Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Fisun Hamaratoglu"'
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009138 (2020)
[This corrects the article DOI: 10.1371/journal.pgen.1008396.].
Externí odkaz:
https://doaj.org/article/3ccc32aeb23b49cd891e59c696ad45cc
Cell elimination strategies upon identity switch via modulation of apterous in Drosophila wing disc.
Autor:
Olga Klipa, Fisun Hamaratoglu
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008573 (2019)
The ability to establish spatial organization is an essential feature of any developing tissue and is achieved through well-defined rules of cell-cell communication. Maintenance of this organization requires elimination of cells with inappropriate po
Externí odkaz:
https://doaj.org/article/e8d84236c7c94c6c89abda9f602e7c66
Publikováno v:
PLoS Genetics, Vol 15, Iss 9, p e1008396 (2019)
The interplay between signalling pathways and metabolism is crucial for tissue growth. Yet, it remains poorly understood. Here, we studied the consequences of modulating iron metabolism on the growth of Drosophila imaginal discs. We find that reducin
Externí odkaz:
https://doaj.org/article/a4d79892ae2b46b7920315b47f74dbbc
Autor:
Dimitri Bieli, Oguz Kanca, David Requena, Fisun Hamaratoglu, Daryl Gohl, Paul Schedl, Markus Affolter, Matthew Slattery, Martin Müller, Carlos Estella
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005376 (2015)
The subdivision of cell populations in compartments is a key event during animal development. In Drosophila, the gene apterous (ap) divides the wing imaginal disc in dorsal vs ventral cell lineages and is required for wing formation. ap function as a
Externí odkaz:
https://doaj.org/article/7069a87b72ee4cd794133f0b9a4ae181
Autor:
Fisun Hamaratoglu, Aitana Morton de Lachapelle, George Pyrowolakis, Sven Bergmann, Markus Affolter
Publikováno v:
PLoS Biology, Vol 9, Iss 10, p e1001182 (2011)
The wing of the fruit fly, Drosophila melanogaster, with its simple, two-dimensional structure, is a model organ well suited for a systems biology approach. The wing arises from an epithelial sac referred to as the wing imaginal disc, which undergoes
Externí odkaz:
https://doaj.org/article/73b462f8f8d047eea40e0a4c944d13b6
Elimination Of Aberrantly Specified Cell Clones Is Independent Of Interfacial Myosin II Accumulation
Autor:
Fisun Hamaratoglu, Olga Klipa
Spatial organization of differently fated cells within an organ is essential and needs to be maintained during development. This is largely implemented via compartment boundaries that serve as barriers between distinct cell types. Biased accumulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fea396a7dfc45f5e0450bf4638e2e2b
https://doi.org/10.1101/2021.05.14.444162
https://doi.org/10.1101/2021.05.14.444162
Autor:
Mardelle Atkins, Fisun Hamaratoglu
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 4580, p 4580 (2020)
Volume 21
Issue 13
International Journal of Molecular Sciences, Vol 21, Iss 4580, p 4580 (2020)
Volume 21
Issue 13
Can hyperactivation of a few key signaling effectors be the underlying reason for the majority of epithelial cancers despite different driver mutations? Here, to address this question, we use the Drosophila model, which allows analysis of gene expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c30d0168a5b26f4df02cd846470be53
http://europepmc.org/articles/PMC7370090
http://europepmc.org/articles/PMC7370090
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 15, Iss 9, p e1008396 (2019)
PLoS Genetics, Vol 15, Iss 9, p e1008396 (2019)
The interplay between signalling pathways and metabolism is crucial for tissue growth. Yet, it remains poorly understood. Here, we studied the consequences of modulating iron metabolism on the growth of Drosophila imaginal discs. We find that reducin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca1d1c262c2c24c31a9de7dd92ee8e4
https://pubmed.ncbi.nlm.nih.gov/33057412
https://pubmed.ncbi.nlm.nih.gov/33057412
Autor:
Lucia Romanelli, Jelle Jacobs, Jana Mach, Mardelle Atkins, Delphine Potier, Georg Halder, Stein Aerts, Fisun Hamaratoglu
Publikováno v:
Current Biology
Cancer cells have abnormal gene expression profiles; however, to what degree these are chaotic or driven by structured gene regulatory networks is often not known. Here we studied a model of Ras-driven invasive tumorigenesis in Drosophila epithelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c1c598a7036031a17e5ca88cc3305e
Autor:
Malini Natarajan, Fisun Hamaratoglu, Leticia Sansores-Garcia, Julia Zeitlinger, Georg Halder, Justine Pascual, Stein Aerts, Jelle Jacobs
Publikováno v:
Developmental cell. 42(6)
Hyperactivating mutations in Ras signaling are hallmarks of carcinomas. Ras signaling mediates cell fate decisions as well as proliferation during development. It is not known what dictates whether Ras signaling drives differentiation versus prolifer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa085b72014bb0cdaa2917cf5a9016a
https://pubmed.ncbi.nlm.nih.gov/28950097
https://pubmed.ncbi.nlm.nih.gov/28950097