Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Flávio A. F. M. Bezerra"'
Autor:
Marcelle L. F. Bispo, Camilo H. S. Lima, Laura N. F. Cardoso, André L. P. Candéa, Flávio A. F. M. Bezerra, Maria C. S. Lourenço, Maria G. M. O. Henriques, Ricardo B. Alencastro, Carlos R. Kaiser, Marcus V. N. Souza, Magaly G. Albuquerque
Publikováno v:
Pharmaceuticals, Vol 10, Iss 2, p 52 (2017)
In an ongoing research program for the development of new anti-tuberculosis drugs, we synthesized three series (A, B, and C) of 7-chloro-4-aminoquinolines, which were evaluated in vitro against Mycobacterium tuberculosis (MTB). Now, we report the ant
Externí odkaz:
https://doaj.org/article/1bd0b3f01c1141e3a7d926e13ac67d2d
Autor:
Rodrigo Pedro Soares, Flávio A. F. M. Bezerra, Marcelle de Lima Ferreira Bispo, Marcus V. N. de Souza, Caryne Margotto Bertollo, Laura N. F. Cardoso, Maria C.S. Lourenço
Publikováno v:
Mediterranean Journal of Chemistry, Vol 4, Iss 1, Pp 1-8 (2015)
A series of eight 7-chloro-4-alkoxyquinoline derivatives (2a-h) have been synthesized and their in vitro (antimycobacterial) activity against Mycobacterium tuberculosis was evaluated. Furthermore, all the active compounds were selected for evaluation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5694a22974f1a9e32d64991f130b9ed4
https://doi.org/10.13171/mjc.4.1.2015.19.02.10.18/desouza
https://doi.org/10.13171/mjc.4.1.2015.19.02.10.18/desouza
Autor:
Flávio A. F. M. Bezerra, James L. Wardell, Carlos R. Kaiser, Marcelle de Lima Ferreira Bispo, Solange M. S. V. Wardell, Laura N. F. Cardoso, Marcele Neves Rocha, Rodrigo Pedro Soares, Marcus V. N. de Souza, Maria C.S. Lourenço
Publikováno v:
Archiv der Pharmazie. 347:432-448
A series of N-acylhydrazonyl-thienyl derivatives (compounds 2 and 3), mainly of the type 2-(aryl-CH=N-NHCOCH2 )-thiene (2: aryl = substituted-phenyl; 3: aryl = heteroaryl) were evaluated against Mycobacterium tuberculosis. Particularly active compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eca6edbade29a00a0f63ce11a4590868
https://doi.org/10.1002/ardp.201300417
https://doi.org/10.1002/ardp.201300417
Autor:
Fernando de C. da Silva, Nubia Boechat, Maria C.S. Lourenço, Priscila R. C. Martins, Gerson P. da Silva, Antoniana U. Krettli, Nathalia V da Silva, Mônica M. Bastos, Brunno M Teixeira, Flávio A. F. M. Bezerra, Maria de Lourdes G. Ferreira, Carolina C. P. Costa, Angelo C. Pinto, Anna Caroline Campos Aguiar, Sabrina B. Ferreira, Vitor F. Ferreira, Marilia S. Costa, Ane Louise S Camilo
Publikováno v:
Journal of Medicinal Chemistry. 54:5988-5999
The purpose of this study was to prepare various 4-substituted N-phenyl-1,2,3-triazole derivatives using click chemistry. The derivatives were screened in vitro for antimicrobial activity against Mycobacterium tuberculosis strain H37Rv (ATCC 27294) u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7714dddfa9eccdabd620753be2fa8d4c
https://doi.org/10.1021/jm2003624
https://doi.org/10.1021/jm2003624
Autor:
Flávio A. F. M. Bezerra, André L. P. Candéa, Carlos R. Kaiser, M. C. S. Lourenco, Marcelle de Lima Ferreira, Camilo Henrique da Silva Lima, Maria das Graças M. O. Henriques, M. V. N. de Souza
Publikováno v:
Medicinal Chemistry. 7:245-249
A series of nine N'-(E)-heteroaromatic-pyrazine-2-carbohydrazide derivatives (5a-f and 6a-c) have been synthesized and evaluated against M. tuberculosis ATCC 27294 using the micro plate Alamar Blue assay (MABA), being the activities expressed as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f281d7823a6374d1c11dc0df6680b683
