Výsledky vyhledávání - "Fjalar, Kristjansson"

Unsuspected poor metabolizer phenotypes of fluoxetine in bioavailability/bioequivalence studies from an Indian population perspective

Autor: Balakrishna Pai, Sandhya Ravi, Fjalar Kristjansson, Mani Kandasamy, Krishnanand Tripathy, Nuggehally R. Srinivas, Narendra Kamath, Saral Thangam

Publikováno v: Arzneimittelforschung. 60:12-21

Fluoxetine, belonging to the class of selective serotonin uptake inhibitors, has been extensively used for the treatment of depression and other psychiatry related disorders. Fluoxetine (CAS 59333-67-4) is a substrate of polymorphic cytochrome P450 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9f0ae298e569a2c9363bb7f58d85a27
https://doi.org/10.1055/s-0031-1296243

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Unsuspected poor metabolizer phenotypes of fluoxetine in bioavailability/bioequivalence studies from an indian population perspective. Retrospective pharmacokinetic data evaluation

Autor: Mani, Kandasamy, Krishnanand, Tripathy, Sandhya, Ravi, Narendra, Kamath, Balakrishna, Pai, Nuggehally R, Srinivas, Fjalar, Kristjansson, Saral, Thangam

Publikováno v: Arzneimittel-Forschung. 60(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::20247153c6715eeeb8d76b7c5bc8a906
https://pubmed.ncbi.nlm.nih.gov/20184222

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Influence of number of calibration standards within a defined range on pharmacokinetic disposition-case studies with omeprazole and clopidogrel carboxylic acid

Autor: Nuggehally R. Srinivas, Fjalar Kristjansson, Radha Shekar, Balakrishna Pai, Anil Kumar, Henry John Baptist D'Souza

Publikováno v: Biomedical Chromatography.

While the practice of using a smaller number of non-zero standards (typically seven to eight) has not been entertained in routine bioanalytical work, it is important to innovate and be pragmatic about minimizing the number of calibration standards to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88fbd74c831422eedc7ea6dc0ab45eb
https://doi.org/10.1002/bmc.1324

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Sensitivity enhancement and matrix effect evaluation during summation of multiple transition pairs-case studies of clopidogrel and ramiprilat

Autor: Nuggehally R. Srinivas, J. Manjunath Swamy, Narendra Kamath, Anil Kumar Radha Shekar, Fjalar Kristjansson

Publikováno v: Biomedical Chromatography.

Sensitivity enhancement via summation of multiple MRM transition pairs is gaining popularity in tandem mass spectrometric assays. Numerous validation experiments describing the assays for two model substrates, clopidogrel and ramiprilat, were perform

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e6bb9cf65a548e2aec3abbc2746e18
https://doi.org/10.1002/bmc.1322

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An investigation on possible oligomer formation in pharmaceutical formulations of cisplatin

Autor: Larry A. Sternson, Siegfried Lindenbaum, Fjalar Kristjansson

Publikováno v: International Journal of Pharmaceutics. 41:67-74

Concern has been raised that the anti-neoplastic agent, cisplatin, when formulated in isotonic sodium chloride solution may degrade to di-μ-hydroxo-bis( cis -diammineplatinum(II)) 4 and tri-μ-hydroxo-tris( cis -diammineplatinum(II)) 5 which have be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f69f6bf9d912fa110069e66d0a535aae
https://doi.org/10.1016/0378-5173(88)90137-8

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