Modulation of the cell membrane lipid milieu by peroxisomal β-oxidation induces Rho1 signaling to trigger inflammatory responses.

Autor: Nath AS; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Parsons BD; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Makdissi S; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Chilvers RL; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Mu Y; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Weaver CM; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Euodia I; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Fitze KA; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Long J; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Scur M; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Mackenzie DP; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Makrigiannis AP; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada., Pichaud N; Université de Moncton, Department of Chemistry and Biochemistry, Moncton, NB E1A 3E9, Canada; New Brunswick Centre for Precision Medicine (NBCPM), Moncton, NB E1A 3E9, Canada., Boudreau LH; Université de Moncton, Department of Chemistry and Biochemistry, Moncton, NB E1A 3E9, Canada; New Brunswick Centre for Precision Medicine (NBCPM), Moncton, NB E1A 3E9, Canada., Simmonds AJ; University of Alberta, Department of Cell Biology, Edmonton, AB T6G 2H7, Canada., Webber CA; University of Alberta, Department of Cell Biology, Edmonton, AB T6G 2H7, Canada., Derfalvi B; Dalhousie University, Department of Pediatrics, Halifax, NS B3K 6R8, Canada., Hammon Y; INSERM au Centre d'Immunologie de Marseille Luminy, Marseille 13288, France., Rachubinski RA; University of Alberta, Department of Cell Biology, Edmonton, AB T6G 2H7, Canada., Di Cara F; Dalhousie University, Department of Microbiology and Immunology, Halifax, NS B3K 6R8, Canada; Dalhousie University, Department of Pediatrics, Halifax, NS B3K 6R8, Canada. Electronic address: dicara@dal.ca.

Publikováno v: Cell reports [Cell Rep] 2022 Mar 01; Vol. 38 (9), pp. 110433.