Zobrazeno 1 - 10
of 883
pro vyhledávání: '"Fis1"'
Autor:
Xiaodong Li, Jingjing Tie, Yuze Sun, Chengrong Gong, Shizhou Deng, Xiyu Chen, Shujiao Li, Yaoliang Wang, Zhenhua Wang, Feifei Wu, Hui Liu, Yousheng Wu, Guopeng Zhang, Qingdong Guo, Yanling Yang, Yayun Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-34 (2024)
Abstract Background The dynamics of mitochondrial respiratory cristae (MRC) and its impact on oxidative phosphorylation (OXPHOS) play a crucial role in driving the progression of high-grade glioma (HGG). However, the underlying mechanism remains uncl
Externí odkaz:
https://doaj.org/article/56bb953149df4c158b95e18a344471d9
Autor:
Preethy S. Sridharan, Yeojung Koh, Emiko Miller, Di Hu, Suwarna Chakraborty, Sunil Jamuna Tripathi, Teresa R. Kee, Kalyani Chaubey, Edwin Vázquez-Rosa, Sarah Barker, Hui Liu, Rose A. León-Alvarado, Kathryn Franke, Coral J. Cintrón-Pérez, Matasha Dhar, Min-Kyoo Shin, Margaret E. Flanagan, Rudolph J. Castellani, Tamar Gefen, Marina Bykova, Lijun Dou, Feixiong Cheng, Brigid M. Wilson, Hisashi Fujioka, David E. Kang, Jung-A.A. Woo, Bindu D. Paul, Xin Qi, Andrew A. Pieper
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101715- (2024)
Summary: Progression of acute traumatic brain injury (TBI) into chronic neurodegeneration is a major health problem with no protective treatments. Here, we report that acutely elevated mitochondrial fission after TBI in mice triggers chronic neurodeg
Externí odkaz:
https://doaj.org/article/78517b6c384645a8be41713376606e5d
Autor:
Zhixia Song, Yao Xia, Lang Shi, Hongchu Zha, Jing Huang, Xiaohong Xiang, Huiming Li, Hua Huang, Ruchi Yue, Hongtao Wang, Jiefu Zhu
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-23 (2024)
Abstract Background Acute kidney injury (AKI) is a common clinical disorder with complex etiology and poor prognosis, and currently lacks specific and effective treatment options. Mitochondrial dynamics dysfunction is a prominent feature in AKI, and
Externí odkaz:
https://doaj.org/article/ffc7cd57f8f943378dbd5017610ac902
Glycyrrhizic acid rebalances mitochondrial dynamics to mitigate hepatotoxicity induced by triptolide
Autor:
Zhiwen Cao, Bin Liu, Lan Yan, Haiyang Shu, Lili Wang, Li Li, Peipei Lu, Xiaojuan He, Guilin Ouyang, Zhixin Nie, Aiping Lu, Cheng Lu
Publikováno v:
Journal of Functional Foods, Vol 113, Iss , Pp 106006- (2024)
Triptolide (TP) has various pharmacological activities, but its hepatotoxicity limits its therapeutic potential. Licorice has been evaluated to harmonize various medicines, and its active ingredient glycyrrhizic acid (GA) has been identified for its
Externí odkaz:
https://doaj.org/article/62a2785c0e164c6282a8f3a8fa39f674
Autor:
Mulate Zerihun, Nir Qvit
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Cardiovascular diseases (CVDs) are the most common non-communicable diseases globally. An estimated 17.9 million people died from CVDs in 2019, representing 32% of all global deaths. Mitochondria play critical roles in cellular metabolic homeostasis,
Externí odkaz:
https://doaj.org/article/727bed6556374036a8a26bccc5c51a93
Autor:
Yu-Mi Lee, Dong-Hee Choi, Jeong-Hye Park, Min-Woo Cheon, Jae Gwan Kim, Jeong-Sang Kim, Taejin Choi, Hye-Ran Kim, Daehwan Youn
Publikováno v:
Journal of Acupuncture & Meridian Studies, Vol 16, Iss 2, Pp 49-55 (2023)
Background : A significant amount of research has been conducted to establish the validity of acupuncture, and it has been demonstrated through animal disease model studies that acupuncture influences mitochondrial changes. However, to more accuratel
Externí odkaz:
https://doaj.org/article/4f23156369394f50b05af216c1ef8fd2
Akademický článek
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Akademický článek
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Publikováno v:
Fiyz̤, Vol 26, Iss 1, Pp 22-29 (2022)
Background: Aging can increase the risks of various liver diseases and act as an unfavorable prognostic factor and increase mortality. Therefore, this study aimed to investigate the effect of 8-week resistance training with liposomal vitamin C on t
Externí odkaz:
https://doaj.org/article/4d0aa086d2324ff7969bd460cee6c38a
Autor:
Doudou Liu, Zhiwei Sun, Ting Ye, Jingyuan Li, Bin Zeng, Qiting Zhao, Jianyu Wang, Hongmei Rosie Xing
Publikováno v:
FEBS Open Bio, Vol 11, Iss 7, Pp 1997-2007 (2021)
Mitophagy, a form of autophagy, plays a role in cancer development, progression and recurrence. Cancer stem cells (CSCs) also play a key role in these processes, although it not known whether mitophagy can regulate the stemness of CSCs. Here, we empl
Externí odkaz:
https://doaj.org/article/38eb882312fd43f69561a624d4b951cd