Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Flávia Almada do Carmo"'
Evaluation of Silybin Nanoparticles against Liver Damage in Murine Schistosomiasis mansoni Infection
Autor:
Daniel Figueiredo Vanzan, Ester Puna Goma, Fernanda Resende Locatelli, Thiago da Silva Honorio, Priscila de Souza Furtado, Carlos Rangel Rodrigues, Valeria Pereira de Sousa, Hilton Antônio Mata dos Santos, Flávia Almada do Carmo, Alice Simon, Alexandre dos Santos Pyrrho, António José Ribeiro, Lucio Mendes Cabral
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 618 (2024)
Silybin (SIB) is a hepatoprotective drug known for its poor oral bioavailability, attributed to its classification as a class IV drug with significant metabolism during the first-pass effect. This study explored the potential of solid lipid nanoparti
Externí odkaz:
https://doaj.org/article/fc038fd9e5b94caf9d99dd4e89dfb383
Autor:
Isadora Cabral Pinto, Cristal Cerqueira-Coutinho, Zaida Maria Faria de Freitas, Elisabete Pereira dos Santos, Flávia Almada do Carmo, Eduardo Ricci Junior
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 53, Iss 2 (2017)
ABSTRACT Diseases caused by insects are frequent in poor countries, leading to epidemic scenarios in urban areas; e.g., Dengue, Zika and Chikungunya. For this reason, the development of a safe and efficient topical formulation is essential. Ethyl but
Externí odkaz:
https://doaj.org/article/48c9e4fa90de4696a5a49f1d6b9b995f
Autor:
Maísa Teodoro Celestino, Uiaran de Oliveira Magalhães, Aline Guerra Manssour Fraga, Flávia Almada do Carmo, Viviane Lione, Helena Carla Castro, Valeria Pereira de Sousa, Carlos Rangel Rodrigues, Lucio Mendes Cabral
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 48, Iss 3, Pp 405-415 (2012)
Antioxidants are currently used as efficient excipients that delay or inhibit the oxidation process of molecules. Excipients are often associated with adverse reactions. Stability studies can guide the search for solutions that minimize or delay the
Externí odkaz:
https://doaj.org/article/d7bf93441ce74d8483450b193fdbbea4
Autor:
Lucio Mendes Cabral, Valeria Pereira de Sousa, Helvécio Vinícius Antunes Rocha, Valéria Sant'Anna Dantas Esteves, Carlos Rangel Rodrigues, Rita de Cássia da Silva Ascenção Barros, Helena Carla Rangel Castro, Thiago da Silva Honório, Flávia Almada do Carmo, Eduardo Costa Pinto
Publikováno v:
Pharmaceutics, Vol 4, Iss 3, Pp 430-441 (2012)
The purpose of this study was to propose an analytical procedure that provides the effects of particle size and surface area on dissolution of efavirenz. Five different batches obtained by different micronization processes and with different particle
Externí odkaz:
https://doaj.org/article/0eb3cadb313f4932a3a53c522f358fed
Autor:
Helena Keiko Toma, Ana Paula de Sá Pinto Abrahão Magalhães, Flávia Almada do Carmo, Claudia R. E. Mansur
Publikováno v:
Drug Development and Industrial Pharmacy. 47:825-837
The objective of this work was to prepare mucoadhesive buccal tablets containing nystatin and purified cashew gum for the treatment of oral candidiasis.Mucoadhesive buccal tablets containing the drug nystatin are an alternative to oral suspensions, w
Autor:
Luiz Cláudio Rodrigues Pereira da Silva, Alessandra Mendonça Teles de Souza, Valeria Pereira de Sousa, Dandara Paiva Barroso de Souza, Paloma Wetler Meireles, Douglas Escrivani de Oliveira, Marianne Grilo Rezende, Maria Paula Gonçalves Borsodi, Bartira Rossi-Bergmann, Lucio Mendes Cabral, Carlos Rangel Rodrigues, Gil Mendes Viana, Flávia Almada do Carmo
Publikováno v:
Current Drug Delivery. 17:694-702
Background: Leishmaniasis is a neglected tropical disease caused by protozoa of the genus Leishmania. Current treatments are restricted to a small number of drugs that display both severe side effects and a potential for parasites to develop resistan
Autor:
Ronyson Santos da Silva MOREIRA, Juliana Silva NOVAIS, Raphael Ferreira da SILVA, Raquel Pinto NUNES, Letícia Coli Louvisse de ABREU, Eliane Pedra DIAS, Helena Carla CASTRO, Flávia Almada do CARMO, Carlos Rangel RODRIGUES, Valeria Pereira de SOUSA, Lucio Mendes CABRAL
Publikováno v:
Food Science and Technology v.42 2022
Food Science and Technology (Campinas)
Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
instacron:SBCTA
Food Science and Technology (Campinas)
Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
instacron:SBCTA
The human oral cavity is colonized by a diversity of microorganisms living harmoniously. When an imbalance occurs in this population, also called dysbiosis, opportunistic microorganisms lead to oral infections. Nystatin, a traditional antifungal, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b3ce74d75d42a539e7f5818d5ee359
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000101256
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000101256
Autor:
Lucio Mendes Cabral, Érika Yoko Suzuki, Alice Simon, Thaisa Francielle Souza Domingos, Bárbara de Azevedo Abrahim Vieira, Alessandra Mendonça Teles de Souza, Carlos Rangel Rodrigues, Valeria Pereira de Sousa, Flávia Almada do Carmo
Publikováno v:
Mini reviews in medicinal chemistry.
Abstract: Prediction of pulmonary metabolites following inhalation of a locally acting pulmonary drug is essential to the successful development of novel inhaled medicines. The lungs present metabolic enzymes, therefore they influence drug disposal a
Autor:
Bianca Soares da Silva Marques, Silvia Leticia Ferreira de Oliveira Cunha, Luana dos Santos Guimarães, Janaina José dos Santos Machado, Luis Eduardo da Cruz, Flávia Almada do Carmo, Luiz Cláudio Rodrigues Pereira da Silva
Publikováno v:
Research, Society and Development; Vol. 11 No. 8; e33711830265
Research, Society and Development; Vol. 11 Núm. 8; e33711830265
Research, Society and Development; v. 11 n. 8; e33711830265
Research, Society and Development
Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
Research, Society and Development; Vol. 11 Núm. 8; e33711830265
Research, Society and Development; v. 11 n. 8; e33711830265
Research, Society and Development
Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
This work demonstrates the main elements of the risk management system at a Brazilian umbilical cord blood bank, taking into account the criticality and individuality of the procedures as well as regulatory and certifying agency guidelines. This stud
Autor:
Lucio Mendes Cabral, Carlos Rangel Rodrigues, Renata Ribeiro de Castro, Cláudia Martins, Alice Simon, Bruno Sarmento, Valeria Pereira de Sousa, Flávia Almada do Carmo
Publikováno v:
International journal of pharmaceutics. 602
Central nervous system tuberculosis (CNS-TB) is the most severe form of the disease especially due to the inability of therapeutics to cross the blood-brain barrier (BBB). Clofazimine (CFZ) stands out for presenting high in vitro activity against mul