Effects of a peripherally acting µ-opioid receptor antagonist for the prevention of recurrent acute pancreatitis: study protocol for an investigator-initiated, randomized, placebo-controlled, double-blind clinical trial (PAMORA-RAP trial).

Autor: Cook ME; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark. m.cook@rn.dk.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. m.cook@rn.dk., Knoph CS; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark., Fjelsted CA; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark., Frøkjær JB; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.; Department of Radiology, Aalborg University Hospital, Aalborg, Denmark., Bilgrau AE; Department of Mathematical Sciences, Aalborg University, Aalborg, Denmark., Novovic S; Copenhagen University Hospital Hvidovre, Hvidovre, Denmark., Jørgensen MT; Department of Surgery, Odense Pancreas Centre (OPAC), HPB Section, Odense University Hospital, Odense, Denmark., Mortensen MB; Department of Surgery, Odense Pancreas Centre (OPAC), HPB Section, Odense University Hospital, Odense, Denmark., Nielsen LBJ; Digestive Disease Centre K, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark., Hadi A; Digestive Disease Centre K, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark., Berner-Hansen M; Digestive Disease Centre K, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark., Rutkowski W; Department for Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden., Vujasinovic M; Department for Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden., Löhr M; Department for Upper Abdominal Diseases, Karolinska University Hospital, Stockholm, Sweden., Drewes AM; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark., Olesen SS; Department of Gastroenterology and Hepatology, Centre for Pancreatic Diseases and Mech-Sense, Aalborg University Hospital, Aalborg, Denmark. soso@rn.dk.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. soso@rn.dk.

Publikováno v: Trials [Trials] 2023 May 01; Vol. 24 (1), pp. 301. Date of Electronic Publication: 2023 May 01.

Simple Quantitative Sensory Testing Reveals Paradoxical Co-existence of Hypoesthesia and Hyperalgesia in Diabetes.

Autor: Hansen LEM; Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark.; Centre for Clinical Research, North Denmark Regional Hospital, Hjoerring, Denmark., Fjelsted CA; Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Clinical Institute, Aalborg University, Aalborg, Denmark., Olesen SS; Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Clinical Institute, Aalborg University, Aalborg, Denmark.; Centre of Pancreatic Diseases, Aalborg University Hospital, Aalborg, Denmark., Phillips AE; Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States., Faghih M; Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, United States., Wegeberg AM; Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark., Drewes AM; Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Clinical Institute, Aalborg University, Aalborg, Denmark.; Centre of Pancreatic Diseases, Aalborg University Hospital, Aalborg, Denmark.; Steno Diabetes Center Nordjylland, Aalborg, Denmark., Brock C; Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark.; Department of Clinical Medicine, Clinical Institute, Aalborg University, Aalborg, Denmark.; Steno Diabetes Center Nordjylland, Aalborg, Denmark.

Publikováno v: Frontiers in pain research (Lausanne, Switzerland) [Front Pain Res (Lausanne)] 2021 Jun 28; Vol. 2, pp. 701172. Date of Electronic Publication: 2021 Jun 28 (Print Publication: 2021).