Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Flavia S. A. Pelegrino"'
Publikováno v:
Experimental Eye Research. 94:150-156
Patients with tear dysfunction often experience increased irritation symptoms when subjected to drafty and/or low humidity environmental conditions. The purpose of this study was to investigate the effects of low humidity stress (LHS) on corneal barr
Autor:
Cintia S. de Paiva, Stephen C. Pflugfelder, Flavia S. A. Pelegrino, De-Quan Li, Fang Bian, Johanna Tukler Henriksson, Eugene A. Volpe
Publikováno v:
The ocular surface. 14(2)
Alkali burns to the cornea are among the most devastating injuries to the eye. The purpose of this study was to evaluate the effects of dexamethasone (Dex) or doxycycline (Doxy) on protease activity and corneal complications in a combined model (CM)
Autor:
Fang Bian, Eugene A. Volpe, Flavia L. Barbosa, Flavia S. A. Pelegrino, Cintia S. de Paiva, Rosa M. Corrales, Stephen C. Pflugfelder
Publikováno v:
Arthritis Research & Therapy
Introduction The lacrimal gland (LG) of the CD25-/- model of Sjögren’s syndrome (SS) has high interleukin (IL)-17, IL-13 and interferon-gamma (IFN-γ) cytokines. The specific contribution of these cytokines to the onset and severity of dacryoadeni
Autor:
Xiaobo Zhang, Niral B. Gandhi, Zhitao Su, Eugene A. Volpe, Flavia S. A. Pelegrino, Cintia S. de Paiva, Salman A. Rahman, De-Quan Li, Stephen C. Pflugfelder
Publikováno v:
Journal of leukocyte biology. 94(6)
TSP-1 is a physiologic activator of TGF-β, a critical induction factor for Th17-mediated immunity. The purpose of this study was to investigate the role of TSP-1 in the induction of the Th17 ocular surface response to DS. TSP-1KO and WT mice were su
Autor:
De-Quan Li, Michael E. Stern, William J. Farley, Andrew J. McClellan, Solherny B. Pangelinan, Jagdeep K. Raince, Flavia S. A. Pelegrino, Cintia S. de Paiva, John D. Pitcher, Stephen C. Pflugfelder, Ehsan Rahimy
Publikováno v:
Investigative ophthalmologyvisual science. 52(6)
The lacrimal gland (LG) is a dynamic organ that secretes proteins, electrolytes, and water to protect and support the ocular surface.1 The functional importance of the LG is reflected by its highly developed neural regulation. Stimulus of ocular surf
Autor:
Johanna Tukler-Henriksson, Cintia S. de Paiva, Achim H.-P. Krauss, Flavia S. A. Pelegrino, Rosa M. Corrales, Stephen C. Pflugfelder
Publikováno v:
Investigative Opthalmology & Visual Science. 56:5888
Dry eye disease (DED) is one of the most common and discomforting eye disorders. It has been defined as a multifactorial ocular surface disease more prevalent in women and the elderly. Dry eye disease is associated with symptoms of discomfort, visual
Autor:
Stephen C. Pflugfelder, Eugene A. Volpe, Cintia S. de Paiva, De-Quan Li, Fang Bian, Flavia S. A. Pelegrino
Publikováno v:
Investigative Opthalmology & Visual Science. 56:4908
Eye injuries in the military and civilian population are frequent events.1–4 The main causes of eye injuries in the military has changed with changes in strategy and weaponry. These include sharp, blast fragmentation, penetrating, and perforating i
Autor:
Stephen C. Pflugfelder, Niral B. Gandhi, Flavia S. A. Pelegrino, Cintia S. de Paiva, De-Quan Li, Eugene A. Volpe
Publikováno v:
Arthritis Research & Therapy
Introduction To investigate the role of interferon-gamma (IFN-γ) in the onset and severity of dacryoadenitis in the CD25 knockout (KO) mouse model of Sjögren Syndrome. Methods CD25/IFN-γ double KO (γDKO) mice were created by crossbreeding CD25KO