Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Flavia d'Alessio"'
Autor:
Alphonse Ouédraogo, Edith Christiane Bougouma, Nirianne Marie Q. Palacpac, Sophie Houard, Issa Nebie, Jean Sawadogo, Gloria D. Berges, Issiaka Soulama, Amidou Diarra, Denise Hien, Amidou Z. Ouedraogo, Amadou T. Konaté, Seni Kouanda, Akira Myoui, Sachiko Ezoe, Ken J. Ishii, Takanobu Sato, Flavia D’Alessio, Odile Leroy, Alfred B. Tiono, Simon Cousens, Toshihiro Horii, Sodiomon B. Sirima
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundBK-SE36/CpG is a recombinant blood-stage malaria vaccine candidate based on the N-terminal Plasmodium falciparum serine repeat antigen5 (SE36), adsorbed to aluminium hydroxide gel and reconstituted, prior to administration, with synthetic o
Externí odkaz:
https://doaj.org/article/e22bb3de30e5466fbb0802c8e128c365
Autor:
Issa Nebie, Nirianne Marie Q. Palacpac, Edith Christiane Bougouma, Amidou Diarra, Alphonse Ouédraogo, Flavia D’Alessio, Sophie Houard, Alfred B. Tiono, Simon Cousens, Toshihiro Horii, Sodiomon B. Sirima
Publikováno v:
Vaccines, Vol 12, Iss 2, p 166 (2024)
Information on the dynamics and decline/persistence of antibody titres is important in vaccine development. A recent vaccine trial in malaria-exposed, healthy African adults and children living in a malaria hyperendemic and seasonal area (Ouagadougou
Externí odkaz:
https://doaj.org/article/bcb2b2f1e57a46668334697fc2147ef5
Autor:
Alfred B. Tiono, Nirianne Marie Q. Palacpac, Edith Christiane Bougouma, Issa Nebie, Alphonse Ouédraogo, Sophie Houard, Nobuko Arisue, Flavia D’Alessio, Toshihiro Horii, Sodiomon B. Sirima
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundA vaccine targeting the erythrocyte stages of Plasmodium falciparum could play a role in preventing clinical disease. BK-SE36 is a promising malaria vaccine candidate that has shown a good safety profile and immunological responses during f
Externí odkaz:
https://doaj.org/article/b6ac4289b8df4d4194f456cf67156da0
Autor:
Nobuko Arisue, Nirianne Marie Q. Palacpac, Edward H. Ntege, Adoke Yeka, Betty Balikagala, Bernard N. Kanoi, Edith Christiane Bougouma, Alfred B. Tiono, Issa Nebie, Amidou Diarra, Sophie Houard, Flavia D’Alessio, Odile Leroy, Sodiomon B. Sirima, Thomas G. Egwang, Toshihiro Horii
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
BK-SE36, based on Plasmodium falciparum serine repeat antigen 5 (SERA5), is a blood-stage malaria vaccine candidate currently being evaluated in clinical trials. Phase 1 trials in Uganda and Burkina Faso have demonstrated promising safety and immunog
Externí odkaz:
https://doaj.org/article/6e1f6b310c064fc39df8180db3a65ff9
Autor:
Edith Christiane Bougouma, Nirianne Marie Q. Palacpac, Alfred B. Tiono, Issa Nebie, Alphonse Ouédraogo, Sophie Houard, Masanori Yagi, Sam Aboubacar Coulibaly, Amidou Diarra, Takahiro Tougan, Amidou Z. Ouedraogo, Issiaka Soulama, Nobuko Arisue, Jean Baptiste Yaro, Flavia D’Alessio, Odile Leroy, Simon Cousens, Toshihiro Horii, Sodiomon B. Sirima
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundA blood-stage vaccine targeting the erythrocytic-stages of the malaria parasite Plasmodium falciparum could play a role to protect against clinical disease. Antibodies against the P. falciparum serine repeat antigen 5 (SE47 and SE36 domains
Externí odkaz:
https://doaj.org/article/db77ababb24041078b2a6594464ac231
Autor:
Victorine A. Mensah, Sophie Roetynck, Ebrima K. Kanteh, Georgina Bowyer, Amy Ndaw, Francis Oko, Carly M. Bliss, Ya Jankey Jagne, Riccardo Cortese, Alfredo Nicosia, Rachel Roberts, Flavia D’Alessio, Odile Leroy, Babacar Faye, Beate Kampmann, Badara Cisse, Kalifa Bojang, Stephen Gerry, Nicola K. Viebig, Alison M. Lawrie, Ed Clarke, Egeruan B. Imoukhuede, Katie J. Ewer, Adrian V. S. Hill, Muhammed O. Afolabi
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
BackgroundHeterologous prime-boost vaccination with chimpanzee adenovirus 63 (ChAd63) and modified vaccinia virus Ankara (MVA) encoding multiple epitope string thrombospondin-related adhesion protein (ME-TRAP) has shown acceptable safety and promisin
Externí odkaz:
https://doaj.org/article/ec79be823a6948b69302a94bf68cd4c9
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 1, p e1003421 (2014)
Systemic iron homeostasis involves a negative feedback circuit in which the expression level of the peptide hormone hepcidin depends on and controls the iron blood levels. Hepcidin expression is regulated by the BMP6/SMAD and IL6/STAT signaling casca
Externí odkaz:
https://doaj.org/article/01d4fa0c77d1458d927b551e10bdb096
Autor:
Norbert Stockhofe, Edmond J. Remarque, Gerrit Koopman, Flavia D'Alessio, Sophie Houard, Othmar G. Engelhardt
Publikováno v:
Vaccine 36 (2018) 46
Vaccine, 36(46), 6895-6901
Vaccine, 36(46), 6895-6901
A major challenge in influenza research is the selection of an appropriate animal model that accurately reflects the disease and the protective immune response observed in humans. A workshop organised by the EDUFLUVAC consortium, a European Union fun
Autor:
Sophia Pavlova, Flavia D'Alessio, Edmond J. Remarque, Othmar G. Engelhardt, Norbert Stockhofe, Sophie Houard
Publikováno v:
Influenza and Other Respiratory Viruses
The development of broadly reactive influenza vaccines raises the need to identify the most appropriate immunoassays that can be used for the evaluation of so‐called universal influenza vaccines and to explore a path towards the standardisation of
Autor:
Benjamin Mordmüller, Odile Leroy, Stefan Jungbluth, Peter G. Kremsner, B. Kim Lee Sim, Nicola K. Viebig, Adrian V. S. Hill, Clemens H. M. Kocken, Flavia D'Alessio, Paul W. Bowyer, Alister Craig, Simon J. Draper, Chetan E. Chitnis, Adrian J. F. Luty
Publikováno v:
Vaccine. 33:6137-6144
The deployment of a safe and effective malaria vaccine will be an important tool for the control of malaria and the reduction in malaria deaths. With the launch of the 2030 Malaria Vaccine Technology Roadmap, the malaria community has updated the goa