Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Fjodor A, Yousef Yengej"'
Tubuloid differentiation to model the human distal nephron and collecting duct in health and disease
Autor:
Fjodor A. Yousef Yengej, Carla Pou Casellas, Carola M.E. Ammerlaan, Charlotte J.A. Olde Hanhof, Emre Dilmen, Joep Beumer, Harry Begthel, Elise M.G. Meeder, Joost G. Hoenderop, Maarten B. Rookmaaker, Marianne C. Verhaar, Hans Clevers
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113614- (2024)
Summary: Organoid technology is rapidly gaining ground for studies on organ (patho)physiology. Tubuloids are long-term expanding organoids grown from adult kidney tissue or urine. The progenitor state of expanding tubuloids comes at the expense of di
Externí odkaz:
https://doaj.org/article/0b0f29d1d0104197b48e1e0d9de49d2d
Autor:
Rafael Soares Lindoso, Fjodor A. Yousef Yengej, Franziska Voellmy, Maarten Altelaar, Estela Mancheño Juncosa, Theano Tsikari, Carola M. E. Ammerlaan, Bas W. M. Van Balkom, Maarten B. Rookmaaker, Marianne C. Verhaar, Rosalinde Masereeuw
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract The prevalence of end-stage kidney disease (ESKD) is rapidly increasing with the need for regenerative therapies. Adult stem cell derived kidney tubuloids have the potential to functionally mimic the adult kidney tubule, but still lack the e
Externí odkaz:
https://doaj.org/article/331cae23c0ff4b0498dd6f9d94d91a78
Autor:
Adriana Martinez-Silgado, Fjodor A. Yousef Yengej, Jens Puschhof, Veerle Geurts, Charelle Boot, Maarten H. Geurts, Maarten B. Rookmaaker, Marianne C. Verhaar, Joep Beumer, Hans Clevers
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101639- (2022)
Summary: Intestinal organoids are three-dimensional cultures that resemble key aspects of the epithelium of origin. Here, we describe how to differentiate human small intestinal organoids by combining growth media variations and genetic engineering.
Externí odkaz:
https://doaj.org/article/dcf1297473074b90b8864176f730bcd6
Autor:
Judith Wienke, Saskia R. Veldkamp, Eva M. Struijf, Fjodor A. Yousef Yengej, M. Marlot van der Wal, Annet van Royen-Kerkhof, Femke van Wijk
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tissue-resident memory T cells (TRM) are suspected drivers of chronic inflammation, but their induction remains unclear. Since endothelial cells (EC) are obligate interaction partners for T cells trafficking into inflamed tissues, they may play a rol
Externí odkaz:
https://doaj.org/article/2d24555038ab49e1943cb86233e953cd
Autor:
Amer Jamalpoor, Charlotte AGH van Gelder, Fjodor A Yousef Yengej, Esther A Zaal, Sante P Berlingerio, Koenraad R Veys, Carla Pou Casellas, Koen Voskuil, Khaled Essa, Carola ME Ammerlaan, Laura Rita Rega, Reini EN van der Welle, Marc R Lilien, Maarten B Rookmaaker, Hans Clevers, Judith Klumperman, Elena Levtchenko, Celia R Berkers, Marianne C Verhaar, Maarten Altelaar, Rosalinde Masereeuw, Manoe J Janssen
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 7, Pp 1-20 (2021)
Abstract Nephropathic cystinosis is a severe monogenic kidney disorder caused by mutations in CTNS, encoding the lysosomal transporter cystinosin, resulting in lysosomal cystine accumulation. The sole treatment, cysteamine, slows down the disease pro
Externí odkaz:
https://doaj.org/article/824a49c53abd47ab8e331a84467b3272
Autor:
Maria J. Hagelaars, Fjodor A. Yousef Yengej, Marianne C. Verhaar, Maarten B. Rookmaaker, Sandra Loerakker, Carlijn V. C. Bouten
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Mechanical guidance of tissue morphogenesis is an emerging method of regenerative medicine that can be employed to steer functional kidney architecture for the purpose of bioartificial kidney design or renal tissue engineering strategies. In kidney m
Externí odkaz:
https://doaj.org/article/ab6fdcc3639349e0baccf883923b9005
Autor:
Fjodor A. Yousef Yengej, Jitske Jansen, Maarten B. Rookmaaker, Marianne C. Verhaar, Hans Clevers
Publikováno v:
Cells, Vol 9, Iss 6, p 1326 (2020)
In the past five years, pluripotent stem cell (PSC)-derived kidney organoids and adult stem or progenitor cell (ASC)-based kidney tubuloids have emerged as advanced in vitro models of kidney development, physiology, and disease. PSC-derived organoids
Externí odkaz:
https://doaj.org/article/050a4c9108de4b7989adce557c0ae243
Autor:
Arnaud Nicolas, Carola M. E. Ammerlaan, Linda Gijzen, Marianne K. Vormann, Paul Vulto, Maarten B. Rookmaaker, Frans Schutgens, Dorota Kurek, Hans Clevers, Fjodor A. Yousef Yengej, Henriëtte L. Lanz, Marianne C. Verhaar
Publikováno v:
Nature Protocols, 16(4), 2023-2050. Nature Publishing Group
Advanced in vitro kidney models are of great importance to the study of renal physiology and disease. Kidney tubuloids can be established from primary cells derived from adult kidney tissue or urine. Tubuloids are three-dimensional multicellular stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d9d6cfae864a7a1f35d11a739c7e16
https://doi.org/10.1038/s41596-020-00479-w
https://doi.org/10.1038/s41596-020-00479-w
Autor:
Charlotte J.A. Olde Hanhof, Jenny van der Wijst, Maarten B. Rookmaaker, Marianne C. Verhaar, Fjodor A. Yousef Yengej, Joost G. J. Hoenderop
Publikováno v:
Tissue Engineering. Part C: Methods, 27, 3, pp. 200-212
Tissue Engineering. Part C: Methods, 27, 200-212
Tissue Engineering. Part C: Methods, 27, 200-212
Item does not contain fulltext The kidneys are essential for maintaining electrolyte homeostasis. Blood electrolyte composition is controlled by active reabsorption and secretion processes in dedicated segments of the kidney tubule. Specifically, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f378c9ebfc03c21d9cb38729d04d77
https://repository.ubn.ru.nl/handle/2066/238804
https://repository.ubn.ru.nl/handle/2066/238804
Autor:
Linda, Gijzen, Fjodor A, Yousef Yengej, Frans, Schutgens, Marianne K, Vormann, Carola M E, Ammerlaan, Arnaud, Nicolas, Dorota, Kurek, Paul, Vulto, Maarten B, Rookmaaker, Henriette L, Lanz, Marianne C, Verhaar, Hans, Clevers
Publikováno v:
Nature protocols. 16(4)
Advanced in vitro kidney models are of great importance to the study of renal physiology and disease. Kidney tubuloids can be established from primary cells derived from adult kidney tissue or urine. Tubuloids are three-dimensional multicellular stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81a5beb23d23e1fc5c0ac7057b1d13a8
https://pubmed.ncbi.nlm.nih.gov/33674788
https://pubmed.ncbi.nlm.nih.gov/33674788