Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Fitim Berisha"'
Autor:
Matthew W. Fittall, William Mifsud, Nischalan Pillay, Hongtao Ye, Anna-Christina Strobl, Annelien Verfaillie, Jonas Demeulemeester, Lei Zhang, Fitim Berisha, Maxime Tarabichi, Matthew D. Young, Elena Miranda, Patrick S. Tarpey, Roberto Tirabosco, Fernanda Amary, Agamemnon E. Grigoriadis, Michael R. Stratton, Peter Van Loo, Cristina R. Antonescu, Peter J. Campbell, Adrienne M. Flanagan, Sam Behjati
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-6 (2018)
FOS has been linked to bone tumour pathogenesis, and viral homologue v-fos causes osteosarcoma in mice. Here, the authors report rearrangement of FOS and its paralogue FOSB in osteoblastoma and osteoid osteoma, revealing human bone tumours that are d
Externí odkaz:
https://doaj.org/article/e874f5cac91c4dfcb8f739743873d777
Autor:
Roberto Jose Diaz, Mustafa Guduk, Rocco Romagnuolo, Christian A. Smith, Paul Northcott, David Shih, Fitim Berisha, Adrienne Flanagan, David G. Munoz, Michael D. Cusimano, M. Necmettin Pamir, James T. Rutka
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 9, Pp 788-798 (2012)
Chordoma is a rare tumor arising in the sacrum, clivus, or vertebrae. It is often not completely resectable and shows a high incidence of recurrence and progression with shortened patient survival and impaired quality of life. Chemotherapeutic option
Externí odkaz:
https://doaj.org/article/69c16036d20d4c7fb2f982fdb6e84f4e
Autor:
Elena Miranda, Roberto Tirabosco, Paul Cool, Daniel Baumhoer, Fernanda Amary, Lucia Cottone, Paul O'Donnell, Luis Perez-Casanova, William Aston, Maia Rocha, Hongtao Ye, Anna-Christina Strobl, Nischalan Pillay, Fitim Berisha, Adrienne M. Flanagan, Edward Hookway
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
A fusion between fibronectin 1 (FN1) and activin receptor 2A (ACVR2A) has been reported previously in isolated cases of the synovial chondromatosis. To analyze further and validate the findings, we performed FISH and demonstrated recurrent FN1-ACVR2A
Autor:
Roberto Tirabosco, Fernanda Amary, Hongtao Ye, Paul Cool, Craig Gerrand, Nischalan Pillay, Adrienne M. Flanagan, Paul O'Donnell, Fitim Berisha, Daniel Baumhoer, Eva Markert, Daniel Lindsay
Publikováno v:
American Journal of Surgical Pathology. 43:1661-1667
Osteoblastoma and osteoid osteoma together are the most frequent benign bone-forming tumor, arbitrarily separated by size. In some instances, it can be difficult to differentiate osteoblastoma from osteosarcoma. Following our recent description of FO
Autor:
Christopher D. Steele, Maxime Tarabichi, Dahmane Oukrif, Amy P. Webster, Hongtao Ye, Matthew Fittall, Patrick Lombard, Iñigo Martincorena, Patrick S. Tarpey, Grace Collord, Kerstin Haase, Sandra J. Strauss, Fitim Berisha, Heli Vaikkinen, Pawan Dhami, Marnix Jansen, Sam Behjati, M. Fernanda Amary, Roberto Tirabosco, Andrew Feber, Peter J. Campbell, Ludmil B. Alexandrov, Peter Van Loo, Adrienne M.
Publikováno v:
Cancer Cell
Autor:
Nischalan Pillay, Michael R. Stratton, Lei Zhang, William Mifsud, Matthew Fittall, Roberto Tirabosco, Patrick S. Tarpey, Hongtao Ye, Elena Miranda, Sam Behjati, Jonas Demeulemeester, Cristina R. Antonescu, Fernanda Amary, Peter Van Loo, Annelien Verfaillie, Peter J. Campbell, Anna Christina Strobl, Agamemnon E. Grigoriadis, Maxime Tarabichi, Fitim Berisha, Matthew D. Young, Adrienne M. Flanagan
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-6 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-6 (2018)
The transcription factor FOS has long been implicated in the pathogenesis of bone tumours, following the discovery that the viral homologue, v-fos, caused osteosarcoma in laboratory mice. However, mutations of FOS have not been found in human bone-fo
Autor:
Christopher D. Steele, Fitim Berisha, Adrienne M. Flanagan, Inigo Martincorena, Sam Behjati, Grace Collord, Peter J. Campbell, Maxime Tarabichi, Peter Van Loo, Nischalan Pillay, M Fernanda Amary, Marnix Jansen, Roberto Tirabosco, Patrick Lombard, Patrick S. Tarpey, Ludmil B. Alexandrov, Dahmane Oukrif, Sandra J. Strauss, Hongtao Ye, Matthew Fittall
Publikováno v:
SSRN Electronic Journal.
Undifferentiated sarcomas (USARC) of adults are diverse, rare and aggressive soft tissue cancers. Recent efforts have confirmed that USARC exhibit one of the highest burdens of structural aberrations across human cancer. Here, we sought to unravel th
Autor:
Manu Gupta, Fernanda Amary, Alice Gutteridge, Paul O'Donnell, Rebecca Gibbons, Roberto Tirabosco, Daniel Baumhoer, Hongtao Ye, Fitim Berisha, Adrienne M. Flanagan
Publikováno v:
The American Journal of Surgical Pathology
Giant cell tumor of bone (GCTB) is a locally aggressive subarticular tumor. Having recently reported that H3.3 G34W mutations are characteristic of this tumor type, we have now investigated the sensitivity and specificity of the anti-histone H3.3 G34
Autor:
Nischalan Pillay, Stephen Henderson, Nadege Presneau, Claudio D. Stern, Fiona C. Wardle, Andrew C. Nelson, Derek L. Stemple, Adrienne M. Flanagan, Roberto Tirabosco, Dina Halai, Fitim Berisha, Paul Flicek
Publikováno v:
The Journal of Pathology. 228:274-285
Chordoma is a rare malignant tumour of bone, the molecular marker of which is the expression of the transcription factor, brachyury. Having recently demonstrated that silencing brachyury induces growth arrest in a chordoma cell line, we now seek to i
Autor:
Rosemary E. Gale, Valeria Fantin, Andrew Futreal, Peter J. Campbell, Nadege Presneau, Roberto Tirabosco, Claire Green, Dina Halai, Malihe Eskandarpour, Kimberly Straley, Fiona Bonar, Samira B Lobo, Stephen Damato, Adrienne M. Flanagan, Stan McCarthy, Fitim Berisha, Will Aston, M Fernanda Amary
Publikováno v:
Nature Genetics. 43:1262-1265
Ollier disease and Maffucci syndrome are characterized by multiple central cartilaginous tumors that are accompanied by soft tissue hemangiomas in Maffucci syndrome. We show that in 37 of 40 individuals with these syndromes, at least one tumor has a