Zobrazeno 1 - 10
of 9 959
pro vyhledávání: '"Flavell, A."'
Autor:
Haspel, Gal, Baker, Ben, Beets, Isabel, Boyden, Edward S, Brown, Jeffrey, Church, George, Cohen, Netta, Colon-Ramos, Daniel, Dyer, Eva, Fang-Yen, Christopher, Flavell, Steven, Goodman, Miriam B, Hart, Anne C, Izquierdo, Eduardo J, Kagias, Konstantinos, Lockery, Shawn, Lu, Yangning, Marblestone, Adam, Matelsky, Jordan, Mensh, Brett, Pereira, Talmo D, Pfister, Hanspeter, Rajan, Kanaka, Rotstein, Horacio G, Scholz, Monika, Shaevitz, Joshua W., Shlizerman, Eli, Simeon, Quilee, Skuhersky, Michael A, Tiruvadi, Vineet, Venkatachalam, Vivek, Wei, Donglai, Wester, Brock, Yang, Guangyu Robert, Yemini, Eviatar, Zimmer, Manuel, Kording, Konrad P
Just like electrical engineers understand how microprocessors execute programs in terms of how transistor currents are affected by their inputs, neuroscientists want to understand behavior production in terms of how neuronal outputs are affected by t
Externí odkaz:
http://arxiv.org/abs/2308.06578
Autor:
Robin Peter, Anil P. Bidkar, Kondapa Naidu Bobba, Luann Zerefa, Chandrashekhar Dasari, Niranjan Meher, Anju Wadhwa, Adam Oskowitz, Bin Liu, Brian W. Miller, Kai Vetter, Robert R. Flavell, Youngho Seo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Radiopharmaceutical therapy using $$\upalpha$$ α -emitting $$^{225}$$ 225 Ac is an emerging treatment for patients with advanced metastatic cancers. Measurement of the spatial dose distribution in organs and tumors is needed to inform treat
Externí odkaz:
https://doaj.org/article/e1d2c9d4e31443c086a6151ba318828e
Autor:
Meng-Han Wu, Felipe Valenca-Pereira, Francesca Cendali, Emily L. Giddings, Catherine Pham-Danis, Michael C. Yarnell, Amanda J. Novak, Tonya M. Brunetti, Scott B. Thompson, Jorge Henao-Mejia, Richard A. Flavell, Angelo D’Alessandro, M. Eric Kohler, Mercedes Rincon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Mitochondrial respiration is essential for the survival and function of T cells used in adoptive cellular therapies. However, strategies that specifically enhance mitochondrial respiration to promote T cell function remain limited. Here, we
Externí odkaz:
https://doaj.org/article/d0884f5a1b81480bad4290e7a5d667fa
Autor:
Xingxing Ren, Qiuyuan Liu, Peirong Zhou, Tingyue Zhou, Decai Wang, Qiao Mei, Richard A. Flavell, Zhanju Liu, Mingsong Li, Wen Pan, Shu Zhu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Epithelial barrier dysfunction and crypt destruction are hallmarks of inflammatory bowel disease (IBD). Intestinal stem cells (ISCs) residing in the crypts play a crucial role in the continuous self-renewal and rapid recovery of intestinal e
Externí odkaz:
https://doaj.org/article/e5a4e856daf14c8688835a13aa12fea9
Autor:
Frame, Emily A., Bobba, Kondapa N., Gunter, Donald L., Mihailescu, Lucian, Bidkar, Anil P., Flavell, Robert R., Vetter, Kai
Targeted alpha-particle therapy (TAT) has great promise as a cancer treatment. Arguably the most promising TAT radionuclide that has been proposed is $^{225}$Ac. The development of $^{225}$Ac-based radiopharmaceuticals has been hampered due to the la
Externí odkaz:
http://arxiv.org/abs/2212.07631
Autor:
Changhua Mu, Xiaoxi Liu, Andrew Riselli, James Slater, Evelyn Escobar, Duy Dang, Scott Drapeau, Romelyn Delos Santos, Stacy Andosca, Hao Nguyen, Peder E.Z. Larson, Robert Bok, Daniel B. Vigneron, John Kurhanewicz, David M. Wilson, Robert R. Flavell
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103091- (2024)
Summary: Tumor acidosis is one of the hallmarks indicating the initiation and progression of various cancers. Here, we present a protocol for preparing a hyperpolarized (HP) 13C-bicarbonate tissue pH MRI imaging contrast agent to detect aggressive tu
Externí odkaz:
https://doaj.org/article/26eee672a7554c34a6b37c0d4f69c4ee
Autor:
Tingting Geng, Duomeng Yang, Tao Lin, Andrew G. Harrison, Binsheng Wang, Ziming Cao, Blake Torrance, Zhichao Fan, Kepeng Wang, Yanlin Wang, Long Yang, Laura Haynes, Gong Cheng, Anthony T. Vella, Richard A. Flavell, Joao P. Pereira, Erol Fikrig, Penghua Wang
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105248- (2024)
Summary: Background: The ubiquitin regulatory X (UBX) domain-containing proteins (UBXNs) are putative adaptors for ubiquitin ligases and valosin-containing protein; however, their in vivo physiological functions remain poorly characterised. We recent
Externí odkaz:
https://doaj.org/article/d87759c87aec46d69a881a5096e264fd
Autor:
Alexandre M. Sorlin, Marina López-Álvarez, Jacob Biboy, Joe Gray, Sarah J. Rabbitt, Junaid Ur Rahim, Sang Hee Lee, Kondapa Naidu Bobba, Joseph Blecha, Mathew F.L. Parker, Robert R. Flavell, Joanne Engel, Michael Ohliger, Waldemar Vollmer, David M. Wilson
Publikováno v:
JACS Au, Vol 4, Iss 3, Pp 1039-1047 (2024)
Externí odkaz:
https://doaj.org/article/26fb8a542dcd4adc81aef174d5b3c7bf
Autor:
Cohen, Alexander E., Hastewell, Alasdair D., Pradhan, Sreeparna, Flavell, Steven W., Dunkel, Jorn
Spectral mode representations play an essential role in various areas of physics, from quantum mechanics to fluid turbulence, but they are not yet extensively used to characterize and describe the behavioral dynamics of living systems. Here, we show
Externí odkaz:
http://arxiv.org/abs/2205.10725
Autor:
Joshua Flavell, Peter John Nestor
Publikováno v:
PCN Reports, Vol 3, Iss 2, Pp n/a-n/a (2024)
Abstract The behavioral variant of frontotemporal dementia (bvFTD) is thought to be the commonest clinical presentation of frontotemporal lobar degeneration and is predominantly characterized by changes in behavior. In patients lacking unequivocal bi
Externí odkaz:
https://doaj.org/article/e6084efbecf64f81a84668b8629d33ab