Zobrazeno 1 - 10
of 872
pro vyhledávání: '"Fitness effects"'
Autor:
Kassen, Rees, author
Publikováno v:
Experimental Evolution and the Nature of Biodiversity, 2024, ill.
Externí odkaz:
https://doi.org/10.1093/oso/9780192898661.003.0002
Autor:
Lynch, Michael R., author
Publikováno v:
Evolutionary Cell Biology : The Origins of Cellular Architecture, 2024, ill.
Externí odkaz:
https://doi.org/10.1093/oso/9780192847287.003.0005
Autor:
Lynch, Michael R., author
Publikováno v:
Evolutionary Cell Biology : The Origins of Cellular Architecture, 2024, ill.
Externí odkaz:
https://doi.org/10.1093/oso/9780192847287.003.0012
Autor:
Somya Mani, Tsvi Tlusty
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Over evolutionary timescales, genomic loci can switch between functional and non-functional states through processes such as pseudogenization and de novo gene birth. Particularly, de novo gene birth is a widespread process, and ma
Externí odkaz:
https://doaj.org/article/47b6320a4f7a4848b8040bef9b4667d5
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Publikováno v:
eLife, Vol 12 (2023)
Causal loss-of-function (LOF) variants for Mendelian and severe complex diseases are enriched in 'mutation intolerant' genes. We show how such observations can be interpreted in light of a model of mutation-selection balance and use the model to rela
Externí odkaz:
https://doaj.org/article/7cfc56c5bf724df09e38c99b0144778c
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss , Pp 168-175 (2021)
Infections by parasitic nematodes cause large health and economic burdens worldwide. We use anthelmintic drugs to reduce these infections. However, resistance to anthelmintic drugs is extremely common and increasing worldwide. It is essential to unde
Externí odkaz:
https://doaj.org/article/c9baf924d50d469899b636e4ff1e9d93
Autor:
Adandé A. Medjigbodo, Luc S. Djogbénou, Oswald Y. Djihinto, Romaric B. Akoton, Emmanuella Abbey, Rosaria M. Kakossou, Eric G. Sonounameto, Esther B. J. Salavi, Laurette Djossou, Athanase Badolo
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-10 (2021)
Abstract Background Existing mechanisms of insecticide resistance are known to help the survival of mosquitoes following contact with chemical compounds, even though they could negatively affect the life-history traits of resistant malaria vectors. I
Externí odkaz:
https://doaj.org/article/b35f168a33124b8494460c10bf731690
Quantitative benzimidazole resistance and fitness effects of parasitic nematode beta-tubulin alleles
Autor:
Clayton M. Dilks, Steffen R. Hahnel, Qicong Sheng, Lijiang Long, Patrick T. McGrath, Erik C. Andersen
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss , Pp 28-36 (2020)
Infections by parasitic nematodes inflict a huge burden on the health of humans and livestock throughout the world. Anthelmintic drugs are the first line of defense against these infections. Unfortunately, resistance to these drugs is rampant and con
Externí odkaz:
https://doaj.org/article/8ba56406d5eb4071851347b0bb36e13a
Publikováno v:
BMC Microbiology, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Horizontal gene transfer, the acquisition of genes across species boundaries, is a major source of novel phenotypes that enables microbes to rapidly adapt to new environments. How the transferred gene alters the growth – fitness
Externí odkaz:
https://doaj.org/article/30028a9e65f746748e2979231bc9507f