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Scaffold stabilization of a G-triplex and study of its interactions with G-quadruplex targeting ligands

Autor: Vignon, Anthony, Flaget, Arthur, Michelas, Maxime, Djeghdir, Mehdi, Coche-Guerente, Liliane, Decottignies, Anabelle, Moreno-Betancourt, Angélica, Berthet, Nathalie, Devaux, Alexandre, Perenon, M., Weynand, Justin, Bonnet, Hughes, Loiseau, Frédérique, Ravanat, Jean-Luc, Gillard, Martin, Laramée-Milette, Baptiste, Deraedt, Quentin, Hanan, Garry, Loiseau, Fredérique, Elias, Benjamin, Marcélis, Lionel, MacDonald, Hannah, Bonnet, Hugues, Van der Heyden, Angéline, Spinelli, Nicolas, Coche-Guérente, Liliane, Bonnat, Laureen, Dautriche, Maelle, Saidi, Taous, Revol-Cavalier, Johana, Dejeu, Jérôme, Defrancq, Eric, LAVERGNE, Thomas

Publikováno v: Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2019, 17 (38), pp.8726-8736. ⟨10.1039/c9ob01537j⟩

International audience; G-triplex nucleic acid structures (G3) have been conjectured to form in vivo but little is known about their physiological functions. The identification of ligands capable of specific binding to G3 structures is therefore high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677ba9e86be09d678ce8f9c8488527b7
https://hal.univ-grenoble-alpes.fr/hal-02944843