Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Flávia V. Soares"'
Autor:
Alexandre A. de Castro, Letícia C. Assis, Flávia V. Soares, Kamil Kuca, Daniel A. Polisel, Elaine F. F. da Cunha, Teodorico C. Ramalho
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 436 (2020)
Acetylcholinesterase (AChE) is the key enzyme responsible for deactivating the ACh neurotransmitter. Irreversible or prolonged inhibition of AChE, therefore, elevates synaptic ACh leading to serious central and peripheral adverse effects which fall u
Externí odkaz:
https://doaj.org/article/2dbcb7dbc70f41d5af3574e6d784cf2d
Autor:
Flávia V. Soares, Alexandre A. de Castro, Ander F. Pereira, Daniel H. S. Leal, Daiana T. Mancini, Ondrej Krejcar, Teodorico C. Ramalho, Elaine F. F. da Cunha, Kamil Kuca
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 4, p 1257 (2018)
Organophosphorus compounds (OP) are part of a group of compounds that may be hazardous to health. They are called neurotoxic agents because of their action on the nervous system, inhibiting the acetylcholinesterase (AChE) enzyme and resulting in a ch
Externí odkaz:
https://doaj.org/article/8c7ab4eedaff41cc8b66b315ef36ad0b
Autor:
Teodorico C. Ramalho, Kamil Kuca, Daniel A. Polisel, Daniel H. S. Leal, Elaine F. F. da Cunha, Ander Francisco Pereira, Alexandre A. de Castro, Eugenie Nepovimova, Melissa S. Caetano, Flávia V. Soares
Publikováno v:
Expert Review of Neurotherapeutics. 19:375-395
Alzheimer's disease (AD) is the most common cause of dementia. Clinical progress in this pathogenesis field has drawn the attention of researchers, stimulating the investigation of novel treatment methods. Current therapies that deal with cholinester
Autor:
Elaine F. F. da Cunha, Daiana T. Mancini, Teodorico C. Ramalho, Alexandre A. de Castro, Melissa S. Caetano, Flávia V. Soares, Daniela Rodrigues Silva, Ander Francisco Pereira, Telles Cardoso Silva
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 37:2154-2164
Organophosphorus compounds (OP) nerve agents are among the most toxic chemical substances known. Their toxicity is due to their ability to bind to acetylcholinesterase. Currently, some enzymes, such as phosphotriesterase, human serum paraoxonase 1 an
Autor:
Daniel A. Polisel, Flávia V. Soares, Teodorico C. Ramalho, Elaine F. F. da Cunha, Letícia C. Assis, Alexandre A. de Castro, Kamil Kuca
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 436 (2020)
Biomolecules
Biomolecules
Acetylcholinesterase (AChE) is the key enzyme responsible for deactivating the ACh neurotransmitter. Irreversible or prolonged inhibition of AChE, therefore, elevates synaptic ACh leading to serious central and peripheral adverse effects which fall u
Autor:
Daniel H. S. Leal, Flávia V. Soares, Elaine F. F. da Cunha, Teodorico C. Ramalho, Kamil Kuca, Ander Francisco Pereira, Alexandre A. de Castro
Publikováno v:
Current Alzheimer Research. 15:1161-1178
Introduction: Alzheimer's disease is known to be a chronic disease, with an estimated prevalence of about 10-30%, considering the population over 60 years of age. Most patients with this disorder (> 95%) present the sporadic form, being characterized
Autor:
Alexandre A. de Castro, Jéssika Poliana Teixeira, Teodorico C. Ramalho, Elaine F. F. da Cunha, Flávia V. Soares
Publikováno v:
Molecules
Alzheimer’s disease (AD) is a neurodegenerative disease that is usually accompanied by aging, increasingly being the most common cause of dementia in the elderly. This disorder is characterized by the accumulation of beta amyloid plaques (Aβ) resu
Autor:
Flávia V. Soares, Ander Francisco Pereira, Elaine F. F. da Cunha, Daniel H. S. Leal, Daiana T. Mancini, Alexandre A. de Castro, Teodorico C. Ramalho
Publikováno v:
Chemico-biological interactions. 308
Organophosphorus compounds have been widely employed to the development of warfare nerve agents and pesticides, resulting in a huge number of people intoxicated annually, being a serious problem of public health. Efforts worldwide have been done in o