Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Flávio A. Violante"'
Publikováno v:
Rapid Communications in Mass Spectrometry. 25:423-428
Using electrospray ionization (tandem) mass spectrometry (ESI-MS(/MS)) spectrometric experiments, the Sandmeyer reaction was monitored on-line, and key intermediates were intercepted and characterized for the first time. The mechanistic information p
Autor:
Simon J. Garden, Flávio A. Violante, Michelle J. C. Rezende, Rosangela B. da Silva, Bárbara V. Silva, Angelo C. Pinto, Jose C. Torres
Publikováno v:
Química Nova. 31:924-929
Convolutamydine A is a member of a family of oxindole alkaloids isolated from the Floridian marine bryozan Amathia convoluta in 8.6x10-6 % yield. This compound is interesting as it has been described in the literature to have significant pharmacologi
Autor:
Núbia Moura Ribeiro, Angelo C. Pinto, Marluce Oliveira Dias, Bárbara V. Silva, Flávio A. Violante
Publikováno v:
Catalysis Communications. 8:2130-2136
A fast and efficient solvent-free procedure to prepare isatin ketals has been developed. Three different clays, commercial Montmorillonite K10 (Aldrich Co.) and two natural clays, were used as catalysts. A Brazilian-manufactured microwave oven was us
Autor:
Rodrigo J. Corrêa, Angelo C. Pinto, Gianluigi Luppi, Magda Monari, Quirinus B. Broxterman, Bernard Kaptein, Simon J. Garden, Flávio A. Violante, Claudia Tomasini
Publikováno v:
Tetrahedron. 62:12017-12024
The first total synthesis of (R)-convolutamydine A has been achieved by the organocatalytic addition of acetone to 4,6-dibromoisatin. The absolute configuration was determined by single crystal X-ray diffraction. DFT studies were used to model the tr
Autor:
Simon J. Garden, Jose C. Torres, Angelo C. Pinto, Flávio A. Violante, Maria D. Vargas, Ronaldo A. Pilli
Publikováno v:
Tetrahedron. 58:4487-4492
The Sonogashira–Heck–Cassar reaction of ferrocenylacetylene with aryl- and heteroaryl halides was shown to be a facile and convenient route for the synthesis of 1-ferrocenyl-2-aryl- and 1-ferrocenyl-2-heteroarylacetylenes in high yields. Addition
Autor:
Patricia Dias Fernandes, Renata S. Zardo, Angelo C. Pinto, Flávio A. Violante, Gabriela S.M. Figueiredo, Bárbara V. Silva
Publikováno v:
Pharmacology, biochemistry, and behavior. 103(3)
Convolutamydine A, an oxindole that originated from a marine bryozoan, has several biological effects. In this study, we aimed to investigate the antinociceptive effects of convolutamydine A and two new synthetic analogues.Convolutamydine A and the t
Publikováno v:
Rapid communications in mass spectrometry : RCM. 25(3)
Using electrospray ionization (tandem) mass spectrometry (ESI-MS(/MS)) spectrometric experiments, the Sandmeyer reaction was monitored on-line, and key intermediates were intercepted and characterized for the first time. The mechanistic information p
Autor:
Simon J. Garden, Angelo C. Pinto, Flávio A. Violante, Jose C. Torres, Ronaldo A. Pilli, Maria D. Vargas
Publikováno v:
ChemInform. 33
The Sonogashira–Heck–Cassar reaction of ferrocenylacetylene with aryl- and heteroaryl halides was shown to be a facile and convenient route for the synthesis of 1-ferrocenyl-2-aryl- and 1-ferrocenyl-2-heteroarylacetylenes in high yields. Addition
Autor:
Gianluigi Luppi, Simon J. Garden, Rodrigo J. Corrêa, Quirinus B. Broxterman, Angelo C. Pinto, Bernard Kaptein, Magda Monari, Claudia Tomasini, Flávio A. Violante
Publikováno v:
ChemInform. 38
The first total synthesis of (R)-convolutamydine A has been achieved by the organocatalytic addition of acetone to 4,6-dibromoisatin. The absolute configuration was determined by single crystal X-ray diffraction. DFT studies were used to model the tr
Isatins inhibit cyclooxygenase-2 and inducible nitric oxide synthase in a mouse macrophage cell line
Autor:
Maria Eline Matheus, Flávio A. Violante, Patricia Dias Fernandes, Angelo C. Pinto, Simon J. Garden
Publikováno v:
European journal of pharmacology. 556(1-3)
Isatin is a versatile compound with a diversity of effects. We designed to investigate the inhibitory effect of isatin derivatives on lipopolysaccharide/interferon-gamma-induced expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-