Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Firth Jc"'
Autor:
Karen H. Wolmarans, Firth Jc, Eric de Groot, Melchior C. Nierman, Anouk van der Graaf, A. David Marais
Publikováno v:
Acta paediatrica (Oslo, Norway, 95(11), 1461-1466. Wiley-Blackwell
AIM: To assess whether early initiation of statin therapy for heterozygous familial hypercholesterolaemia favourably affects lipid profiles or vascular morphological changes. METHODS: Children and adolescents aged 10-16 y with heterozygous familial h
Publikováno v:
Nephrology Dialysis Transplantation. 19:3176-3179
Publikováno v:
Seminars in Vascular Medicine. 4:43-50
Mutations in the low-density lipoprotein (LDL) receptor gene cause familial hypercholesterolemia. In homozygous familial hypercholesterolemia, both genes for the LDL- receptor are mutated and LDL levels are markedly elevated. High-density lipoprotein
Autor:
Therese Heinonen, D. Roger Illingworth, Anuradha S. Pappu, Gillian J. Pilcher, A. David Marais, Donald M. Black, Maritha J. Kotze, Firth Jc, Frederick J. Raal
Publikováno v:
Atherosclerosis. 150:421-428
Patients with homozygous familial hypercholesterolaemia (HoFH) have markedly elevated low density lipoprotein (LDL) cholesterol levels that are refractory to standard doses of lipid-lowering drug therapy. In the present study we evaluated the effect
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 10, Pp 2071-2078 (1997)
The Journal of Lipid Research
2071-208
The Journal of Lipid Research
2071-208
Apheresis only partially controls raised low density lipoprotein cholesterol levels in patients with homozygous fa- milial hypercholesterolemia, who usually respond poorly to lipid-lowering drugs. The efficacy and mechanism of action of a new 3-hydro
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 17:1527-1531
Abstract Hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors are the drugs of choice in heterozygous familial hypercholesterolemia (FH), which has a high risk of ischemic heart disease. An open-label study was conducted to test the effica
Publikováno v:
Seminars in Vascular Medicine. 4:93-95
South Africa, especially the Caucasian part of the population, has one of the highest incidences of familial hypercholesterolemia in the world. The founder effect in this region has led to this high incidence and to a limited number of mutations in t
Publikováno v:
Current atherosclerosis reports. 4(1)
Homozygous familial hypercholesterolemia is a rare disorder resulting in severe premature atherosclerosis. Drug therapy was previously viewed as inadequate for control of the dyslipidemia, so portacaval shunting, plasmapheresis, and liver transplanta
Autor:
Nigel B. Rendell, Graham W. Taylor, Gilbert R. Thompson, J. Mountney, Rossitza P. Naoumova, Firth Jc, A.D. Marais
Publikováno v:
Atherosclerosis. 119(2)
Fasting plasma mevalonic acid (MVA), an indicator of in vivo cholesterol synthesis, was measured in 35 patients with familial hypercholesterolaemia (FH) of whom 7 were treated with pravastatin 10-40 mg/day, 7 with simvastatin 10-40 mg/day and 21 with
Publikováno v:
Drugs Affecting Lipid Metabolism ISBN: 9789401066259
Drugs Affecting Lipid Metabolism
Drugs Affecting Lipid Metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::414368b8abbbbb44787da7a159af044d
https://doi.org/10.1007/978-94-009-0311-1_22
https://doi.org/10.1007/978-94-009-0311-1_22