicine, Boston, MA, USA., Blout Zawatksy CL; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Population Precision Health, Ariadne Labs, Boston, MA, USA.; The MGH Institute of Health Professions, Boston, MA, USA., Meigs JB; Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA., Green RC; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Population Precision Health, Ariadne Labs, Boston, MA, USA.; Mass General Brigham Personalized Medicine, Cambridge, MA, USA., Vassy JL; Harvard Medical School, Boston, MA, USA.; Population Precision Health, Ariadne Labs, Boston, MA, USA.; Veterans Affairs Boston Healthcare System, Boston, MA, USA.; Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, MA, USA., Karlson EW; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Mass General Brigham Personalized Medicine, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.

Publikováno v: Genome medicine [Genome Med] 2022 Oct 07; Vol. 14 (1), pp. 114. Date of Electronic Publication: 2022 Oct 07.