Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Flavia, Stefani"'
Autor:
Alexa J. Cleasby, Jessica Willan, Flavia Stefani, Helen E. Bryant, Cinzia Rinaldo, Philip G. Woodman, Barbara Ciani, Emma Grant, Alessandra Pisciottani, Neftali Flores-Rodriguez
Publikováno v:
Oncogenesis
Oncogenesis, Vol 8, Iss 5, Pp 1-14 (2019)
Willan, J, Cleasby, A J, Flores-Rodriguez, N, Stefani, F, Rinaldo, C, Pisciottani, A, Grant, E, Woodman, P, Bryant, H E & Ciani, B 2019, ' ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage ', Oncogenesis, vol. 8, no. 5, 29 . https://doi.org/10.1038/s41389-019-0136-0
Oncogenesis 8 (2019). doi:10.1038/s41389-019-0136-0
info:cnr-pdr/source/autori:Willan, Jessica; Cleasby, Alexa J.; Flores-Rodriguez, Neftali; Stefani, Flavia; Rinaldo, Cinzia; Pisciottani, Alessandra; Grant, Emma; Woodman, Philip; Bryant, Helen E.; Ciani, Barbara/titolo:ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage/doi:10.1038%2Fs41389-019-0136-0/rivista:Oncogenesis/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Oncogenesis, Vol 8, Iss 5, Pp 1-14 (2019)
Willan, J, Cleasby, A J, Flores-Rodriguez, N, Stefani, F, Rinaldo, C, Pisciottani, A, Grant, E, Woodman, P, Bryant, H E & Ciani, B 2019, ' ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage ', Oncogenesis, vol. 8, no. 5, 29 . https://doi.org/10.1038/s41389-019-0136-0
Oncogenesis 8 (2019). doi:10.1038/s41389-019-0136-0
info:cnr-pdr/source/autori:Willan, Jessica; Cleasby, Alexa J.; Flores-Rodriguez, Neftali; Stefani, Flavia; Rinaldo, Cinzia; Pisciottani, Alessandra; Grant, Emma; Woodman, Philip; Bryant, Helen E.; Ciani, Barbara/titolo:ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage/doi:10.1038%2Fs41389-019-0136-0/rivista:Oncogenesis/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Micronuclei represent the cellular attempt to compartmentalize DNA to maintain genomic integrity threatened by mitotic errors and genotoxic events. Some micronuclei show aberrant nuclear envelopes (NEs) that collapse, generating damaged DNA that can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f2f1099dfc47ad7ead86b431fa4564
https://eprints.whiterose.ac.uk/145075/1/Willan_et_al-2019-Oncogenesis.pdf
https://eprints.whiterose.ac.uk/145075/1/Willan_et_al-2019-Oncogenesis.pdf
Autor:
Alexa J. Cleasby, Emma Grant, Philip G. Woodman, Alessandra Pisciottani, Cinzia Rinaldo, Barbara Ciani, Willan J, Flavia Stefani, Helen E. Bryant, Neftali Flores-Rodriguez
1.AbstractMicronuclei represent the cellular attempt to compartmentalize DNA to maintain genomic integrity threatened by mitotic errors and genotoxic events. Micronuclei show aberrant nuclear envelopes that collapse, generating damaged DNA and promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63aa1d10f3b4ec960f14b379d6e0b56
https://doi.org/10.1101/476630
https://doi.org/10.1101/476630
The molecular basis for selective assembly of the UBAP1-containing endosome-specific ESCRT-I complex
Publikováno v:
Journal of Cell Science
ESCRT-I is essential for the multivesicular body (MVB) sorting of ubiquitylated cargo such as epidermal growth factor receptor, as well as for several cellular functions, such as cell division and retroviral budding. ESCRT-I has four subunits; TSG101
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a184c79bc3ef65f5a644b861b8871b13
http://europepmc.org/articles/PMC4007767
http://europepmc.org/articles/PMC4007767
Autor:
Deepankar, Gahloth, Colin, Levy, Graham, Heaven, Flavia, Stefani, Lydia, Wunderley, Paul, Mould, Matthew J, Cliff, Jordi, Bella, Alistair J, Fielding, Philip, Woodman, Lydia, Tabernero
Publikováno v:
Structure(London, England:1993)
Summary Endosomal sorting complexes required for transport (ESCRTs) are essential for ubiquitin-dependent degradation of mitogenic receptors, a process often compromised in cancer pathologies. Sorting of ubiquinated receptors via ESCRTs is controlled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69aa7d4d40734e66b5a7a8b63a17b2fb
https://pubmed.ncbi.nlm.nih.gov/27839950
https://pubmed.ncbi.nlm.nih.gov/27839950
Autor:
Stuart Pickering-Brown, Johanna Donovan, Janis Bennion, Aurelie Doyotte, Sandra Taylor, Kim Brownhill, Flavia Stefani, Ling Zhang, Philip G. Woodman, Sara Rollinson
Publikováno v:
Current Biology. 21:1245-1250
SummaryEndosomal sorting complexes required for transport (ESCRTs) regulate several events involving membrane invagination, including multivesicular body (MVB) biogenesis, viral budding, and cytokinesis [1]. In each case, upstream ESCRTs combine with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892a6976939cefcf1b5aa07c330f2cab
https://doi.org/10.1016/j.cub.2011.06.028
https://doi.org/10.1016/j.cub.2011.06.028
Autor:
Neftali, Flores-Rodriguez, David A, Kenwright, Pei-Hua, Chung, Andrew W, Harrison, Flavia, Stefani, Thomas A, Waigh, Victoria J, Allan, Philip G, Woodman
Publikováno v:
Journal of Cell Science
Endosomal sorting complexes required for transport (ESCRT)-0 sorts ubiquitylated EGFR within the early endosome so that the receptor can be incorporated into intralumenal vesicles. An important question is whether ESCRT-0 acts solely upon EGFR that h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e2ea05f7b5df22d96b6d374a46018c5
https://pubmed.ncbi.nlm.nih.gov/25588841
https://pubmed.ncbi.nlm.nih.gov/25588841