Výsledky vyhledávání - "Firth, Martin"

Abstract Background Rearrangement of the mixed-lineage leukemia gene (MLL) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and resistance to glucocorticoids (GCs). We have recently observed that GC r

Externí odkaz: https://doaj.org/article/acef9bbe9153460680225ff2fa3628a7

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Akademický článek

Gene-based outcome prediction in multiple cohorts of pediatric T-cell acute lymphoblastic leukemia: a Children's Oncology Group study

Autor: Sturges Nina C, Firth Martin J, Beesley Alex H, Cleaver Amanda L, O'Leary Rebecca A, Hunger Stephen P, Baker David L, Kees Ursula R

Publikováno v: Molecular Cancer, Vol 9, Iss 1, p 105 (2010)

Abstract Background Continuous complete clinical remission in T-cell acute lymphoblastic leukemia (T-ALL) is now approaching 80% due to the implementation of aggressive chemotherapy protocols but patients that relapse continue to have a poor prognosi

Externí odkaz: https://doaj.org/article/f34b2a6dc7ee41059e441dda2ad1e8d0

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Akademický článek

Translating microarray data for diagnostic testing in childhood leukaemia

Autor: de Klerk Nicholas H, Beesley Alex H, Firth Martin J, Hoffmann Katrin, Kees Ursula R

Publikováno v: BMC Cancer, Vol 6, Iss 1, p 229 (2006)

Abstract Background Recent findings from microarray studies have raised the prospect of a standardized diagnostic gene expression platform to enhance accurate diagnosis and risk stratification in paediatric acute lymphoblastic leukaemia (ALL). Howeve

Externí odkaz: https://doaj.org/article/fc7bbfff4f4f4ea19799bbc3fffcca7f

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Akademický článek

Gene expression levels assessed by oligonucleotide microarray analysis and quantitative real-time RT-PCR – how well do they correlate?

Autor: Boag Joanne M, Freitas Joseph R, Terry Philippa A, Hoffmann Katrin, Beesley Alex H, Firth Martin J, Gottardo Nicholas G, Dallas Peter B, Cummings Aaron J, Kees Ursula R

Publikováno v: BMC Genomics, Vol 6, Iss 1, p 59 (2005)

Abstract Background The use of microarray technology to assess gene expression levels is now widespread in biology. The validation of microarray results using independent mRNA quantitation techniques remains a desirable element of any microarray expe

Externí odkaz: https://doaj.org/article/f2c17fcf274f49fa870d75ca2d701767

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