Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Flávia Pires Maximiano"'
Autor:
Flávia Pires Maximiano, Guilherme Hideki Yoshizane Costa, Jacqueline de Souza, Marcílio Sérgio Soares da Cunha-Filho
Publikováno v:
Química Nova, Vol 33, Iss 8, Pp 1714-1719 (2010)
Currently, benznidazole (BNZ) is a unique therapeutic alternative available in Brazil to treat Chagas disease. Despite its traditional medical use, little is known about the chemical nature of this drug. A detailed study of the physicochemical proper
Externí odkaz:
https://doaj.org/article/f9373f8611ec434a9b410f910dcc165d
Autor:
Kátia Monteiro Novack, Felipe Sanches Garcia, Marcilio Cunha-Filho, Flávia Pires Maximiano, Livia L. Sa-Barreto, Pricila Castilho Gustmann
Publikováno v:
Pharmaceutical Development and Technology. 18:1035-1041
Benznidazole (BNZ) is the primary chemotherapeutic agent for treating Chagas' disease; however, its poor water solubility and irregular oral absorption lead to the treatment failure in the chronic phase. The aim of this work was to investigate the ut
Autor:
Flávia Pires Maximiano, Marcilio Cunha-Filho, Maria Terezinha Bahia, Kátia Monteiro Novack, Lívia Lira de Sá-Barreto
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 106:819-824
The purpose of this study was to investigate the polymorphism and compatibility of benznidazole (BNZ), a drug used in the treatment of Chagas disease. This drug was subjected to a polymorphic screen using a number of solvents and precipitation proced
Autor:
Guilherme Hideki Yoshizane Costa, Lívia Cristina Lira de Sá Barreto, Marcilio Cunha-Filho, Maria Terezinha Bahia, Flávia Pires Maximiano
Publikováno v:
The Journal of pharmacy and pharmacology. 63(6)
Objectives Benznidazole (BNZ), the primary chemotherapy agent used to treat Chagas disease, has poor aqueous solubility, which results in low bioavailability. The purpose of this work was to develop stable effervescent tablets using an inclusion comp
Autor:
Isabel Mayer de Andrade, Marcilio Cunha-Filho, Maria Terezinha Bahia, Vivian Paulino Figueiredo, Lívia Cristina Lira de Sá-Barreto, André Talvani, Lívia Maria de Paula, Flávia Pires Maximiano
Publikováno v:
Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
Benznidazole (BNZ) is traditionally used to treat Chagas disease. Despite its common use, BNZ has a poor water solubility and a variable bioavailability. The purpose of this study was to prepare BNZ microcrystals by solvent change precipitation and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd63a0d0789d4dba80bdf6bdefea69e
http://www.repositorio.ufop.br/handle/123456789/4418
http://www.repositorio.ufop.br/handle/123456789/4418
Autor:
Marcilio Cunha-Filho, Jacqueline de Souza, Flávia Pires Maximiano, Guilherme Hideki Yoshizane Costa
Publikováno v:
Química Nova, Volume: 33, Issue: 8, Pages: 1714-1719, Published: 2010
Química Nova v.33 n.8 2010
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova v.33 n.8 2010
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Currently, benznidazole (BNZ) is a unique therapeutic alternative available in Brazil to treat Chagas disease. Despite its traditional medical use, little is known about the chemical nature of this drug. A detailed study of the physicochemical proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f15c2c0b09eb3be76047a4c9c107d9
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000800018&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000800018&lng=en&tlng=en