Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Fitzroy W Dawkins"'
Autor:
Paul C Adams, James C Barton, Gordon D McLaren, Ronald T Acton, Mark Speechley, Christine E McLaren, David M Reboussin, Catherine Leiendecker-Foster, Emily L Harris, Beverly M Snively, Thomas Vogt, Phyliss Sholinsky, Elizabeth Thomson, Fitzroy W Dawkins, Victor R Gordeuk, John H Eckfeldt
Publikováno v:
Canadian Journal of Gastroenterology, Vol 23, Iss 11, Pp 769-772 (2009)
BACKGROUND: The HEmochromatosis and IRon Overload Screening (HEIRS) Study provided data on a racially, ethnically and geographically diverse cohort of participants in North America screened from primary care populations.
Externí odkaz:
https://doaj.org/article/6e53e75d0a134cf2a8ea25d468034d8f
Autor:
Gordon D McLaren, Christine E McLaren, Paul C Adams, James C Barton, David M Reboussin, Victor R Gordeuk, Ronald T Acton, Emily L Harris, Mark R Speechley, Phyliss Sholinsky, Fitzroy W Dawkins, Beverly M Snively, Thomas M Vogt, John H Eckfeldt, for the Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators
Publikováno v:
Canadian Journal of Gastroenterology, Vol 22, Iss 11, Pp 923-930 (2008)
BACKGROUND: Patients with hemochromatosis may suffer organ damage from iron overload, often with serious clinical consequences.
Externí odkaz:
https://doaj.org/article/3c6c7556d4464ce498ebe6998618e4c6
Autor:
James C. Barton, Victor R. Gordeuk, Beverly M. Snively, Phyliss Sholinsky, Christine E. McLaren, Ronald T. Acton, John H. Eckfeldt, Paul C. Adams, Gordon D. McLaren, Fitzroy W. Dawkins, Mark Speechley, David M. Reboussin, Emily L. Harris, Thomas M. Vogt
Publikováno v:
Canadian Journal of Gastroenterology, Vol 22, Iss 11, Pp 923-930 (2008)
BACKGROUND: Patients with hemochromatosis may suffer organ damage from iron overload, often with serious clinical consequences.OBJECTIVE: To assess prevalences of self-reported symptoms and clinical signs and conditions in persons homozygous for the
Autor:
Paul C. Adams, David M. Reboussin, Jacob A. Reiss, Richard D. Press, John H. Eckfeldt, Fitzroy W. Dawkins, Victor R. Gordeuk, Gordon D. McLaren, Catherine Leiendecker-Foster, Christine E. McLaren, James C. Barton, Ronald T. Acton, Laura C. Lovato, Mark Speechley
Publikováno v:
Genetic Testing. 11:269-275
We characterized HFE C282Y homozygotes aged 25-29 years in the HEmochromatosis and IRon Overload Screening (HEIRS) Study using health questionnaire responses, transferrin saturation (TfSat), serum ferritin (SF), and HFE genotyping. In eight homozygot
Autor:
James C. Barton, Beverly M. Snively, Catherine Leiendecker-Foster, Gordon D. McLaren, David M. Reboussin, Fitzroy W. Dawkins, Richard D. Press, Paul C. Adams, Ronald T. Acton, Victor R. Gordeuk, Mark Speechley, Charles A. Rivers, Christine E. McLaren
Publikováno v:
Blood Cells, Molecules, and Diseases. 38:247-252
The ferroportin (FPN1) Q248H polymorphism has been associated with increased serum ferritin (SF) levels in sub-Saharan Africans and in African Americans (AA). AA participants of the HEIRS Study who did not have HFE C282Y or H63D who had elevated init
Autor:
Victor R. Gordeuk, David M. Reboussin, Mark Speechley, Emily L. Harris, Paul C. Adams, Christine E. McLaren, Phyliss Sholinsky, Gordon D. McLaren, Beverly M. Snively, Fitzroy W. Dawkins, Ronald T. Acton, Joan Holup, James C. Barton, John H. Eckfeldt, Catherine Leiendecker-Foster, Elizabeth J. Thomson
Publikováno v:
New England Journal of Medicine. 352:1769-1778
background Iron overload and hemochromatosis are common, treatable conditions. HFE genotypes, levels of serum ferritin, transferrin saturation values, and self-reported medical history were studied in a multiethnic primary care population. methods Pa
Autor:
Stephen Clarke, Ron H.N. van Schaik, Paul W. Schenk, Hans Gelderblom, Michael A. Carducci, Alex Sparreboom, Kellie A. Charles, Laurent P. Rivory, Kimberly Dinh, Fitzroy W. Dawkins, Wilfried J. Graveland, William P. McGuire, Albert J. ten Tije, Sharyn D. Baker, Jaap Verweij
Publikováno v:
Clinical Cancer Research, 10, 8341-8350. American Association for Cancer Research Inc.
Purpose: The purpose is to identify the demographic, physiologic, and inheritable factors that influence CYP3A activity in cancer patients Experimental Design: A total of 134 patients (62 females; age range, 26 to 83 years) underwent the erythromycin
Autor:
Fitzroy W. Dawkins, Robert L. DeWitty, Lucile L. Adams-Campbell, Chiledum Ahaghotu, Robert Gooding, Melvin Gaskins, Octavius Polk, Duane T. Smoot
Publikováno v:
Journal of Clinical Oncology. 22:730-734
Purpose African Americans have the highest cancer mortality rates and poorest survival and are more often uninsured and underinsured compared with other ethnic groups. Minority participation in clinical trials has traditionally been low, with reports
Autor:
Elizabeth J. Thomson, Paul C. Adams, Fitzroy W. Dawkins, David M. Reboussin, James C. Barton, Emily L. Harris, Catherine Leiendecker-Foster, Nancy Press, Beverly G. Mellen, Phyliss Sholinsky, Christine E. McLaren, John H. Eckfeldt, Victor R. Gordeuk, Gordon D. McLaren, Mark Speechley, Ronald T. Acton, Ann P. Walker
Publikováno v:
The American Journal of the Medical Sciences. 325:53-62
Background The HEIRS Study will evaluate the prevalence, genetic and environmental determinants, and potential clinical, personal, and societal impact of hemochromatosis and iron overload in a multiethnic, primary care-based sample of 100,000 adults
Publikováno v:
Cancer Causes and Control. 13:543-549
Objective: Compromised breast cancer survival in African American women is well established. Factors associated with poorer survival in this group are not fully elucidated. This analysis examined the influence of alcohol consumption on breast cancer