Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fjodor Merkuri"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Modifications to highly conserved developmental gene regulatory networks are thought to underlie morphological diversification in evolution and contribute to human congenital malformations. Relationships between gene expression and morpholog
Externí odkaz:
https://doaj.org/article/0154bdbf2a834df3ac7f2f5a4d822819
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Embryonic cells exhibit diverse metabolic states. Recent studies have demonstrated that metabolic reprogramming drives changes in cell identity by affecting gene expression. However, the connection between cellular metabolism and gene expres
Externí odkaz:
https://doaj.org/article/752bce13373f449083acf3f6decbbf07
Publikováno v:
Methods in Molecular Biology ISBN: 9781071628461
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e792407165504cdff787eb1090fdfe38
https://doi.org/10.1007/978-1-0716-2847-8_5
https://doi.org/10.1007/978-1-0716-2847-8_5
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2599
In vitro differentiation systems provide a flexible platform for understanding complex developmental processes. Here, we provide a comprehensive protocol for the preparation and analysis of ChIP-seq libraries for human-induced neural crest cells (hiN
Autor:
Jennifer L. Fish, Kym M. Boycott, Fjodor Merkuri, Peter C. Stirling, Rachel Aber, Matthew A. Lines, Eric Bareke, Marie-Claude Beauchamp, Anissa Djedid, Loydie A. Jerome-Majewska, Annie S. Tam, Jacek Majewski
Publikováno v:
Hum Mol Genet
EFTUD2 is mutated in patients with mandibulofacial dysostosis with microcephaly (MFDM). We generated a mutant mouse line with conditional mutation in Eftud2 and used Wnt1-Cre2 to delete it in neural crest cells. Homozygous deletion of Eftud2 causes b
Autor:
Todd Dowrey, Jennifer L. Fish, Yuri A. Zarate, Fjodor Merkuri, Evelyn E. Schwager, Julieann Duong
Publikováno v:
Bone
Special AT-rich sequence binding protein 2 (Satb2) is a matrix attachment region (MAR) binding protein. Satb2 impacts skeletal development by regulating gene transcription required for osteogenic differentiation. Although its role as a high-order tra
Autor:
Peter C. Stirling, Fjodor Merkuri, Kim M Boycott, Matthew A Lines, Jennifer L. Fish, Erik Bareke, Rachel Aber, Marie-Claude Beauchamp, Annie S. Tam, Anissa Djedid, Loydie A. Jerome-Majewska, Jacek Majewski
SummaryEFTUD2, a GTPase and core component of the splicesome, is mutated in patients with mandibulofacial dysostosis with microcephaly (MFDM). We generated a mutant mouse line with conditional mutation inEftud2and usedWnt1-Cre2to delete it in neural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa237e13d58caa8c54260068b71bcf1b
https://doi.org/10.1101/2020.09.22.308205
https://doi.org/10.1101/2020.09.22.308205