The Suitability of RNA from Positive SARS-CoV-2 Rapid Antigen Tests for Whole Virus Genome Sequencing and Variant Identification to Maintain Genomic Surveillance

Autor: Annamaria Cucina, Flavia Contino, Giuseppina Brunacci, Valentina Orlando, Mario La Rocca, Sergio Indelicato, Francesca Di Gaudio

Publikováno v: Diagnostics, Vol 13, Iss 24, p 3618 (2023)

The COVID-19 pandemic has transformed laboratory management, with a surge in demand for diagnostic tests prompting the adoption of new diagnostic assays and the spread of variant surveillance tools. Rapid antigen tests (RATs) were initially used only

Externí odkaz: https://doaj.org/article/926e451fe7a44103a82209c260786670

Granulocyte–colony stimulating factor plus plerixafor in patients with β-thalassemia major results in the effective mobilization of primitive CD34+ cells with specific gene expression profile

Autor: Elena Baiamonte, Rita Barone, Flavia Contino, Rosalia Di Stefano, Anna Marfia, Aldo Filosa, Emanuela D'Angelo, Salvatore Feo, Santina Acuto, Aurelio Maggio

Publikováno v: Thalassemia Reports, Vol 7, Iss 1 (2017)

Successful gene therapy for β-thalassemia requires optimal numbers of autologous gene-transduced hematopoietic stem and progenitor cells (HSPCs) with high repopulating capacity. Previous studies suggested superior mobilization in these patients by t

Externí odkaz: https://doaj.org/article/df256ac03d3c49c08c37b081b1b91404

Analysis of the Thymidylate Synthase Gene Structure in Colorectal Cancer Patients and Its Possible Relation with the 5-Fluorouracil Drug Response

Autor: A. Calascibetta, Flavia Contino, S. Feo, G. Gulotta, M. Cajozzo, A. Antona, G. Sanguedolce, R. Sanguedolce

Publikováno v: Journal of Nucleic Acids, Vol 2010 (2010)

Thymidylate synthase (TS) catalyzes methylation of dUMP to dTMP and it is the target for the 5-Fluorouracil (5-FU) activity. Barbour et al. showed that variant structural forms of TS in tumour cell lines confer resistance to fluoropyrimidines. We pla

Externí odkaz: https://doaj.org/article/2284fe57696243859265ca02b9fa81be

Changes in the Transcriptome Profiles of Human Amnion-Derived Mesenchymal Stromal/Stem Cells Induced by Three-Dimensional Culture: A Potential Priming Strategy to Improve Their Properties

Autor: Alessia Gallo, Nicola Cuscino, Flavia Contino, Matteo Bulati, Mariangela Pampalone, Giandomenico Amico, Giovanni Zito, Claudia Carcione, Claudio Centi, Alessandro Bertani, Pier Giulio Conaldi, Vitale Miceli

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 863, p 863 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 863

Mesenchymal stromal/stem cells (MSCs) are believed to function in vivo as a homeostatic tool that shows therapeutic properties for tissue repair/regeneration. Conventionally, these cells are expanded in two-dimensional (2D) cultures, and, in that cas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72f027743d654c7625750d0706f4904
http://hdl.handle.net/10447/555566

The Secreted Protein C10orf118 Is a New Regulator of Hyaluronan Synthesis Involved in Tumour-Stroma Cross-Talk

Autor: Arianna Parnigoni, Maria Luisa D'Angelo, Patrizia Cancemi, Flavia Contino, Evgenia Karousou, Paola Moretto, Elena Caravà, Davide Vigetti, Alberto Passi, Ilaria Caon, Manuela Viola, Barbara Bartolini, Nikos K. Karamanos

Publikováno v: Cancers, Vol 13, Iss 1105, p 1105 (2021)
Cancers
Volume 13
Issue 5

Simple Summary Hyaluronan is a main glycosaminoglycan in extracellular matrix with an important role in breast cancer progression. Alterations in its synthesis and size may affect tu-mour growth and metastasis. Communication between stromal and breas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0075667b2ed3743fee01730e397949
https://pubmed.ncbi.nlm.nih.gov/33807583