Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Firoj Mahmud"'
Autor:
Martin Smelik, Yelin Zhao, Xinxiu Li, Joseph Loscalzo, Oleg Sysoev, Firoj Mahmud, Dina Mansour Aly, Mikael Benson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Multiomics analyses have identified multiple potential biomarkers of the incidence and prevalence of complex diseases. However, it is not known which type of biomarker is optimal for clinical purposes. Here, we make a systematic comparison o
Externí odkaz:
https://doaj.org/article/0610a041cbff4011a859dc21633a9d55
Autor:
Kemal Avican, Jehad Aldahdooh, Matteo Togninalli, A. K. M. Firoj Mahmud, Jing Tang, Karsten M. Borgwardt, Mikael Rhen, Maria Fällman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Bacterial stress responses are potential targets for new antimicrobials. Here, Avican et al. present global transcriptomes for 32 bacterial pathogens grown under 11 stress conditions, and identify common and unique regulatory responses, as well as pr
Externí odkaz:
https://doaj.org/article/528c32ad693d42ecb0d3a057d1175df3
Autor:
Julius Semenas, Tianyan Wang, Azharuddin Sajid Syed Khaja, AKM Firoj Mahmud, Athanasios Simoulis, Thomas Grundström, Maria Fällman, Jenny L. Persson
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 968-986 (2021)
Selective ERα modulator, tamoxifen, is well tolerated in a heavily pretreated castration‐resistant prostate cancer (PCa) patient cohort. However, its targeted gene network and whether expression of intratumor ERα due to androgen deprivation thera
Externí odkaz:
https://doaj.org/article/76e6e359dd224187a7177058d52aa91f
Autor:
Abebe Aseffa Negeri, Hassen Mamo, Jyoti M. Gurung, A. K. M. Firoj Mahmud, Maria Fällman, Eyasu Tigabu Seyoum, Adey Feleke Desta, Matthew S. Francis
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The treatment of invasive Escherichia coli infections is a challenge because of the emergence and rapid spread of multidrug resistant strains. Particular problems are those strains that produce extended spectrum β-lactamases (ESBL’s). Although the
Externí odkaz:
https://doaj.org/article/4dea0eaa016f417e86ae344dd3af0581
Autor:
A. K. M. Firoj Mahmud, Kristina Nilsson, Anna Fahlgren, Roberto Navais, Rajdeep Choudhury, Kemal Avican, Maria Fällman
Publikováno v:
mSystems, Vol 5, Iss 6 (2020)
ABSTRACT RpoN, an alternative sigma factor commonly known as σ54, is implicated in persistent stages of Yersinia pseudotuberculosis infections in which genes associated with this regulator are upregulated. We here combined phenotypic and genomic ass
Externí odkaz:
https://doaj.org/article/a3a6c3d7038f4728b7349f8495a1f005
Publikováno v:
Journal of Computational Biology. 27:1313-1328
Multiple transcription factors (TFs) bind to specific sites in the genome and interact among themselves to form the cis-regulatory modules (CRMs). They are essential in modulating the expression of...
Autor:
A. K. M. Firoj Mahmud, Jehad Aldahdooh, Jing Tang, Mikael Rhen, Karsten M. Borgwardt, Kemal Avican, Maria Fällman, Matteo Togninalli
Publikováno v:
Nature Communications, 12 (1)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Bacterial processes necessary for adaption to stressful host environments are potential targets for new antimicrobials. Here, we report large-scale transcriptomic analyses of 32 human bacterial pathogens grown under 11 stress conditions mimicking hum
Autor:
Thomas Grundström, Tianyan Wang, Julius Semenas, Athanasios Simoulis, Akm Firoj Mahmud, Jenny L. Persson, Azharuddin Sajid Syed Khaja, Maria Fällman
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 15, Iss 4, Pp 968-986 (2021)
Molecular Oncology, Vol 15, Iss 4, Pp 968-986 (2021)
In the present study, we unrevealed the effect of tamoxifen on ERα and PIP5K1α/AKT that are responsible for prostate cancer growth and invasion. Tamoxifen in combination treatment with PIP5K1α inhibitor, ISA‐2011B, led to tumor regression in xen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a769dc8f7f3ab52e117a96615dd9746e
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-177666
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-177666
Autor:
Maria Fällman, Rajdeep Choudhury, Kemal Avican, Anna Fahlgren, Kristina Nilsson, A. K. M. Firoj Mahmud, Roberto Navais
Publikováno v:
mSystems, Vol 5, Iss 6 (2020)
mSystems
mSystems
The alternative sigma factor RpoN (σ54), which is widely distributed in eubacteria, has been implicated in controlling gene expression of importance for numerous functions including virulence. Proper responses to host environments are crucial for ba
SummarySince its introduction, RNA-seq technology has been used extensively in studies of pathogenic bacteria to identify and quantify differences in gene expression across multiple samples from bacteria exposed to different conditions. With some exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16029483e51858f1e0b2baa101ba7888
https://doi.org/10.1101/2020.06.09.135822
https://doi.org/10.1101/2020.06.09.135822