Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Flavio Moroni"'
Autor:
Mariaconcetta Durante, Silvia Sgambellone, Cecilia Lanzi, Patrizia Nardini, Alessandro Pini, Flavio Moroni, Emanuela Masini, Laura Lucarini
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Pulmonary fibrosis is the most frequent form of interstitial lung disease. Effective therapies are not yet available; novel therapeutic approaches are needed for counteracting fibrosis. Poly(ADP-ribose) polymerases are enzymes, involved in DNA repair
Externí odkaz:
https://doaj.org/article/5c92be04260341febbbfc88a6cf766b6
Autor:
Elisabetta Gerace, Elisa Landucci, Daniele Bani, Flavio Moroni, Guido Mannaioni, Domenico E. Pellegrini-Giampietro
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2019)
Long-term alcohol use can lead to alterations in brain structure and functions and, in some cases, to neurodegeneration. Several mechanisms have been proposed to explain ethanol (EtOH)-related brain injury. One of the most relevant mechanisms of alco
Externí odkaz:
https://doaj.org/article/7613ccd93df349f7bb233453f0f4eda6
Autor:
Giuseppe Faraco, Maria Pittelli, Leonardo Cavone, Silvia Fossati, Marco Porcu, Paolo Mascagni, Gianluca Fossati, Flavio Moroni, Alberto Chiarugi
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 2, Pp 269-279 (2009)
Histone deacetylase inhibitors (HDACi) are emerging tools for epigenetic modulation of gene expression and suppress the inflammatory response in models of systemic immune activation. Yet, their effects within the brain are still controversial. Also,
Externí odkaz:
https://doaj.org/article/5f65e428ed664f81bcd672e70498f06b
Autor:
Rolando Berlinguer-Palmini, Roberto Narducci, Kamyar Merhan, Arianna Dilaghi, Flavio Moroni, Alessio Masi, Tania Scartabelli, Elisa Landucci, Maria Sili, Antonio Schettini, Brian McGovern, Pleun Maskaant, Patrick Degenaar, Guido Mannaioni
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108689 (2014)
In the modern view of synaptic transmission, astrocytes are no longer confined to the role of merely supportive cells. Although they do not generate action potentials, they nonetheless exhibit electrical activity and can influence surrounding neurons
Externí odkaz:
https://doaj.org/article/02689ba7997e402f89982ef1ab3b7c61
Autor:
Rolando Berlinguer-Palmini, Alessio Masi, Roberto Narducci, Leonardo Cavone, Dario Maratea, Andrea Cozzi, Maria Sili, Flavio Moroni, Guido Mannaioni
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/a523649cea7345fb860e02b09e0d73fa
Autor:
Rolando Berlinguer-Palmini, Alessio Masi, Roberto Narducci, Leonardo Cavone, Dario Maratea, Andrea Cozzi, Maria Sili, Flavio Moroni, Guido Mannaioni
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e82180 (2013)
Limited information is available on the brain expression and role of GPR35, a Gi/o coupled receptor activated by kynurenic acid (KYNA). In mouse cultured astrocytes, we detected GPR35 transcript using RT-PCR and we found that KYNA (0.1 to 100 µM) de
Externí odkaz:
https://doaj.org/article/3254faf548974857b2055c2c9fe41d83
Autor:
Rolando Berlinguer Palmini, Elisabetta Gerace, Fabrizio Gardoni, Monica Di Luca, Flavio Moroni, Guido Mannaioni, Elisa Zianni, Tania Scartabelli, Domenico E. Pellegrini-Giampietro, Elisa Landucci, Daniela Iezzi
Publikováno v:
Journal of Neurochemistry. 155:638-649
We investigated the molecular events triggered by NMDA and 3,5-dihydroxyphenylglycine (DHPG) preconditioning, that lead to neuroprotection against excitotoxic insults (AMPA or oxygen and glucose deprivation) in rat organotypic hippocampal slices, wit
Autor:
Flavio Moroni
Publikováno v:
Brain and Heart Dynamics ISBN: 9783319903057
Brain and Heart Dynamics
Brain and Heart Dynamics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f2c15038332bc2858a05951db26f22
https://doi.org/10.1007/978-3-319-90305-7_53-1
https://doi.org/10.1007/978-3-319-90305-7_53-1
Autor:
Michela Lotti, Ilaria Pacileo, Elisa Bianchini, Giancarlo Fabbro, Riccardo Ciuti, Annibale Biggeri, Francesco Orsini, Assia Michahelles, Chiara Pracucci, Valentina Galli, Arianna Totti, Mariarita Quaranta, Lara Bertieri, Guido Mannaioni, Brunella Occupati, Emanuela Masini, Maria Sili, Cecilia Lanzi, Flavio Moroni, Arianna Dilaghi
Publikováno v:
European Addiction Research. 24:9-18
Aims: We aimed to improve the retention in treatment and therapeutic outcome of methadone maintenance treatment (MMT) patients by adjusting the oral methadone dose in order to reach a “target” plasma R-methadone level (80–250 ng/mL). Methods: A
Autor:
Nicola J. Curtin, Nathan A. Berger, Solomon H. Snyder, Raymond A. Swanson, Peter Radermacher, Csaba Szabó, Pal Pacher, Francisco Garcia Soriano, Robert S. B. Clark, Robert P. Strosznajder, Flavio Moroni, A. Hamid Boulares, Balazs Sumegi, Andrew L. Salzman, Valina L. Dawson, Salvatore Cuzzocrea, Alberto Chiarugi, Ted M. Dawson, Alexander Bürkle, Lucas Liaudet, György Haskó, Valérie C. Besson
Publikováno v:
British Journal of Pharmacology. 175:192-222
The recent clinical availability of the PARP inhibitor olaparib (Lynparza) opens the door for potential therapeutic repurposing for non-oncological indications. Considering (a) the preclinical efficacy data with PARP inhibitors in non-oncological dis