https://doi.org/10.2174/157340611795564303
https://doi.org/10.2174/157340611795564303
Autor:
Flávio A. F. M. Bezerra, Maria C.S. Lourenço, Ana Paula Soares Fontes, Mauro V. de Almeida, Lígia Maria Mendonça Vieira
Publikováno v:
European Journal of Medicinal Chemistry. 44:4107-4111
The fluoroquinolones are an important family of synthetic antimicrobial agents being clinically used over the past thirty years. In addition, some fluoroquinolones have been used in the development of anticancer drugs, and others have demonstrated an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266da320586580f728b12a79b7514886
https://doi.org/10.1016/j.ejmech.2009.05.001
https://doi.org/10.1016/j.ejmech.2009.05.001
Autor:
Carlos R. Kaiser, Flávio A. F. M. Bezerra, Camilo Henrique da Silva Lima, Laura N. F. Cardoso, Magaly Girão Albuquerque, André L. P. Candéa, Marcelle de Lima Ferreira Bispo, Marcus V. N. de Souza, Maria C.S. Lourenço, Ricardo Bicca de Alencastro, Maria das Graças M. O. Henriques
Publikováno v:
Pharmaceuticals; Volume 10; Issue 2; Pages: 52
Pharmaceuticals, Vol 10, Iss 2, p 52 (2017)
Pharmaceuticals
Pharmaceuticals, Vol 10, Iss 2, p 52 (2017)
Pharmaceuticals
In an ongoing research program for the development of new anti-tuberculosis drugs, we synthesized three series (A, B, and C) of 7-chloro-4-aminoquinolines, which were evaluated in vitro against Mycobacterium tuberculosis (MTB). Now, we report the ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074377a1b978bd73a7195676206c1004
https://doi.org/10.3390/ph10020052
https://doi.org/10.3390/ph10020052
Autor:
Carlos R. Kaiser, Laura N. F. Cardoso, Flávio A. F. M. Bezerra, André L. P. Candéa, Karla C. Pais, Maria C.S. Lourenço, Marcus V. N. de Souza, Maria das Graças M. O. Henriques, Marcelle de Lima Ferreira
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:6272-6274
A series of twenty-one 7-chloro-4-quinolinylhydrazones (3a-u) have been synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H(37)Rv. The compounds 3f, 3i and 3o were non-cytotoxic and exhibited an im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a71511c8f7161b72dcc037203292fc0
https://doi.org/10.1016/j.bmcl.2009.09.098
https://doi.org/10.1016/j.bmcl.2009.09.098
Autor:
Laura N F, Cardoso, Marcelle L F, Bispo, Carlos R, Kaiser, James L, Wardell, Solange M S V, Wardell, Maria C S, Lourenço, Flávio A F M, Bezerra, Rodrigo P P, Soares, Marcele N, Rocha, Marcus V N, de Souza
Publikováno v:
Archiv der Pharmazie. 347(6)
A series of N-acylhydrazonyl-thienyl derivatives (compounds 2 and 3), mainly of the type 2-(aryl-CH=N-NHCOCH2 )-thiene (2: aryl = substituted-phenyl; 3: aryl = heteroaryl) were evaluated against Mycobacterium tuberculosis. Particularly active compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::959c9ef32e779220098054e791e7483d
https://pubmed.ncbi.nlm.nih.gov/24616002
https://pubmed.ncbi.nlm.nih.gov/24616002
Autor:
Sabrina Baptista Ferreira, Fernando de C. da Silva, Vitor F. Ferreira, Carlos R. Kaiser, Angelo C. Pinto, Maria C.S. Lourenço, Flávio A. F. M. Bezerra
Publikováno v:
ChemInform. 41
A series of alpha- and beta-pyran naphthoquinones (lapachones) have been synthesized and evaluated for their in-vitro antibacterial activity against Mycobacterium tuberculosis strain H37Rv (ATCC 27294) using the Alamar-Blue susceptibility test; the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff1916b87ed55a81270f6c51e3d633c
https://doi.org/10.1002/chin.201025117
https://doi.org/10.1002/chin.201025117