Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Flávia Melo Cunha de Pinho Pessoa"'
Autor:
Flávia Melo Cunha de Pinho Pessoa, Marcelo Braga de Oliveira, Igor Valentim Barreto, Anna Karolyna da Costa Machado, Deivide Sousa de Oliveira, Rodrigo Monteiro Ribeiro, Jaira Costa Medeiros, Aurélia da Rocha Maciel, Fabiana Aguiar Carneiro Silva, Lívia Andrade Gurgel, Kaira Mara Cordeiro de Albuquerque, Germison Silva Lopes, Ricardo Parente Garcia Vieira, Jussara Alencar Arraes, Meton Soares de Alencar Filho, André Salim Khayat, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho, Caroline Aquino Moreira-Nunes
Publikováno v:
DNA, Vol 4, Iss 3, Pp 285-299 (2024)
The detection of genetic alterations in patients with acute leukemias is essential for the targeting of more specific and effective therapies. Therefore, the aim of this study was to compare the sensitivity of Nested-PCR and RT-qPCR techniques in the
Externí odkaz:
https://doaj.org/article/8a444e94819c4c8980b552446fa53025
Autor:
Renan Brito Gadelha, Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Laudreísa da Costa Pantoja, Igor Valentim Barreto, Rodrigo Monteiro Ribeiro, Manoel Odorico de Moraes Filho, Maria Elisabete Amaral de Moraes, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 11, Pp 5498-5515 (2022)
The WD repeat containing antisense to TP53 (WRAP53) gene codifies an antisense transcript for tumor protein p53 (TP53), stabilization (WRAP53α), and a functional protein (WRAP53β, WDR79, or TCAB1). The WRAP53β protein functions as a scaffolding pr
Externí odkaz:
https://doaj.org/article/f98d24812b224b63af1ba3f66354a15f
Autor:
Igor Valentim Barreto, Flávia Melo Cunha de Pinho Pessoa, Caio Bezerra Machado, Laudreísa da Costa Pantoja, Rodrigo Monteiro Ribeiro, Germison Silva Lopes, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho, Lucas Eduardo Botelho de Souza, Rommel Mário Rodriguez Burbano, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Hematopoietic stem cells (HSCs) are known for their ability to proliferate and self-renew, thus being responsible for sustaining the hematopoietic system and residing in the bone marrow (BM). Leukemic stem cells (LSCs) are recognized by their stemnes
Externí odkaz:
https://doaj.org/article/d1b11a17fb2d438fbf02e483915c65cb
Autor:
Flávia Melo Cunha de Pinho Pessoa, Caio Bezerra Machado, Igor Valentim Barreto, Giulia Freire Sampaio, Deivide de Sousa Oliveira, Rodrigo Monteiro Ribeiro, Germison Silva Lopes, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho, Lucas Eduardo Botelho de Souza, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1098 (2023)
Acute myeloid leukemia (AML) is a hematologic malignancy that occurs due to alterations such as genetic mutations, chromosomal translocations, or changes in molecular levels. These alterations can accumulate in stem cells and hematopoietic progenitor
Externí odkaz:
https://doaj.org/article/69ec0988da82411ab1eb3f706fb99da4
Autor:
Igor Valentim Barreto, Caio Bezerra Machado, Davi Benevides Almeida, Flávia Melo Cunha de Pinho Pessoa, Renan Brito Gadelha, Laudreísa da Costa Pantoja, Deivide de Sousa Oliveira, Rodrigo Monteiro Ribeiro, Germison Silva Lopes, Manoel Odorico de Moraes Filho, Maria Elisabete Amaral de Moraes, André Salim Khayat, Edivaldo Herculano Correa de Oliveira, Caroline Aquino Moreira-Nunes
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1784 (2022)
Multiple myeloma (MM) is a blood cell neoplasm characterized by excessive production of malignant monoclonal plasma cells (activated B lymphocytes) by the bone marrow, which end up synthesizing antibodies or antibody fragments, called M proteins, in
Externí odkaz:
https://doaj.org/article/a04c7cd0ccad49269e6904960a555f1b
Autor:
Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Emerson Lucena da Silva, Laudreísa da Costa Pantoja, Rodrigo Monteiro Ribeiro, Manoel Odorico de Moraes Filho, Maria Elisabete Amaral de Moraes, Raquel Carvalho Montenegro, Rommel Mário Rodriguez Burbano, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1604 (2021)
Cancer is still a major barrier to life expectancy increase worldwide, and hematologic neoplasms represent a relevant percentage of cancer incidence rates. Tumor dependence of continuous proliferative signals mediated through protein kinases overexpr
Externí odkaz:
https://doaj.org/article/02c9551f195f4cee92efdae133b64a29
Autor:
Flávia Melo Cunha de Pinho Pessoa, Caio Bezerra Machado, Emerson Lucena da Silva, Laudreísa da Costa Pantoja, Rodrigo Monteiro Ribeiro, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes Filho, Raquel Carvalho Montenegro, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
International journal of molecular sciences. 23(7)
The increasing numbers of cancer cases worldwide and the exceedingly high mortality rates of some tumor subtypes raise the question about if the current protocols for cancer management are effective and what has been done to improve upon oncologic pa
Autor:
Ana Beatriz Aguiar Sanford, Leidivan Sousa da Cunha, Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Abigail Nayara dos Santos Silva, Rodrigo Monteiro Ribeiro, Fabiano Cordeiro Moreira, Manoel Odorico de Moraes Filho, Maria Elisabete Amaral de Moraes, Lucas Eduardo Botelho de Souza, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
International Journal of Molecular Sciences. 23:8212
The circadian clock (CC) is a daily system that regulates the oscillations of physiological processes and can respond to the external environment in order to maintain internal homeostasis. For the functioning of the CC, the clock genes (CG) act in di
Autor:
Manoel Odorico de Moraes Filho, Caio Bezerra Machado, Laudreísa da Costa Pantoja, Emerson Lucena da Silva, Rodrigo Monteiro Ribeiro, Caroline Aquino Moreira-Nunes, Flávia Melo Cunha de Pinho Pessoa, André Salim Khayat, Raquel Carvalho Montenegro, Rommel Rodríguez Burbano, Maria Elisabete Amaral de Moraes
Publikováno v:
Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC
Pharmaceutics
Pharmaceutics, Vol 13, Iss 1604, p 1604 (2021)
Universidade Federal do Ceará (UFC)
instacron:UFC
Pharmaceutics
Pharmaceutics, Vol 13, Iss 1604, p 1604 (2021)
Cancer is still a major barrier to life expectancy increase worldwide, and hematologic neoplasms represent a relevant percentage of cancer incidence rates. Tumor dependence of continuous proliferative signals mediated through protein kinases overexpr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c475f6efc7328906d602dfe8c81a78
http://www.repositorio.ufc.br/handle/riufc/62960
http://www.repositorio.ufc.br/handle/riufc/62960
Autor:
Caio Bezerra Machado, Leidivan Sousa da Cunha, Jersey Heitor da Silva Maués, Flávia Melo Cunha de Pinho Pessoa, Marcelo Braga de Oliveira, Rodrigo Monteiro Ribeiro, Germison Silva Lopes, Manoel Odorico de Moraes Filho, Maria Elisabete Amaral de Moraes, André Salim Khayat, Caroline Aquino Moreira-Nunes
Publikováno v:
International Journal of Molecular Sciences. 23:5486
Human T cell leukemia virus type 1 (HTLV-1) was identified as the first pathogenic human retrovirus and is estimated to infect 5 to 10 million individuals worldwide. Unlike other retroviruses, there is no effective therapy to prevent the onset of the