Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Flavia Regina Carreno"'
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e34844 (2012)
Vagal nerve stimulation (VNS) has been approved for treatment-resistant depression. Many antidepressants increase expression of brain-derived neurotrophic factor (BDNF) in brain or activate, via phosphorylation, its receptor, TrkB. There have been no
Externí odkaz:
https://doaj.org/article/f50463dc07194c4ab2b94b21da6ab292
Autor:
Flavia Regina Carreno
Publikováno v:
Biological psychiatry. 92(3)
Autor:
Alan Frazer, Vladislav Bugay, Robert Brenner, Flavia Regina Carreno, Alexandra Maxine McCoy, Daniel J. Lodge
Publikováno v:
Neuropsychopharmacology
Previous research has demonstrated that selective modulation of hippocampal transmission by systemic administration of an α5-GABA(A) receptor negative allosteric modulator, L-655,708, reproduces the sustained antidepressant-like (AD-like) effect of
Publikováno v:
International Journal of Neuropsychopharmacology
Background: Selective augmentation of hippocampal activity in ways similar to that caused by ketamine may have therapeutic advantages over ketamine, which has psychotomimetic and reinforcing effects likely due to effects outside the hippocampus (i.e.
Publikováno v:
Behav Brain Res
Numerous randomized double-blind clinical trials have consistently shown that that a single intravenous administration of a subanesthetic dose of ketamine to treatment-resistant depressed patients significantly improved depressive symptomatology rapi
Autor:
Alan Frazer, Flavia Regina Carreno
Major depressive disorder (MDD) is prevalent. Although standards antidepressants are more effective than placebo, up to 35% of patients do not respond to 4 or more conventional treatments and are considered to have treatment-resistant depression (TRD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3674f75854cb61af74ac2156a31c53c3
https://europepmc.org/articles/PMC5509631/
https://europepmc.org/articles/PMC5509631/
Publikováno v:
Clinical Psychopharmacology and Neuroscience
Treatment resistant depression (TRD) is a global health concern affecting a large proportion of depressed patients who then require novel therapeutic options. One such treatment option that has received some attention in the past several years is vag
Publikováno v:
Experimental Physiology. 98:922-933
Bile duct ligation (BDL) causes congestive liver failure that initiates hemodynamic changes including peripheral vasodilation and generalized edema. Peripheral vasodilation is hypothesized to then activate compensatory mechanisms including increased
A current hypothesis regarding the mechanism of antidepressant action suggests the involvement of brain derived neurotrophic factor (BDNF). Consistent with this hypothesis, the receptor for BDNF (and neurotrophin 4/5), Tropomyosin related kinase B (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aadaae07c15b04fb0754a5c4909cc6a
https://europepmc.org/articles/PMC4817548/
https://europepmc.org/articles/PMC4817548/