Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Flak MB"'
Autor:
Tschurtschenthaler, M, Adolph, TE, Ashcroft, JW, Niederreiter, L, Bharti, R, Saveljeva, S, Bhattacharyya, J, Flak, MB, Shih, DQ, Fuhler, GM, Parkes, M, Kohno, K, Iwawaki, T, Janneke Van Der Woude, C, Harding, HP, Smith, AM, Peppelenbosch, MP, Targan, Ron, D, Rosenstiel, P, Blumberg, RS, Kaser, A
ATG16L1$^{T300A}$, a major risk polymorphism in Crohn's disease (CD), causes impaired autophagy, but it has remained unclear how this predisposes to CD. In this study, we report that mice with Atg16l1 deletion in intestinal epithelial cells (IECs) sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb5c91b087fef75dc2fad834f2c83bf0
Autor:
Matute JD; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; Division of Newborn Medicine, Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Duan J; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Flak MB; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Griebel P; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Tascon-Arcila JA; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Doms S; Guest Group Evolutionary Medicine, Max Planck Institute for Evolutionary Biology, Plön, Germany.; Institute of Experimental Medicine, Kiel University, Kiel, Germany., Hanley T; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Antanaviciute A; Medical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK., Gundrum J; The Forsyth Institute, Cambridge, MA., Mark Welch JL; Marine Biological Laboratory, Woods Hole, MA., Sit B; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA.; Department of Microbiology, Harvard Medical School, Boston, MA.; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA.; Howard Hughes Medical Institute, Boston, MA., Abtahi S; Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Fuhler GM; Department of Gastroenterology & Hepatology, Erasmus MC, University Medical Center, Rotterdam, Netherlands., Grootjans J; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology and Metabolism & Cancer Center Amsterdam, Amsterdam University Medical Centers, Amsterdam, Netherlands., Tran F; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Stengel ST; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., White JR; Resphera Biosciences, Baltimore, MD., Krupka N; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Haller D; Nutrition and Immunology, Technische Universität München, Freising, Germany., Clare S; Wellcome Trust Sanger Institute, Hinxton, UK., Lawley TD; Wellcome Trust Sanger Institute, Hinxton, UK., Kaser A; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, and Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Cambridge, UK., Simmons A; Medical Research Council (MRC) Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK., Glickman JN; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA., Bry L; Massachusetts Host-Microbiome Center, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Rosenstiel P; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Borisy G; The Forsyth Institute, Cambridge, MA., Waldor MK; Division of Infectious Diseases, Brigham and Women's Hospital, Boston, MA.; Department of Microbiology, Harvard Medical School, Boston, MA.; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA.; Howard Hughes Medical Institute, Boston, MA., Baines JF; Guest Group Evolutionary Medicine, Max Planck Institute for Evolutionary Biology, Plön, Germany.; Institute of Experimental Medicine, Kiel University, Kiel, Germany., Turner JR; Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Blumberg RS; Division of Gastroenterology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Publikováno v:
The Journal of experimental medicine [J Exp Med] 2023 Jan 02; Vol. 220 (1). Date of Electronic Publication: 2022 Nov 22.
Autor:
Flak MB; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, UK., Koenis DS; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ UK., Gonzalez-Nunez M; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ UK., Chopo-Pizarro A; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ UK., Dalli J; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ UK; Centre for Inflammation and Therapeutic Innovation, Queen Mary University of London, London, UK. Electronic address: j.dalli@qmul.ac.uk.
Publikováno v:
Biochemical pharmacology [Biochem Pharmacol] 2023 Jan; Vol. 207, pp. 115348. Date of Electronic Publication: 2022 Nov 15.
Publikováno v:
JCI insight [JCI Insight] 2022 Oct 24; Vol. 7 (20). Date of Electronic Publication: 2022 Oct 24.
Autor:
De Matteis R; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK., Flak MB; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Gonzalez-Nunez M; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK., Austin-Williams S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK., Palmas F; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK., Colas RA; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK., Dalli J; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK.; Centre for Inflammation and Therapeutic Innovation, Queen Mary University of London, London, UK.
