Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Fitnat H. Yildiz"'
Autor:
Anna Potapova, William Garvey, Peter Dahl, Shuaiqi Guo, Yunjie Chang, Carmen Schwechheimer, Michael A. Trebino, Kyle A. Floyd, Brett S. Phinney, Jun Liu, Nikhil S. Malvankar, Fitnat H. Yildiz
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Biofilms are matrix-encased microbial communities that increase the environmental fitness and infectivity of many human pathogens including Vibrio cholerae. Biofilm matrix assembly is essential for biofilm formation and function. Known compo
Externí odkaz:
https://doaj.org/article/90ccdbc693ef447e9729b2cff902d02c
Autor:
Jennifer K. Teschler, Eva Jiménez-Siebert, Hannah Jeckel, Praveen K. Singh, Jin Hwan Park, Stefan Pukatzki, Carey D. Nadell, Knut Drescher, Fitnat H. Yildiz
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT The human pathogen Vibrio cholerae grows as biofilms, communities of cells encased in an extracellular matrix. When growing in biofilms, cells compete for resources and space. One common competitive mechanism among Gram-negative bacteria is
Externí odkaz:
https://doaj.org/article/964f624d3b414a30862f81f9ffbffbd6
Autor:
Kyle A. Floyd, Calvin K. Lee, Wujing Xian, Mahmoud Nametalla, Aneesa Valentine, Benjamin Crair, Shiwei Zhu, Hannah Q. Hughes, Jennifer L. Chlebek, Daniel C. Wu, Jin Hwan Park, Ali M. Farhat, Charles J. Lomba, Courtney K. Ellison, Yves V. Brun, Javier Campos-Gomez, Ankur B. Dalia, Jun Liu, Nicolas Biais, Gerard C. L. Wong, Fitnat H. Yildiz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Biofilm formation by Vibrio cholerae is regulated by c-di-GMP and requires the type IV MSHA pilus. Here, Floyd et al. show that the MSHA pilus is a dynamic system, and that both extension and retraction are directly controlled by c-di-GMP via regulat
Externí odkaz:
https://doaj.org/article/cabf8badabb34c2f9c45f7702f8ed372
Autor:
Giordan Kitts, Krista M. Giglio, David Zamorano-Sánchez, Jin Hwan Park, Loni Townsley, Richard B. Cooley, Benjamin R. Wucher, Karl E. Klose, Carey D. Nadell, Fitnat H. Yildiz, Holger Sondermann
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT The dinucleotide second messenger c-di-GMP has emerged as a central regulator of reversible cell attachment during bacterial biofilm formation. A prominent cell adhesion mechanism first identified in pseudomonads combines two c-di-GMP-mediat
Externí odkaz:
https://doaj.org/article/9a8a543adaa141dcaa3c9dfe3f2eca0c
Publikováno v:
Molecules, Vol 26, Iss 15, p 4582 (2021)
Biofilms, the predominant growth mode of microorganisms, pose a significant risk to human health. The protective biofilm matrix, typically composed of exopolysaccharides, proteins, nucleic acids, and lipids, combined with biofilm-grown bacteria’s h
Externí odkaz:
https://doaj.org/article/0c3f799a682545b89c7f415a7e10e07f
Autor:
David Zamorano-Sánchez, Wujing Xian, Calvin K. Lee, Mauro Salinas, Wiriya Thongsomboon, Lynette Cegelski, Gerard C. L. Wong, Fitnat H. Yildiz
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Vibrio cholerae biofilm formation and associated motility suppression are correlated with increased concentrations of cyclic diguanylate monophosphate (c-di-GMP), which are in turn driven by increased levels and/or activity of diguanylate cy
Externí odkaz:
https://doaj.org/article/1799c15680334db5b2cd9be4e80e0196
Autor:
Yu-Chuan Wang, Ko-Hsin Chin, Zhi-Le Tu, Jin He, Christopher J. Jones, David Zamorano Sanchez, Fitnat H. Yildiz, Michael Y. Galperin, Shan-Ho Chou
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Cyclic-di-GMP is a bacterial second messenger that binds to the regulatory domain of ATPases of some bacteria. Here, the authors report the crystal structure of this interaction, identify a cyclic-di-GMP binding mode, and show that this interaction m
Externí odkaz:
https://doaj.org/article/69073df07bab47839c41ed1768992ae2
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7 (2012)
Externí odkaz:
https://doaj.org/article/ac1f232457004c61aeb87a852c1642dd
Publikováno v:
Annual review of microbiology. 76
Biofilms are a widely observed growth mode in which microbial communities are spatially structured and embedded in a polymeric extracellular matrix. Here, we focus on the model bacterium
Autor:
Janne G. Thöming, Anna Dragoš, Daniel K. H. Rode, Victor Sourjik, Lucia Vidakovic, Knut Drescher, Niklas Netter, Susanne Häussler, Praveen K. Singh, Ákos T. Kovács, Miriam Bayer, Sanika Vaidya, Olga Lamprecht, Carey D. Nadell, Fitnat H. Yildiz, Francisco Díaz-Pascual, Eric Jelli, Hannah Jeckel, Jiunn C. N. Fong, Raimo Hartmann
Publikováno v:
Nature microbiology
England
Nature Microbiology
Hartmann, R, Jeckel, H, Jelli, E, Singh, P K, Vaidya, S, Bayer, M, Rode, D K H, Vidakovic, L, Díaz-Pascual, F, Fong, J C N, Dragoš, A, Lamprecht, O, Thöming, J G, Netter, N, Häussler, S, Nadell, C D, Sourjik, V, Kovács, Á T, Yildiz, F H & Drescher, K 2021, ' Quantitative image analysis of microbial communities with BiofilmQ ', Nature Microbiology, vol. 6, pp. 151-156 . https://doi.org/10.1038/s41564-020-00817-4
England
Nature Microbiology
Hartmann, R, Jeckel, H, Jelli, E, Singh, P K, Vaidya, S, Bayer, M, Rode, D K H, Vidakovic, L, Díaz-Pascual, F, Fong, J C N, Dragoš, A, Lamprecht, O, Thöming, J G, Netter, N, Häussler, S, Nadell, C D, Sourjik, V, Kovács, Á T, Yildiz, F H & Drescher, K 2021, ' Quantitative image analysis of microbial communities with BiofilmQ ', Nature Microbiology, vol. 6, pp. 151-156 . https://doi.org/10.1038/s41564-020-00817-4
Biofilms are microbial communities that represent a highly abundant form of microbial life on Earth. Inside biofilms, phenotypic and genotypic variations occur in three-dimensional space and time; microscopy and quantitative image analysis are theref