Zobrazeno 1 - 10 of 304 pro vyhledávání: '"Fk, Stevenson"'
1
Antibodies to shared idiotypes as agents for analysis and therapy for human B cell tumors
Autor: Fk, Stevenson, Wrightham M, Mj, Glennie, Db, Jones, Ar, Cattan, Ten Feizi, Tj, Hamblin, Gt, Stevenson
Publikováno v: Europe PubMed Central
CIÊNCIAVITAE
Monoclonal anti-idiotypic antibodies generated against idiotypic immunoglobulin (Ig) of neoplastic B lymphocytes can be selected from growing hybridoma clones by their ability to recognize idiotypic but not normal IgM. This group of antibodies can be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145f0429e7c3e336fd1ad826878a1c14
https://doi.org/10.1182/blood.v68.2.430.bloodjournal682430
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2
Idiotype vaccination leads to the emergence of a stable surface Ig-negative variant of the mouse lymphoma BCL1, with different growth characteristics
Autor: Andrew George, Mb, Spellerberg, Fk, Stevenson
Publikováno v: Europe PubMed Central
Vaccination of mice with tumor-derived idiotypic IgM from the B cell lymphoma, BCL1, induces an anti-idiotypic immune response which suppresses tumor development. One of the mechanisms by which tumor cells can escape attack is by failing to express s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dd93df3233a3c3cb68116270ad52571b
https://pubmed.ncbi.nlm.nih.gov/3162250
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3
Idiotypic vaccination as a treatment for a B cell lymphoma
Autor: Andrew George, Sg, Folkard, Tj, Hamblin, Fk, Stevenson
Publikováno v: Europe PubMed Central
To develop a model for the active immunotherapy of human B cell malignancy we vaccinated tumor-bearing animals with a well defined tumor associated Ag, the idiotypic Ig. The tumor used was the mouse B cell lymphoma BCL1, a highly malignant tumor in w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7d3c3a96b7e80a3ed9f5cb51b86bb740
https://pubmed.ncbi.nlm.nih.gov/3049800
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6
Anti-idiotypic mechanisms involved in suppression of a mouse B cell lymphoma, BCL1
Autor: Andrew George, Al, Tutt, Fk, Stevenson
Publikováno v: Europe PubMed Central
Immunization of BALB/c mice with idiotypic IgM rescued by hybridization from the syngeneic BCL1 lymphoma protects specifically against challenge with tumor cells, with 83% surviving greater than 100 days compared with controls (38 +/- 10 days). Splee
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::26aeb2ae7c6ac00daba1a6e5864e764f
http://europepmc.org/abstract/med/3491853
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8
Recognition of a B cell lymphoma by anti-idiotypic T cells
Autor: Wilson A, Andrew George, Ca, King, Fk, Stevenson
Publikováno v: Europe PubMed Central
Idiotypic IgM derived from a B cell lymphoma can act as a tumor-associated Ag, in that immunization with this purified protein generates an anti-idiotypic immune response that specifically suppresses tumor development. Spleens of immune mice contain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b0a5f64c05899b2ef445f66c90668ddd
http://europepmc.org/abstract/med/2246520
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10
Editorial & Opinion
Introduction to a review series on the influence of the tumor microenvironment on the pathogenesis of B-cell lymphomas.
Autor: Steidl C, Stevenson FK
Publikováno v: Blood [Blood] 2024 Mar 21; Vol. 143 (12), pp. 1057-1058.
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