Publikováno v:
Science advances [Sci Adv] 2022 Feb 04; Vol. 8 (5), pp. eabl5420. Date of Electronic Publication: 2022 Feb 02.
Autor:
Muñoz-Atienza E; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, London, UK., Flak MB; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, London, UK., Sirr J; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, London, UK., Paramonov NA; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, UK., Aduse-Opoku J; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, UK., Pitzalis C; Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and The London School of Medicine & Dentistry, London, UK., Curtis MA; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, UK.
Publikováno v:
Journal of dental research [J Dent Res] 2020 Apr; Vol. 99 (4), pp. 456-462. Date of Electronic Publication: 2020 Jan 06.
Autor:
Flak MB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, and., Koenis DS; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, and., Sobrino A; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, and., Smith J; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, and., Pistorius K; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, and., Palmas F; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, and., Dalli J; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, and.; Centre for Inflammation and Therapeutic Innovation, Queen Mary University of London, Charterhouse Square, London, United Kingdom.
Publikováno v:
The Journal of clinical investigation [J Clin Invest] 2020 Jan 02; Vol. 130 (1), pp. 359-373.
Autor:
Flak MB; Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Queen Mary University of London (QMUL), London, United Kingdom., Colas RA; Lipid Mediator Unit, William Harvey Research Institute, QMUL, London, United Kingdom., Muñoz-Atienza E; Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Queen Mary University of London (QMUL), London, United Kingdom., Curtis MA; Dental Institute, King's College London, London, United Kingdom., Dalli J; Lipid Mediator Unit, William Harvey Research Institute, QMUL, London, United Kingdom.; Centre for Inflammation and Therapeutic Innovation, QMUL, London, United Kingdom., Pitzalis C; Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute, Queen Mary University of London (QMUL), London, United Kingdom.; Centre for Inflammation and Therapeutic Innovation, QMUL, London, United Kingdom.
Publikováno v:
JCI insight [JCI Insight] 2019 Jul 11; Vol. 4 (13). Date of Electronic Publication: 2019 Jul 11 (Print Publication: 2019).
Autor:
Hosomi S; Department of Medicine, Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; Department of Gastroenterology, Osaka City University Graduate School of Medicine, Osaka, Japan., Grootjans J; Department of Medicine, Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands., Tschurtschenthaler M; Department of Medicine, Division of Gastroenterology, University of Cambridge, Cambridge, England, UK., Krupka N; Department of Medicine, Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Matute JD; Department of Medicine, Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.; Division of Newborn Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA., Flak MB; Department of Medicine, Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Martinez-Naves E; Department of Microbiology and Immunology, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain., Gomez Del Moral M; Department of Cell Biology, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain., Glickman JN; Gastrointestinal Pathology Division, Miraca Life Sciences, Newton, MA., Ohira M; Department of Gastroenterology, Osaka City University Graduate School of Medicine, Osaka, Japan., Lanier LL; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA.; Parker Institute for Cancer Immunotherapy, University of California, San Francisco, San Francisco, CA., Kaser A; Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands ak729@cam.ac.uk., Blumberg R; Department of Medicine, Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA rblumberg@partners.org.
Publikováno v:
The Journal of experimental medicine [J Exp Med] 2017 Oct 02; Vol. 214 (10), pp. 2985-2997. Date of Electronic Publication: 2017 Jul 26.
Autor:
Wright RD; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, United Kingdom., Souza PR; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, United Kingdom., Flak MB; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, United Kingdom., Thedchanamoorthy P; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, United Kingdom., Norling LV; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, United Kingdom., Cooper D; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, London, United Kingdom d.cooper@qmul.ac.uk.
Publikováno v:
Journal of leukocyte biology [J Leukoc Biol] 2017 Mar; Vol. 101 (3), pp. 717-726. Date of Electronic Publication: 2016 Oct 12.