Vitamin B12-induced spermatogenesis recovery in cimetidine-treated rats: effect on the spermatogonia number and sperm concentration

Autor: Flávia L Beltrame, Estela Sasso-Cerri

Publikováno v: Asian Journal of Andrology, Vol 19, Iss 5, Pp 567-572 (2017)

The H2-receptor antagonist cimetidine is an antiulcer drug also used for the treatment of cancer due to its antiangiogenic effect. However, this drug has caused structural changes in the seminiferous tubules. Vitamin B12 has been used as a therapeuti

Externí odkaz: https://doaj.org/article/be10a9fa87ae4cd1b60bc29bfe6510f0

Muscular atrophy, impaired epithelial autophagy and UCHL1 increase in androgen-deficient cauda epididymis

Autor: Flávia L. Beltrame, Paulo Sérgio Cerri, Estela Sasso-Cerri, Isadora Dantas Lunardi, Fabiane de Santi

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2020-12-12T02:03:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-05-01 In epididymis, cimetidine induces androgenic failure due to reduced sex hormone-binding globulin stromal levels and blockade of androgen rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb14a9c697b719fcee5c1e53de17858

Venlafaxine-induced adrenergic signaling stimulates Leydig cells steroidogenesis via Nur77 overexpression: A possible role of EGF

Autor: Beatriz M. Rodrigues, Flavia L. Lopes, Flávia L. Beltrame, Paulo Sérgio Cerri, Estela Sasso-Cerri, Natália Francisco Scaramele, Fabiane de Santi

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2022-04-28T19:48:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-15 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Ven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216361d4e51f6cb0ec2329d74b6e09bc
https://doi.org/10.1016/j.lfs.2021.120069

Vitamin B12 Prevents Cimetidine-Induced Androgenic Failure and Damage to Sperm Quality in Rats

Autor: Fabiane de Santi, Sandra Maria Miraglia, Estela Sasso-Cerri, Vanessa Vendramini, Regina Elizabeth Lourenço Cabral, Flávia L. Beltrame, Paulo Sérgio Cerri

Publikováno v: Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 10 (2019)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2019-10-06T16:49:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01 Cimetidine, used as an anti-ulcer and adjuvant treatment in cancer therapy, causes disorders in the male reproductive tract, including steroi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc784cfcf88657dc799811a96376fff
http://europepmc.org/articles/PMC6635670

Reduced levels of stromal sex hormone-binding globulin and androgen receptor dysfunction in the sperm storage region of the rat epididymis

Autor: Paulo Sérgio Cerri, Fabiane de Santi, Estela Sasso-Cerri, Flávia L. Beltrame, Barry T. Hinton

Publikováno v: Reproduction (Cambridge, England). 155(6)

The cauda epididymidis is the major sperm storage region whose androgenic supply, essential for the sperm viability, is provided by the vasculature and is dependent upon testosterone diffusion through the stromal tissue to reach the epithelial cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf493901118bf9bb5e392455368e3913
https://pubmed.ncbi.nlm.nih.gov/29748247