Therapy of human T-cell acute lymphoblastic leukaemia with a combination of anti-CD7 and anti-CD38-SAPORIN immunotoxins is significantly better than therapy with each individual immunotoxin.

Autor: Flavell, D J, Boehm, D A, Noss, A, Warnes, S L, Flavell, S U

Publikováno v: British Journal of Cancer. 2/15/2001, Vol. 84 Issue 4, p571. 8p.

Engineering a switchable toxin: the Potential Use of PDZ Domains in the Expression, Targeting and Activation of Modified Saporin Variants

Autor: Giansanti F., Di Leandro L., Koutris I., Pitari G., Fabbrini M. S., Lombardi A., Flavell D. J., Flavell, S. U., Gianni S., Ippoliti R.

Publikováno v: Protein engineering
23 (2010): 61–68.
info:cnr-pdr/source/autori:Giansanti F., Di Leandro L., Koutris I., Pitari G., Fabbrini M. S., Lombardi A., Flavell D. J., Flavell, S. U., Gianni S., Ippoliti R./titolo:Engineering a switchable toxin: the Potential Use of PDZ Domains in the Expression, Targeting and Activation of Modified Saporin Variants/doi:/rivista:Protein engineering (Print)/anno:2010/pagina_da:61/pagina_a:68/intervallo_pagine:61–68/volume:23

In this paper we describe an engineered form of the ribosome inactivating protein saporin (sapVSAV), bearing a C-terminal extra sequence that is recognized and bound by PDZ2 domain from the mouse PTP-BL protein. The co-expression of sapVSAV and PDZ2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::94d0c16dd95a36808f036409dc67efe2
https://publications.cnr.it/doc/11125

The potential use of PDZ domains in the expression, targeting and activation of modified saporin variants

Autor: Giansanti F., Di Leandro L., Pitari G., Koutris I., Fabbrini M. S., Lombardi A., Flavell D. J., Flavell S. U., Gianni S., Ippoliti R.

Publikováno v: 4th Fabish-Symposium for Cancer Research and Molecular Cell Biology; 2nd Targeted Tumor Therapies., Berlin, 2009
info:cnr-pdr/source/autori:Giansanti F., Di Leandro L., Pitari G., Koutris I., Fabbrini M. S., Lombardi A., Flavell D. J., Flavell S. U., Gianni S., Ippoliti R./congresso_nome:4th Fabish-Symposium for Cancer Research and Molecular Cell Biology; 2nd Targeted Tumor Therapies./congresso_luogo:Berlin/congresso_data:2009/anno:2009/pagina_da:/pagina_a:/intervallo_pagine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::a18be2996a31a8e944f713ab4d8cb7ac
https://publications.cnr.it/doc/102498

Comparison of the potency and therapeutic efficacy of the anti-CD7 immunotoxin HB2-saporin constructed with one or two saporin moieties per immunotoxin molecule.

Autor: Flavell, DJ, Boehm, DA, Noss, A, Flavell, SU, Flavell, D J, Boehm, D A, Flavell, S U

Publikováno v: British Journal of Cancer; Apr1997, Vol. 75 Issue 7, p1035-1043, 9p

High-dose mitoxantrone and etoposide conditioning in autologous bone marrow transplantation for relapsed Hodgkin's disease.

Autor: Lim, S.H., Baglin, T.P., Flavell, D. J., Flavell, S. U., Wimperis, J. Z., Marcus, R. E.

Publikováno v: European Journal of Haematology; Feb1992, Vol. 48 Issue 2, p110-114, 5p