Unifying the spatial epidemiology and molecular evolution of emerging epidemics

Autor: Eric Delwart, Nimalan Arinaminpathy, Marc A. Suchard, Susan L. Stramer, Flavien Bernardin, Andrew Rambaut, Rebecca R. Gray, Oliver G. Pybus, Michael P. Busch, Philippe Lemey, Forrest W. Crawford

Publikováno v: Pybus, O G, Suchard, M A, Lemey, P, Bernardin, F J, Rambaut, A, Crawford, F W, Gray, R R, Arinaminpathy, N, Stramer, S L, Busch, M P & Delwart, E L 2012, ' Unifying the spatial epidemiology and molecular evolution of emerging epidemics ', Proceedings of the National Academy of Sciences, vol. 109, no. 37, pp. 15066-15071 . https://doi.org/10.1073/pnas.1206598109

We introduce a conceptual bridge between the previously unlinked fields of phylogenetics and mathematical spatial ecology, which enables the spatial parameters of an emerging epidemic to be directly estimated from sampled pathogen genome sequences. B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d059b03a40ed0e9d07a789837e1acbe
https://doi.org/10.1073/pnas.1206598109

Transfusion transmission of highly prevalent commensal human viruses

Autor: Flavien Bernardin, M.P. Busch, Eric Delwart, Eva Operskalski

Publikováno v: Transfusion. 50:2474-2483

BACKGROUND: Anellovirus species Torque teno virus (TTV), Torque teno mini virus (TTMV), and Torque teno midi virus (TTMDV) and flavivirus GBV-C are highly prevalent and genetically diverse chronic human viral infections that have not yet been associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be5df870e3fd5cff0f7172a6727f9ffb
https://doi.org/10.1111/j.1537-2995.2010.02699.x

Detection of HIV-1 in alternative specimen types using the APTIMA® HIV-1 RNA Qualitative Assay

Autor: M.P. Busch, Davey M. Smith, R. Hecht, Eric Delwart, Christopher D. Pilcher, Flavien Bernardin, Douglas D. Richman, Janel Dockter, Cristina Giachetti, C. Thomas Nugent

Publikováno v: Journal of Virological Methods. 159:10-14

Peripheral blood mononuclear cells (PBMCs), saliva, seminal plasma, and dried blood spots were evaluated as specimen types for the APTIMA HIV-1 RNA Qualitative Assay (APTIMA HIV-1 Assay), which employs a target capture step to recover HIV-1-specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f1fa932cbfde27ef79bcffc9c113aa
https://doi.org/10.1016/j.jviromet.2009.02.015

Human Immunodeficiency Virus Mutations during the First Month of Infection Are Preferentially Found in Known Cytotoxic T-Lymphocyte Epitopes

Autor: Eric Delwart, Denice Kong, Lee Ann Baxter-Lowe, Flavien Bernardin, Peddada Lorraine B

Publikováno v: Journal of Virology. 79:11523-11528

The full protein coding region of human immunodeficiency virus (HIV) genomes were sequenced using plasma collected from nine African-Americans prior to seroconversion and 7 to 28 days later. HIV mutations emerged in seven of these subjects at a genom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba92b03c3f9ede7a085c64a3a2b06b02
https://doi.org/10.1128/jvi.79.17.11523-11528.2005

Highly Uneven Distribution of Tenofovir-Selected Simian Immunodeficiency Virus in Different Anatomical Sites of Rhesus Macaques

Autor: Silvija I. Staprans, Eric Delwart, Flavien Bernardin, Magdalena Magierowska, Michael D. Miller, Koen K. A. Van Rompay, Seema Garg

Publikováno v: Journal of Virology. 78:2434-2444

Antiviral tenofovir monotherapy was used to determine whether drug-selected simian immunodeficiency virus (SIV) variants replaced their wild-type progenitors at the same rate in different tissues of six rhesus macaques. The relative frequencies of dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f3769b500c6d7ecda39450259d6659
https://doi.org/10.1128/jvi.78.5.2434-2444.2004