Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Firat Kaya"'
Autor:
Yitian Xu, Lihua Wang, Matthew D Zimmerman, Kai-Yuan Chen, Lu Huang, Dah-Jiun Fu, Firat Kaya, Nikolai Rakhilin, Evgeniya V Nazarova, Pengcheng Bu, Veronique Dartois, David G Russell, Xiling Shen
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006974 (2018)
Mycobacterium tuberculosis (Mtb) remains a grave threat to world health with emerging drug resistant strains. One prominent feature of Mtb infection is the extensive reprogramming of host tissue at the site of infection. Here we report that inhibitio
Externí odkaz:
https://doaj.org/article/27f94f175af94503a0107147390202b8
Akademický článek
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Autor:
Holly-May Lewis, Catia Costa, Véronique Dartois, Firat Kaya, Mark Chambers, Janella de Jesus, Vladimir Palitsin, Roger Webb, Melanie J. Bailey
Publikováno v:
Analytical Chemistry. 94:11798-11806
Elemental imaging is widely used for imaging cells and tissues but rarely in combination with organic mass spectrometry, which can be used to profile lipids and measure drug concentrations. Here, we demonstrate how elemental imaging and a new method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f3f8c5375052c979caff65193a731e
https://doi.org/10.1021/acs.analchem.2c01940
https://doi.org/10.1021/acs.analchem.2c01940
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Autor:
Nicholas D. Walter, Jackie P. Ernest, Christian Dide-Agossou, Allison A. Bauman, Michelle E. Ramey, Karen Rossmassler, Lisa M. Massoudi, Samantha Pauly, Reem Al Mubarak, Martin I. Voskuil, Firat Kaya, Jansy P. Sarathy, Matthew D. Zimmerman, Véronique Dartois, Brendan K. Podell, Radojka M. Savic, Gregory T. Robertson
Tuberculosis lung lesions are complex and harbor heterogeneous microenvironments that influence antibiotic effectiveness. Major strides have been made recently in understanding drug pharmacokinetics in pulmonary lesions, but the bacterial phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32c2774e6ba237d4dcbaa51a1145d6af
https://doi.org/10.1101/2023.02.03.527062
https://doi.org/10.1101/2023.02.03.527062
Autor:
Claire L Carter, Han Wang, Matthew C. Zimmerman, Jansy Sarathy, Véronique Dartois, Ning Wang, Firat Kaya
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32:2664-2674
Mass spectrometry imaging investigations of tissues infected with agents that require high-security biocontainment, such as Mycobacterium tuberculosis, have been limited due to incompatible sterilization techniques. Here we describe an on-slide heat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf090c1db784fbbb51e467774a9e20b2
https://doi.org/10.1021/jasms.1c00205
https://doi.org/10.1021/jasms.1c00205
Autor:
Firat Kaya, Matthew D. Zimmerman, Rosleine Antilus-Sainte, Martin Gengenbacher, Claire L. Carter, Véronique Dartois
Publikováno v:
Analytical and bioanalytical chemistry. 414(23)
Bones are the site of multiple diseases requiring chemotherapy, including cancer, arthritis, osteoporosis and infections. Yet limited methodologies are available to investigate the spatial distribution and quantitation of small molecule drugs in bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d881aa4f29ee5d37c290843739048c
https://pubmed.ncbi.nlm.nih.gov/35945288
https://pubmed.ncbi.nlm.nih.gov/35945288
Autor:
Firat Kaya, Jacqueline P. Ernest, Katherine LoMauro, Martin Gengenbacher, Abdeldjalil Madani, Wassihun Wedajo Aragaw, Matthew D. Zimmerman, Jansy P. Sarathy, Nadine Alvarez, Isaac Daudelin, Han Wang, Faye Lanni, Danielle M. Weiner, Laura E. Via, Clifton E. Barry, Kenneth N. Olivier, Thomas Dick, Brendan K. Podell, Radojka M. Savic, Véronique Dartois
Publikováno v:
Antimicrob Agents Chemother
Antimicrobial agents and chemotherapy, vol 66, iss 3
Antimicrobial agents and chemotherapy, vol 66, iss 3
Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a potentially fatal infectious disease requiring long treatment duration with multiple antibiotics and against which there is no reliable cure. Among the factors that have hampered the develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73437e3bfdd6dc8ae59d4155e1b4de2e
https://doi.org/10.1128/aac.02212-21
https://doi.org/10.1128/aac.02212-21
Autor:
Ning, Wang, Jansy P, Sarathy, Matthew, Zimmerman, Firat, Kaya, Han, Wang, Véronique, Dartois, Claire L, Carter
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32(11)
Mass spectrometry imaging investigations of tissues infected with agents that require high-security biocontainment, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff451586ab18b27ae2a4a3caad317e66
https://pubmed.ncbi.nlm.nih.gov/34672552
https://pubmed.ncbi.nlm.nih.gov/34672552
Autor:
Mike A. Lyons, Barbara Graham, Ekaterina Maidj, Anne J. Lenaerts, Dashick W. L. Scott, Franceen Eshun-Wilson, Matt Zimmerman, Gregory T. Robertson, Michelle E. Ramey, Brendan K. Podell, Véronique Dartois, Firat Kaya, Bryce C. Asay, Courtney Hastings, Lisa M. Massoudi, Joshua Vasquez, Lisa K. Woolhiser, Veronica Gruppo, Claire L. Carter
Publikováno v:
Antimicrobial Agents and Chemotherapy
Multiple drug discovery initiatives for tuberculosis are currently ongoing to identify and develop new potent drugs with novel targets in order to shorten treatment duration. One of the drug classes with a new mode of action is DprE1 inhibitors targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e510dfb090f045f63f9ccd0aa795aebb
https://doi.org/10.1128/aac.00583-21
https://doi.org/10.1128/aac.00583-21